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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Luis | 1B | Hialeah Dodos | 26 | 02/26/1994 | Tulsa | USA | Right | Right | 6' 0" | 220 lbs | - |
| Salazar, José | RF | Augusta Timber Hawks | 25 | 09/16/1995 | Tampa | USA | Switch | Left | 6' 3" | 230 lbs | - |
| Sánchez, Carlos | SP | Scranton Supernovas | 19 | 06/04/2001 | Maracaibo | VEN | Left | Left | 6' 2" | 180 lbs | - |
| Sánchez, Eduardo | SS | Sioux Falls Red Pandas | 21 | 11/01/1999 | Jeffersonville | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sánchez, Shawn | SS | Wilmington Bay Hawks | 21 | 03/29/1999 | North Richland Hills | USA | Switch | Right | 6' 0" | 180 lbs | $280,000 |
| Santana, António | C | Free Agent | 31 | 02/07/1989 | Rexburg | USA | Right | Right | 6' 0" | 215 lbs | - |
| Santos, Carlos | SS | Vermont Lake Monsters | 22 | 01/10/1998 | Los Angeles | USA | Right | Right | 6' 2" | 190 lbs | - |
| Santos, Javier | SS | Hialeah Dodos | 20 | 08/30/2000 | Turmero | VEN | Right | Right | 6' 1" | 170 lbs | - |
| Santos, Nathan | CF | Wilmington Bay Hawks | 32 | 08/12/1988 | Manhattan | USA | Left | Left | 6' 1" | 200 lbs | $7,500,000 |
| Sato, Reijiro | C | Vermont Lake Monsters | 28 | 06/15/1992 | Yamatotakada | JPN | Left | Right | 5' 11" | 210 lbs | $280,000 |
| Sawallisch, Han | RP | Brinkley Belugas | 31 | 11/02/1989 | Zweibrücken | GER | Left | Left | 6' 0" | 210 lbs | - |
| Schiffer, Lance | CF | Sioux Falls Red Pandas | 23 | 03/20/1997 | Sterling | USA | Left | Left | 5' 11" | 175 lbs | - |
| Schroeder, Derek | 2B | Balboa Buccaneers | 30 | 06/12/1990 | Dallas | USA | Right | Right | 5' 11" | 195 lbs | - |
| Scott, Freddy | 1B | Free Agent | 30 | 02/24/1990 | Queens | USA | Right | Right | 6' 0" | 230 lbs | - |
| Scott, Peter | RP | Vermont Lake Monsters | 33 | 09/27/1987 | New York | USA | Right | Right | 5' 10" | 200 lbs | - |
| Shaffer, Roger | LF | Brinkley Belugas | 34 | 01/03/1986 | St. Louis | USA | Left | Left | 6' 2" | 210 lbs | - |
| Sharp, Monty | CF | Lévis Rocks | 22 | 05/02/1998 | West Valley | USA | Right | Right | 6' 0" | 190 lbs | - |
| Shaw, Theodore | RF | Brinkley Belugas | 30 | 07/06/1990 | Charlotte | USA | Left | Left | 6' 1" | 215 lbs | $280,000 |
| Silva, Luis | C | Sunset District Fog | 25 | 01/25/1995 | San Diego | USA | Right | Right | 6' 2" | 240 lbs | - |
| Simpson, Harry | C | Free Agent | 31 | 04/06/1989 | New York | USA | Right | Right | 6' 1" | 240 lbs | - |
| Smith, Jared | RF | Alaskan Humpbacks | 32 | 11/30/1988 | Frostburg | USA | Right | Right | 6' 1" | 230 lbs | $280,000 |
| Smith, Walt | C | Balboa Buccaneers | 34 | 04/03/1986 | Visalia | USA | Switch | Right | 5' 11" | 215 lbs | - |
| Sorensen, James | LF | Alaskan Humpbacks | 28 | 04/22/1992 | Staten Island | USA | Left | Left | 6' 0" | 205 lbs | - |
| Sosa, Tom | RP | Augusta Timber Hawks | 25 | 03/18/1995 | Normal | USA | Right | Right | 6' 5" | 215 lbs | - |
| Stanford, Ethan | SS | Scranton Supernovas | 23 | 03/18/1997 | Battle Creek | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stankovic, Branislav | RP | Vermont Lake Monsters | 26 | 03/11/1994 | Camp Pendleton South | USA | Right | Right | 6' 0" | 180 lbs | - |
| Strickland, Tom | 3B | Augusta Timber Hawks | 23 | 01/25/1997 | Oberlin | USA | Right | Right | 5' 11" | 195 lbs | - |
| Sullivan, Don | RF | Free Agent | 28 | 09/20/1992 | South Beloit | USA | Left | Left | 6' 1" | 200 lbs | - |
| Sullivan, Woody | SP | Scranton Supernovas | 23 | 09/02/1997 | Plymouth Township | USA | Left | Left | 6' 1" | 200 lbs | - |
| Suto, Masaharu | RP | Free Agent | 36 | 02/11/1984 | Osaka | JPN | Right | Right | 6' 2" | 205 lbs | - |
