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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Emílio | RF | Athletic Club KC | 27 | 11/24/1992 | Baltimore | USA | Left | Left | 5' 10" | 200 lbs | $10,100,000 |
| Sakai, Naohiro | SS | Athletic Club KC | 18 | 11/08/2001 | Matsumoto | JPN | Left | Right | 6' 1" | 165 lbs | - |
| Sakamoto, Toshitsugu | RF | Free Agent | 30 | 02/20/1989 | Kumamoto | JPN | Right | Right | 6' 4" | 235 lbs | - |
| Salazar, Héctor | SP | New Amsterdam Republics | 17 | 12/08/2002 | Guatire | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Sameiro, Arsenio | C | Rocky Mountain Nuggets | 18 | 07/18/2001 | Capitão Poço | BRA | Switch | Right | 5' 10" | 190 lbs | - |
| Sánchez, António | CF | Columbus Tidal Waves | 20 | 02/17/1999 | Ramón Santana | DOM | Right | Right | 6' 4" | 195 lbs | $280,000 |
| Sánchez, Carlos | SP | Philadephia 1776 BC | 17 | 05/03/2002 | El Pino | HON | Left | Right | 6' 2" | 175 lbs | - |
| Sánchez, Enrique | 1B | Chicago Gold Sox | 17 | 10/29/2002 | Charallave | VEN | Left | Left | 6' 6" | 200 lbs | - |
| Sánchez, Jorge | SP | Detroit Reapers | 18 | 04/05/2001 | Xico | MEX | Left | Left | 6' 0" | 165 lbs | - |
| Sánchez, Juan | SP | New Amsterdam Republics | 18 | 09/09/2001 | Cumana | VEN | Right | Right | 5' 11" | 170 lbs | - |
| Sánchez, Manuel | SP | Philadephia 1776 BC | 19 | 01/04/2000 | Catia La Mar | VEN | Left | Left | 6' 7" | 200 lbs | - |
| Sandoval, Cristián | SP | Chicago Gold Sox | 18 | 01/09/2001 | Alcalde Díaz | PAN | Right | Right | 6' 3" | 170 lbs | - |
| Santana, António | C | Wizarding AC Ravenclaws | 30 | 02/07/1989 | Rexburg | USA | Right | Right | 6' 0" | 210 lbs | $480,000 |
| Savage, Will | SP | Columbus Tidal Waves | 31 | 09/10/1988 | Florida Ridge | USA | Left | Left | 6' 0" | 210 lbs | $4,550,000 |
| Schenkel, Todd | SS | Columbus Tidal Waves | 33 | 02/23/1986 | Cairns | AUS | Switch | Right | 6' 0" | 200 lbs | $9,210,000 |
| Schneider, Bill | CL | Vancouver Grey Wolves | 28 | 07/10/1991 | Arlington | USA | Switch | Right | 5' 11" | 195 lbs | $2,030,000 |
| Schultz, Carlos | CF | Las Vegas Flamingos | 19 | 01/09/2000 | Melbourne | AUS | Switch | Left | 6' 1" | 180 lbs | - |
| Scott, Chip | MR | Athletic Club KC | 27 | 12/29/1992 | Indian Springs Village | USA | Right | Right | 6' 2" | 215 lbs | $441,000 |
| Scott, Tyrone | SS | Chicago Gold Sox | 26 | 07/09/1993 | Ft. Carson | USA | Right | Right | 6' 2" | 195 lbs | $8,715,000 |
| Serna, José | 2B | Richardson City Thundercats | 19 | 12/02/2000 | Santiago | DOM | Left | Right | 6' 1" | 185 lbs | - |
| Shaffer, Cole | 2B | Wizarding AC Ravenclaws | 22 | 07/14/1997 | New York | USA | Right | Right | 6' 0" | 180 lbs | $280,000 |
| Shearman, Henrique | C | Philadephia 1776 BC | 18 | 11/27/2001 | Valparaiso de Goias | BRA | Right | Right | 5' 11" | 180 lbs | - |
