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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Emílio | RF | Capitol District Templars | 22 | 11/24/1992 | Baltimore | USA | Left | Left | 5' 10" | 180 lbs | $8,000,000 |
| Salazar, Ricardo | 3B | Casper Ghosts | 32 | 09/02/1982 | Centerville | USA | Right | Right | 6' 0" | 215 lbs | $1,500,000 |
| Sánchez, José | CL | SC Storm | 29 | 05/29/1985 | Santo Domingo | DOM | Right | Right | 6' 3" | 215 lbs | $1,293,000 |
| Sánchez, Juan | C | Casper Ghosts | 24 | 11/19/1990 | Valencia | VEN | Switch | Right | 6' 3" | 230 lbs | $11,750,000 |
| Sánchez, Lorenzo | RF | Capitol District Templars | 31 | 03/20/1983 | Caracas | VEN | Right | Right | 6' 2" | 225 lbs | - |
| Scanlan, Danny | SS | Free Agent | 33 | 11/08/1981 | Cerritos | USA | Left | Right | 6' 1" | 215 lbs | - |
| Scott, Peter | MR | San Francisco Fog | 27 | 09/27/1987 | New York | USA | Right | Right | 5' 10" | 195 lbs | $3,000,000 |
| Senna, Aurélio | MR | Casper Ghosts | 29 | 02/10/1985 | San Cristóbal | VEN | Right | Right | 6' 3" | 220 lbs | $1,000,000 |
| Shankle, Jon | SP | Norfolk Cruisers | 21 | 07/20/1993 | Bonadelle Ranchos-Madera Ranchos | USA | Switch | Right | 6' 2" | 195 lbs | $280,000 |
| Shaw, Kent | MR | Free Agent | 37 | 05/24/1977 | Indianapolis | USA | Switch | Right | 6' 0" | 210 lbs | - |
| Shaw, Stu | SS | Rocky Mountain Bears | 19 | 03/16/1995 | West Orange | USA | Right | Right | 6' 1" | 180 lbs | - |
| Shoemaker, Kane | MR | San Francisco Fog | 32 | 08/13/1982 | Houston | USA | Left | Left | 5' 11" | 195 lbs | $825,000 |
| Silver, Mike | 1B | Casper Ghosts | 25 | 04/14/1989 | Duluth | USA | Left | Right | 6' 1" | 215 lbs | $15,000,000 |
| Simmons, Forest | CF | Capitol District Templars | 27 | 10/30/1987 | Oakland | USA | Right | Left | 5' 11" | 200 lbs | $5,680,000 |
| Simons, Chris | 3B | Tuscaloosa Tide | 36 | 05/04/1978 | Los Angeles | USA | Right | Right | 6' 0" | 215 lbs | $14,000,000 |
| Smith, Blake | SP | Free Agent | 31 | 09/25/1983 | Union | USA | Switch | Right | 5' 11" | 200 lbs | - |
| Smith, Royce | CF | Casper Ghosts | 30 | 09/13/1984 | Pharr | USA | Left | Right | 6' 0" | 200 lbs | $800,000 |
| Smith, Tom | 1B | Casper Ghosts | 24 | 09/11/1990 | Moline | USA | Left | Left | 6' 3" | 240 lbs | $950,000 |
| So Payo, Sandro | SP | San Francisco Fog | 23 | 02/12/1991 | Ciudad Guayana | VEN | Switch | Right | 6' 4" | 220 lbs | - |
| Spencer, Danny | 2B | Northern Virginia Retrievers | 30 | 09/03/1984 | Elkton | USA | Right | Right | 5' 11" | 200 lbs | $10,500,000 |
| Squillari, Baptiste | MR | Free Agent | 33 | 05/31/1981 | Cabimas | VEN | Switch | Right | 6' 0" | 205 lbs | - |
| Stark, Tim | SP | Casper Ghosts | 32 | 12/12/1982 | Lafayette | USA | Right | Right | 6' 6" | 235 lbs | $800,000 |
| Stevens, Karl | 2B | Capitol District Templars | 18 | 10/16/1996 | Riva | USA | Right | Right | 6' 0" | 185 lbs | - |
| Stevens, Randy | 1B | Free Agent | 25 | 04/26/1989 | Rochester Hills | USA | Left | Right | 6' 1" | 235 lbs | - |
| Stout, Todd | MR | Free Agent | 39 | 09/14/1975 | Chillicothe | USA | Switch | Right | 6' 2" | 225 lbs | - |
| Strong, Dave | SP | San Francisco Fog | 30 | 05/28/1984 | Yakima | USA | Right | Right | 6' 7" | 245 lbs | $9,200,000 |
| Sullivan, Bruce | SP | Tuscaloosa Tide | 31 | 01/17/1983 | San Jose | USA | Right | Right | 5' 8" | 170 lbs | $280,000 |
| Suto, Masaharu | SP | San Francisco Fog | 30 | 02/11/1984 | Osaka | JPN | Right | Right | 6' 2" | 210 lbs | $4,020,000 |
| Sylvester, Terry | CF | Norfolk Cruisers | 21 | 10/01/1993 | Montgomery Township | USA | Right | Right | 6' 0" | 170 lbs | $280,000 |
