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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saikawa, Tomiji | RP | Mercer Island Screaming Eagles | 31 | 11/11/1994 | Tokyo | JPN | Right | Left | 6' 0" | 195 lbs | - |
| Salazar, Ángel | SP | Lannister United Lionhearts | 22 | 02/20/2003 | Sagua la Grande | CUB | Right | Right | 6' 3" | 210 lbs | - |
| Saldaña, Jorge | SS | Casper Ghosts | 25 | 06/03/2000 | Monte Plata | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Sánchez, Gonzalo | 3B | Minnesota Loons | 23 | 04/25/2002 | Pinar del Rio | CUB | Right | Right | 6' 0" | 190 lbs | - |
| Sánchez, José | C | Sun Prairie Swallows | 26 | 11/19/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 225 lbs | - |
| Sanders, Bryan | SS | Chesapeake Continentals | 25 | 09/19/2000 | Ft. Wayne | USA | Right | Right | 5' 11" | 190 lbs | - |
| Sandoval, Ken | 2B | Chesapeake Continentals | 22 | 03/23/2003 | Columbus | USA | Right | Right | 6' 1" | 190 lbs | - |
| Santos, Francisco | 2B | Minnesota Loons | 23 | 06/03/2002 | Guadalupe | COL | Left | Right | 6' 1" | 185 lbs | - |
| Scalabrine, Brian | SP | Casper Ghosts | 24 | 06/21/2001 | Berkeley Lake | USA | Right | Right | 5' 11" | 185 lbs | - |
| Schroeder, Dave | 3B | Free Agent | 25 | 08/30/2000 | Roanoke | USA | Right | Right | 6' 1" | 210 lbs | - |
| Scott, Edward | RP | Tacoma Fur Traders | 28 | 01/16/1997 | River Edge | USA | Right | Right | 6' 3" | 220 lbs | - |
| Seacat, IV | SS | Lannister United Lionhearts | 22 | 12/19/2003 | Southlake | USA | Right | Right | 6' 1" | 185 lbs | - |
| Shafer, Chad | C | Yakima Hops | 23 | 04/13/2002 | San Antonio | USA | Right | Right | 6' 3" | 210 lbs | - |
| Shaikh, Hubert | SP | Athletic Club KC Academy | 21 | 01/23/2004 | South Lake Tahoe | USA | Right | Right | 5' 8" | 165 lbs | - |
| Shelton, Ken | RP | Mercer Island Screaming Eagles | 25 | 07/28/2000 | Norfolk | USA | Right | Right | 6' 8" | 235 lbs | - |
| Sherman, Thomas | LF | Chesapeake Continentals | 25 | 02/02/2000 | Candia | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Silva, José | CF | Sun Prairie Swallows | 24 | 02/26/2001 | El Seibo | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Silva, Pedro | SP | Chesapeake Continentals | 23 | 07/12/2002 | Tulsa | USA | Right | Right | 6' 1" | 195 lbs | - |
| Silva, Roberto | SP | Yakima Hops | 23 | 02/16/2002 | Acarigua | VEN | Left | Left | 6' 6" | 215 lbs | - |
| Simmons, Earl | SP | Casper Ghosts | 24 | 02/12/2001 | Mt. Vernon | USA | Right | Right | 6' 0" | 190 lbs | - |
| Simpson, John | RP | Free Agent | 26 | 12/25/1999 | Woodburn | USA | Right | Right | 6' 5" | 215 lbs | - |
| Singer, Eddie | RP | Free Agent | 26 | 03/21/1999 | Essex Fells | USA | Right | Right | 5' 9" | 185 lbs | - |
| Sirica, John | RP | Yakima Hops | 24 | 07/04/2001 | Los Angeles | USA | Left | Right | 6' 2" | 200 lbs | - |
| Skelly, Bryant | CF | Yakima Hops | 21 | 04/29/2004 | Oklahoma City | USA | Right | Right | 6' 2" | 195 lbs | - |
| Snyder, Anthony | RP | Casper Ghosts | 32 | 04/20/1993 | Brooklyn | USA | Right | Right | 6' 0" | 200 lbs | - |
| Soto, Júlio | SS | Minnesota Loons | 23 | 01/06/2002 | Neyba | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Stephens, Ted | 2B | Athletic Club KC Academy | 24 | 03/19/2001 | Augusta | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stockman, Dave | LF | Minnesota Loons | 26 | 09/26/1999 | Savannah | USA | Right | Right | 5' 11" | 215 lbs | - |
| Suárez, Juan | C | Chesapeake Continentals | 24 | 12/22/2001 | Doxey | MEX | Right | Right | 6' 3" | 225 lbs | - |
| Sutherland, Jack | 2B | Asheville Highlanders | 23 | 07/24/2002 | Winton | USA | Left | Right | 6' 3" | 205 lbs | - |
| Swanson, Martin | RP | Chesapeake Continentals | 24 | 01/22/2001 | Watertown | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sweeny, Nigel | RP | Yakima Hops | 24 | 11/04/2001 | Shoalhaven | AUS | Right | Right | 6' 4" | 205 lbs | - |
