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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabastro, Lorenzo | CF | Mancelona Torch | 20 | 01/13/2000 | Fusagasuga | COL | Right | Right | 6' 1" | 180 lbs | - |
| Salinas, Juan | 3B | Syracuse Storm | 19 | 02/26/2001 | Santo Domingo | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sánchez, Alfredo | SP | Galesburg Guzzlers | 17 | 10/01/2003 | Juan de Acosta | COL | Left | Left | 6' 4" | 185 lbs | - |
| Sánchez, Manuel | SP | Galesburg Guzzlers | 18 | 08/22/2002 | San Juan de la Maguana | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Sandoval, Cristián | SP | Hammond Herons | 19 | 01/09/2001 | Alcalde Díaz | PAN | Right | Right | 6' 3" | 175 lbs | - |
| Santos, Albert | SS | Galesburg Guzzlers | 21 | 12/05/1999 | Filas de Mariche | VEN | Switch | Right | 6' 3" | 190 lbs | - |
| Santos, Pedro | 2B | Syracuse Storm | 21 | 07/27/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Scott, James | SP | South Beach Blaze | 21 | 03/06/1999 | Tacoma | USA | Left | Left | 6' 3" | 195 lbs | - |
| Shelton, Ken | RP | Nebraska Plainsmen | 20 | 07/28/2000 | Norfolk | USA | Right | Right | 6' 8" | 215 lbs | - |
| Sheppard, Ricky | SP | Galesburg Guzzlers | 21 | 04/01/1999 | Old Orchard Beach | USA | Left | Left | 6' 7" | 225 lbs | - |
| Silva, António | RP | Athletic Club KC U-21 | 21 | 01/20/1999 | Maturín | VEN | Left | Left | 6' 3" | 180 lbs | - |
| Silva, Marcos | C | Idaho Falls Chukars | 18 | 01/07/2002 | Baracoa | CUB | Right | Right | 6' 1" | 195 lbs | - |
| Silverstro, Jorge | SP | Gwinnett County Black Cats | 21 | 04/17/1999 | Sabanitas | PAN | Right | Right | 6' 2" | 190 lbs | - |
| Simpson, John | RP | Athletic Club KC U-21 | 21 | 12/25/1999 | Woodburn | USA | Right | Right | 6' 5" | 205 lbs | - |
| Smith, Noah | 2B | Syracuse Storm | 20 | 09/12/2000 | Bedford | USA | Right | Right | 5' 11" | 175 lbs | - |
| Soto, Brian | CF | Hammond Herons | 20 | 02/02/2000 | College Park | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sparks, Winston | 2B | South Beach Blaze | 20 | 12/26/2000 | Naperville | USA | Right | Right | 5' 10" | 175 lbs | - |
| Suárez, Jorge | 1B | Put-In-Bay BC | 20 | 04/25/2000 | Azua | DOM | Right | Right | 6' 5" | 220 lbs | - |
| Sutton, Joe | SS | South Beach Blaze | 21 | 09/25/1999 | Benicia | USA | Left | Right | 6' 2" | 190 lbs | - |
