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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabastro, Lorenzo | SS | Pure Michigan Great Lakers | 23 | 01/13/2000 | Fusagasuga | COL | Right | Right | 6' 1" | 195 lbs | $280,000 |
| Saginov, Justin | C | Pawnee ParksNRec | 26 | 11/29/1997 | Portland | USA | Right | Right | 6' 4" | 225 lbs | $280,000 |
| Sakamoto, Toshitsugu | RF | Port Royal Disaster | 34 | 02/20/1989 | Kumamoto | JPN | Right | Right | 6' 4" | 230 lbs | - |
| Salazar, Jorge | C | Brinkley Belugas | 29 | 02/08/1994 | Artemisa | CUB | Right | Right | 6' 0" | 215 lbs | - |
| Salcido, Julián | CF | Pawnee ParksNRec | 19 | 03/19/2004 | La Romana | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sameiro, Arsenio | C | Port Royal Disaster | 22 | 07/18/2001 | Capitão Poço | BRA | Switch | Right | 5' 10" | 195 lbs | - |
| Sánchez, Pedro | 3B | Free Agent | 32 | 01/21/1991 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 225 lbs | - |
| Sanders, Nelson | 3B | Port Royal Disaster | 28 | 08/24/1995 | Healdsburg | USA | Left | Right | 6' 0" | 220 lbs | - |
| Sandoval, José | RP | Scranton Supernovas | 24 | 04/05/1999 | Santo Domingo | DOM | Left | Left | 6' 8" | 215 lbs | - |
| Sandoval, Juan | C | Wilmington Bay Hawks | 23 | 05/14/2000 | Azua | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Sasaki, Yoshiyuki | RF | Free Agent | 34 | 09/30/1989 | Taketa | JPN | Right | Right | 5' 10" | 220 lbs | - |
| Schaefer, Chris | RP | Wilmington Bay Hawks | 30 | 04/27/1993 | Dallas | USA | Right | Right | 6' 2" | 210 lbs | $1,500,000 |
| Schiffer, Lance | CF | Hamilton Coyotes | 26 | 03/20/1997 | Sterling | USA | Left | Left | 5' 11" | 185 lbs | - |
| Schmitt, Jack | RF | Gryfindor Braves | 26 | 11/12/1997 | Portland | USA | Left | Left | 6' 4" | 230 lbs | $280,000 |
| Schneider, Jeff | RP | Scranton Supernovas | 23 | 06/03/2000 | Cincinnati | USA | Right | Left | 6' 3" | 195 lbs | - |
| Seixal, Quintiliano | SP | Alaskan Humpbacks | 22 | 07/17/2001 | Teresópolis | BRA | Right | Right | 6' 4" | 200 lbs | - |
| Shankle, Jon | RP | Santa Barbara Golden Cranes | 30 | 07/20/1993 | Bonadelle Ranchos-Madera Ranchos | USA | Switch | Right | 6' 2" | 205 lbs | - |
| Shannon, Wes | CF | Port Royal Disaster | 22 | 07/03/2001 | Aurora | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sharp, Monty | RF | Hamilton Coyotes | 25 | 05/02/1998 | West Valley | USA | Right | Right | 6' 0" | 195 lbs | - |
| Shaw, Joe | SS | Free Agent | 34 | 10/26/1989 | North Babylon | USA | Right | Right | 6' 3" | 215 lbs | - |
| Shaw, Stu | 2B | Port Royal Disaster | 28 | 03/16/1995 | West Orange | USA | Right | Right | 6' 1" | 205 lbs | - |
| Shaw, Theodore | RF | Sioux Falls Red Pandas | 33 | 07/06/1990 | Charlotte | USA | Left | Left | 6' 1" | 215 lbs | - |
| Shirley, John | SP | Wilmington Bay Hawks | 24 | 07/22/1999 | Appleton | USA | Right | Right | 6' 5" | 205 lbs | - |
| Si, Jen-djieh | RP | Wilmington Bay Hawks | 25 | 06/20/1998 | Taipei | TPE | Right | Right | 6' 0" | 200 lbs | - |
| Silva, Manuel | RP | Free Agent | 26 | 12/15/1997 | Moca | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Michael | 1B | Gryfindor Braves | 28 | 06/22/1995 | Minneapolis | USA | Left | Left | 6' 5" | 255 lbs | $280,000 |
| Smith, Paul | 3B | Free Agent | 33 | 11/18/1990 | Waterbury | USA | Left | Right | 5' 11" | 225 lbs | - |
| Snel, Cor | RP | Scranton Supernovas | 22 | 10/15/2001 | Tera Kora | ANT | Right | Right | 6' 2" | 200 lbs | - |
| Sorensen, James | LF | Free Agent | 31 | 04/22/1992 | Staten Island | USA | Left | Left | 6' 0" | 200 lbs | - |
| Soto, Ismael | SP | Sioux Falls Red Pandas | 22 | 12/20/2001 | Sabana Grande de Palenque | DOM | Right | Right | 6' 8" | 225 lbs | - |
| Spencer, Cullen | 3B | Pure Michigan Great Lakers | 30 | 02/26/1993 | New Orleans | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stanford, Ethan | SS | Scranton Supernovas | 26 | 03/18/1997 | Battle Creek | USA | Right | Right | 6' 1" | 205 lbs | - |
| Stankovic, Branislav | RP | Free Agent | 29 | 03/11/1994 | Camp Pendleton South | USA | Right | Right | 6' 0" | 185 lbs | - |
| Stanley, Tommy | CF | Alaskan Humpbacks | 26 | 08/30/1997 | Stanton | USA | Right | Right | 5' 11" | 195 lbs | - |
| Stephenson, Gabe | RP | Gryfindor Braves | 23 | 03/04/2000 | Pleasant View | USA | Right | Right | 6' 3" | 200 lbs | - |
| Stewart, Bob | RP | Free Agent | 27 | 02/04/1996 | Port Orange | USA | Right | Left | 6' 4" | 205 lbs | - |
| Suárez, Alfredo | CF | Pawnee ParksNRec | 21 | 05/27/2002 | Managua | NCA | Right | Right | 6' 2" | 175 lbs | - |
