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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sagebrecht, Jurgen | SP | Vermont Lake Monsters | 24 | 08/03/2002 | New Milford | USA | Right | Right | 6' 7" | 235 lbs | - |
| Salinas, Juan | 3B | Alloway Halberds | 25 | 02/26/2001 | Santo Domingo | DOM | Right | Right | 6' 1" | 190 lbs | $280,000 |
| Sam, Janghyun | 2B | Vermont Lake Monsters | 25 | 12/31/2001 | Suncheon | KOR | Switch | Right | 6' 1" | 190 lbs | $280,000 |
| Samurakami, Yoshihito | C | Houston BC | 24 | 05/16/2002 | Takasago | JPN | Right | Right | 6' 5" | 240 lbs | - |
| Sánchez, António | CF | Free Agent | 27 | 02/17/1999 | Ramón Santana | DOM | Right | Right | 6' 4" | 210 lbs | - |
| Sánchez, Juan | RP | Jersey City Sun Caps | 25 | 09/09/2001 | Cumana | VEN | Right | Right | 5' 11" | 185 lbs | $280,000 |
| Sanders, Israel | SS | Florida Men | 27 | 08/27/1999 | Dallas | USA | Right | Right | 6' 4" | 225 lbs | $280,000 |
| Sanderson, Kevin | LF | Free Agent | 30 | 05/22/1996 | Beacon Square | USA | Right | Right | 6' 0" | 210 lbs | - |
| Sato, Reijiro | C | Free Agent | 34 | 06/15/1992 | Yamatotakada | JPN | Left | Right | 5' 11" | 220 lbs | - |
| Scalabrine, Brian | SP | Florida Men | 25 | 06/21/2001 | Berkeley Lake | USA | Right | Right | 5' 11" | 190 lbs | - |
| Schneider, Bill | RP | Free Agent | 35 | 07/10/1991 | Arlington | USA | Switch | Right | 5' 11" | 200 lbs | - |
| Silva, Jorge | SP | Florida Men | 29 | 03/25/1997 | Valencia | VEN | Right | Right | 6' 2" | 210 lbs | - |
| Silva, Pedro | RP | Jersey City Sun Caps | 24 | 07/12/2002 | Tulsa | USA | Right | Right | 6' 1" | 195 lbs | - |
| Smeddon, Alexis | 3B | Tortolita Drummers | 29 | 12/20/1997 | Stockton | USA | Right | Right | 5' 11" | 200 lbs | - |
| Smerdon, Dave | CF | Pennsauken Flyers | 23 | 10/16/2003 | Redmond | USA | Left | Left | 6' 0" | 190 lbs | - |
| Smith, Adrian | 1B | Vermont Lake Monsters | 28 | 03/21/1998 | Alexandria | USA | Right | Right | 5' 11" | 225 lbs | $1,200,000 |
| Smith, Noah | 2B | Alloway Halberds | 26 | 09/12/2000 | Bedford | USA | Right | Right | 5' 11" | 185 lbs | - |
| Sommer, Chris | SP | Jersey City Sun Caps | 24 | 11/04/2002 | Yeehaw Junction | USA | Left | Left | 6' 2" | 220 lbs | - |
| Sosa, Tom | RP | Augusta Timber Hawks | 31 | 03/18/1995 | Normal | USA | Right | Right | 6' 5" | 225 lbs | - |
| Stewart, Lindsay | CF | Jersey City Sun Caps | 32 | 06/12/1994 | Jacksonville | USA | Right | Right | 5' 11" | 195 lbs | - |
| Stockman, Dave | LF | Pennsauken Flyers | 27 | 09/26/1999 | Savannah | USA | Right | Right | 5' 11" | 225 lbs | - |
| Strauss, Billy | CF | Phoenix Hotspur Reserves | 29 | 10/02/1997 | Gary | USA | Right | Right | 6' 3" | 215 lbs | - |
| Suárez, Galtero | C | Augusta Timber Hawks | 20 | 04/02/2006 | Santo Domingo | DOM | Switch | Right | 6' 0" | 185 lbs | - |
| Sun, Decheng | CL | Houston BC | 32 | 09/25/1994 | Taichung | TPE | Right | Right | 6' 1" | 215 lbs | $4,600,000 |
| Sweeny, Blair | C | Tortolita Drummers | 24 | 07/29/2002 | Taree | AUS | Right | Right | 6' 1" | 200 lbs | - |
