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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakamoto, Toshitsugu | LF | Lone Star BC | 27 | 02/20/1989 | Kumamoto | JPN | Right | Right | 6' 4" | 230 lbs | $6,295,000 |
| Salaedo, Pancho | 2B | Jacksonville Sharks | 16 | 12/19/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 175 lbs | - |
| Salas, Ramón | MR | Lone Star BC | 26 | 12/03/1989 | Las Cumbres | PAN | Left | Right | 6' 2" | 220 lbs | $280,000 |
| Salazar, Mike | MR | Capital District Red Knights | 24 | 05/27/1992 | Irving | USA | Right | Right | 6' 1" | 195 lbs | $290,000 |
| Salazar, Ramiro | CF | Oakland Oaks | 22 | 09/10/1994 | Memphis | USA | Switch | Right | 6' 0" | 190 lbs | $1,500,000 |
| Salazar, Ricardo | 3B | Jacksonville Sharks | 34 | 09/02/1982 | Centerville | USA | Right | Right | 6' 0" | 220 lbs | $1,555,000 |
| Salinas, Alberto | MR | Chicago Hawks | 31 | 03/01/1985 | Kent | USA | Right | Right | 6' 2" | 220 lbs | $2,650,000 |
| Salinas, José | MR | Kingston Township Legion 9 | 25 | 01/04/1991 | Santo Domingo | DOM | Right | Right | 6' 3" | 215 lbs | $290,000 |
| Sánchez, António | CF | Columbus Tidal Waves | 17 | 02/17/1999 | Ramón Santana | DOM | Right | Right | 6' 4" | 190 lbs | - |
| Sánchez, David | SS | Panama City Piranhas | 16 | 11/30/1999 | Santo Domingo | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sánchez, José | CL | SC Storm | 31 | 05/29/1985 | Santo Domingo | DOM | Right | Right | 6' 3" | 220 lbs | $1,500,000 |
| Sánchez, Juan | C | Thunder Bay Lumberjacks | 25 | 11/19/1990 | Valencia | VEN | Switch | Right | 6' 3" | 240 lbs | $12,285,000 |
| Sánchez, Juan | 3B | Jacksonville Sharks | 32 | 12/02/1983 | Dajabón | DOM | Right | Right | 6' 2" | 215 lbs | $2,160,000 |
| Sánchez, Pedro | 3B | Oakland Oaks | 25 | 01/21/1991 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 205 lbs | $190,000 |
| Sand, Doug | CL | Wizarding AC Ravenclaws | 26 | 06/13/1990 | Lake Junaluska | USA | Right | Right | 6' 0" | 205 lbs | $294,000 |
| Sandoval, José | SP | Oakland Oaks | 17 | 04/05/1999 | Santo Domingo | DOM | Left | Left | 6' 8" | 200 lbs | - |
| Sandoval, Juan | C | SC Storm | 16 | 05/14/2000 | Azua | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Santana, António | C | Wizarding AC Ravenclaws | 27 | 02/07/1989 | Rexburg | USA | Right | Right | 6' 0" | 210 lbs | $294,000 |
| Savary, Wilfrid | RF | Jacksonville Sharks | 31 | 04/18/1985 | Hamilton | CAN | Left | Left | 6' 5" | 235 lbs | $3,000,000 |
| Sawallisch, Han | MR | Toledo Titans | 26 | 11/02/1989 | Zweibrücken | GER | Left | Left | 6' 0" | 195 lbs | $1,700,000 |
| Schroeder, Derek | 2B | Panama City Piranhas | 26 | 06/12/1990 | Dallas | USA | Right | Right | 5' 11" | 195 lbs | $290,000 |
| Scott, Lindsay | C | Oakland Oaks | 23 | 12/12/1992 | Houston | USA | Right | Right | 6' 0" | 215 lbs | $285,000 |
| Scott, Peter | MR | Wizarding AC Ravenclaws | 29 | 09/27/1987 | New York | USA | Right | Right | 5' 10" | 200 lbs | $4,000,000 |
| Shaffer, Roger | RF | Toledo Titans | 30 | 01/03/1986 | St. Louis | USA | Left | Left | 6' 2" | 210 lbs | $8,240,000 |
| Sharp, Jeff | CF | Toledo Titans | 29 | 07/03/1987 | Los Angeles | USA | Left | Left | 6' 0" | 210 lbs | $2,180,000 |
| Shoemaker, Kane | MR | Wizarding AC Ravenclaws | 34 | 08/13/1982 | Houston | USA | Left | Left | 5' 11" | 200 lbs | $825,000 |
| Silva, Edward | MR | Houston 1837 Colt .45s | 31 | 01/12/1985 | Nelsonville | USA | Right | Right | 5' 9" | 180 lbs | $1,100,000 |
| Smith, Royce | SS | Kingston Township Legion 9 | 32 | 09/13/1984 | Pharr | USA | Left | Right | 6' 0" | 195 lbs | $800,000 |
| Smith, Tom | SS | Lone Star BC | 26 | 09/11/1990 | Moline | USA | Left | Left | 6' 3" | 245 lbs | $280,000 |
| Soto, Jesús | C | Kingston Township Legion 9 | 17 | 07/31/1999 | Santiago | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Stark, Tim | SP | Thunder Bay Lumberjacks | 33 | 12/12/1982 | Lafayette | USA | Right | Right | 6' 6" | 235 lbs | $850,000 |
| Strong, Dave | SP | Wizarding AC Ravenclaws | 32 | 05/28/1984 | Yakima | USA | Right | Right | 6' 7" | 245 lbs | $10,400,000 |
| Suárez, Jorge | 1B | Toledo Titans | 16 | 04/25/2000 | Azua | DOM | Right | Right | 6' 3" | 215 lbs | - |
