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| Saturday, December 31st, 2022 |
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| Alaskan Humpbacks: C Andrés Ibarra becomes a free-agent. |
| Scranton Supernovas: RP Ray Gordon becomes a free-agent. |
| Vermont Lake Monsters: RF Jason Powell becomes a free-agent. |
| Vermont Lake Monsters: SS Brent Barlow becomes a free-agent. |
| Vermont Lake Monsters: RP Fernando Ruíz becomes a free-agent. |
| Vermont Lake Monsters: SS Craig Stewart becomes a free-agent. |
| Vermont Lake Monsters: 2B Joe Shaw becomes a free-agent. |
| Pawnee ParksNRec: SS Lúcio Montoya becomes a free-agent. |
| Santa Barbara Golden Cranes: RP Ramiro Lara becomes a free-agent. |
| Santa Barbara Golden Cranes: SP Lance Hodges becomes a free-agent. |
| Wednesday, November 9th, 2022 |
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| Hamilton Coyotes: RP Clarence Ramsey becomes a free-agent. |
| Hamilton Coyotes: 2B Vicente Toro becomes a free-agent. |
| Hamilton Coyotes: 3B Raúl Valadez becomes a free-agent. |
| Sioux Falls Red Pandas: RP Paul O'Callahan becomes a free-agent. |
| Scranton Supernovas: RP Carlos Villarreal becomes a free-agent. |
| Pawnee ParksNRec: 1B Yoshiyuki Sasaki becomes a free-agent. |
| Monday, October 24th, 2022 |
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| Hamilton Coyotes: Signed pitching coach Scott Wilkerson. |
| Wednesday, October 19th, 2022 |
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| Vermont Lake Monsters: SP Ryan Ray retires. |
| Gryfindor Braves: Signed manager José Flores. |
| Sunday, October 16th, 2022 |
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| Scranton Supernovas: Signed hitting coach Adam Allen. |
| Saturday, October 15th, 2022 |
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| Hamilton Coyotes: Signed hitting coach Adrián Castillo. |
| Thursday, October 6th, 2022 |
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| Houston BC: Signed hitting coach Eric Martínez. |
| Wednesday, October 5th, 2022 |
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| Port Royal Disaster: Signed manager Davis Burt. |
| Sunday, October 2nd, 2022 |
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| Sioux Falls Red Pandas: Received RF Pancho Ruíz from Major League Level Montana. |
| Wednesday, September 28th, 2022 |
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| Sunset District Fog: Signed Manager Paul McMahon to a 3-year contract extension. |
| Sunset District Fog: Signed Hitting Coach Jorge González to a 2-year contract extension. |
| Sunset District Fog: Received SP Arnaldo Bodabalho from Major League Level Oakland. |
| Sunset District Fog: Promoted RP José Caballero to Major League Level Oakland. |
| Sunday, September 25th, 2022 |
|---|
| Port Royal Disaster: 1B Guillermo Romero retires. |
| Santa Barbara Golden Cranes: RP Ramón Aguilera retires. |
| Vermont Lake Monsters: LF Taroemon Watanabe retires. |
| Port Royal Disaster: MA Manolo Gallardo retires. |
| Hamilton Coyotes: Pitching Coach Ralph Harlan leaves the team, his contract was not renewed. |
| Hamilton Coyotes: Hitting Coach Belarmino Boubret leaves the team, his contract was not renewed. |
| Alaskan Humpbacks: Manager Willis Crawford leaves the team, his contract was not renewed. |
| Alaskan Humpbacks: Hitting Coach Nick Parker leaves the team, his contract was not renewed. |
| Scranton Supernovas: Pitching Coach José Muñóz leaves the team, his contract was not renewed. |
| Scranton Supernovas: Hitting Coach Manny Rodríguez leaves the team, his contract was not renewed. |
| Houston BC: Pitching Coach Soong-yong Kim leaves the team, his contract was not renewed. |
| Port Royal Disaster: Signed Hitting Coach Elliott Taylor to a 2-year contract extension. |