| Shelton, Ronald | 2B | New Amsterdam Republics | 29 | 05/20/1990 | Windham | USA | Right | Right | 5' 10" | 185 lbs | $4,200,000 |
| Sheppard, Matt | 3B | Las Vegas Flamingos | 23 | 11/14/1996 | Vermillion | USA | Right | Right | 5' 9" | 170 lbs | $1,000,000 |
| Sherratt, David | SP | Philadephia 1776 BC | 17 | 02/03/2002 | Reading | ENG | Left | Left | 6' 2" | 185 lbs | - |
| Silva, Edward | MR | Free Agent | 34 | 01/12/1985 | Nelsonville | USA | Right | Right | 5' 9" | 180 lbs | - |
| Silva, Héctor | SP | Richardson City Thundercats | 18 | 01/20/2001 | Charallave | VEN | Left | Right | 6' 1" | 170 lbs | - |
| Simmons, Forest | CF | Vancouver Grey Wolves | 32 | 10/30/1987 | Oakland | USA | Right | Left | 5' 11" | 200 lbs | $3,600,000 |
| Smith, Chris | 1B | Chicago Gold Sox | 31 | 05/02/1988 | Little Elm | USA | Right | Right | 6' 1" | 245 lbs | $2,900,000 |
| Smith, Paul | 3B | Rocky Mountain Nuggets | 26 | 02/04/1993 | Wrightsboro | USA | Right | Right | 6' 2" | 210 lbs | $280,000 |
| Snel, Cor | MR | Atlanta Smoke | 18 | 10/15/2001 | Tera Kora | ANT | Right | Right | 6' 2" | 185 lbs | - |
| Snyder, Carl | MR | Rocky Mountain Nuggets | 30 | 07/07/1989 | Los Angeles | USA | Right | Right | 6' 0" | 205 lbs | $430,000 |
| Solís, Alonso | SS | Philadephia 1776 BC | 19 | 10/29/2000 | Cabudare | VEN | Switch | Right | 6' 1" | 180 lbs | - |
| Solís, Fernando | SP | Rocky Mountain Nuggets | 20 | 11/16/1999 | Barahona | DOM | Right | Right | 6' 8" | 215 lbs | - |
| Souza, Ramón | LF | Athletic Club KC | 26 | 08/26/1993 | Craigsville | USA | Right | Right | 6' 0" | 200 lbs | $4,500,000 |
| Spear, Keith | LF | Detroit Reapers | 29 | 07/19/1990 | Abbeville | USA | Left | Left | 5' 11" | 200 lbs | $2,800,000 |
| Staton, Cory | 3B | Athletic Club KC | 32 | 09/05/1987 | Newark | USA | Right | Right | 6' 0" | 205 lbs | $2,800,000 |
| Stoops, Gijs | SP | Philadephia 1776 BC | 19 | 09/29/2000 | Nort Salinja | ANT | Right | Right | 6' 4" | 185 lbs | - |
| Strawson, Allan | SP | New Amsterdam Republics | 23 | 07/30/1996 | Green Valley | USA | Left | Left | 6' 3" | 200 lbs | $280,000 |
| Strong, Dave | MR | Wizarding AC Ravenclaws | 35 | 05/28/1984 | Yakima | USA | Right | Right | 6' 7" | 250 lbs | $13,800,000 |
| Sun, Decheng | MR | New Amsterdam Republics | 25 | 09/25/1994 | Taichung | TPE | Right | Right | 6' 1" | 205 lbs | $280,000 |
| Sunter, Bertrand | 1B | Vancouver Grey Wolves | 30 | 06/11/1989 | Kingston | JAM | Right | Right | 6' 4" | 255 lbs | $2,000,000 |
| Sutton, Cale | CF | Chicago Gold Sox | 25 | 11/29/1994 | Parole | USA | Right | Left | 6' 0" | 205 lbs | $7,500,000 |
| Suzuki, Eiji | 2B | Detroit Reapers | 34 | 12/03/1985 | Fukuoka | JPN | Switch | Right | 6' 0" | 200 lbs | $15,250,000 |
| Sylvester, Terry | LF | Las Vegas Flamingos | 26 | 10/01/1993 | Montgomery Township | USA | Right | Right | 6' 0" | 190 lbs | $2,510,000 |
