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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saitoti, Amlak | SS | Montgomery Biscuits | 24 | 07/20/2006 | Kutlwanong | RSA | Left | Right | 6' 3" | 205 lbs | - |
| Salas, Joe | 1B | West Virginia Power | 23 | 06/10/2007 | Springfield | USA | Right | Right | 6' 2" | 210 lbs | - |
| Salas, Juan | LF | Salem Silver Souls | 21 | 01/15/2009 | Lake Mary | USA | Left | Left | 6' 3" | 190 lbs | - |
| Sánchez, Jesús | 1B | Free Agent | 26 | 10/25/2004 | San Pedro de Macorís | DOM | Right | Right | 6' 3" | 235 lbs | - |
| Sánchez, Lúcio | 1B | Free Agent | 25 | 02/27/2005 | Brooklyn | USA | Right | Left | 6' 0" | 210 lbs | - |
| Sanders, Richard | 2B | Free Agent | 31 | 06/28/1999 | Forestville | USA | Right | Right | 6' 4" | 250 lbs | - |
| Sandoval, Alberto | SS | Salem Silver Souls | 25 | 09/14/2005 | Sabana de la Mar | DOM | Switch | Right | 6' 2" | 210 lbs | - |
| Santana, Ramiro | SS | Gainesville Guidos | 24 | 02/23/2006 | Barrancabermeja | COL | Right | Right | 6' 1" | 190 lbs | - |
| Sawyer, Dave | 2B | Montgomery Biscuits | 23 | 06/14/2007 | New York | USA | Right | Right | 6' 1" | 180 lbs | - |
| Sawyer, Richie | 3B | Beaumont Roughnecks | 23 | 03/22/2007 | Saint Paul | USA | Right | Right | 6' 1" | 190 lbs | - |
| Schneider, Bob | RP | Key West Barracudas | 28 | 10/23/2002 | Queens | USA | Right | Right | 6' 2" | 205 lbs | - |
| Schroeder, Phil | RP | Free Agent | 30 | 12/20/2000 | Laredo | USA | Left | Right | 6' 0" | 225 lbs | - |
| Scott, Albert | RP | West Virginia Power | 24 | 09/12/2006 | DeKalb | USA | Right | Right | 6' 4" | 205 lbs | - |
| Scott, Nick | RF | Salem Silver Souls | 28 | 05/03/2002 | Royalston | USA | Left | Left | 6' 1" | 195 lbs | - |
| Segura, Stephen | 2B | Wichita Wranglers | 22 | 08/21/2008 | Winthrop | USA | Right | Right | 6' 1" | 180 lbs | - |
| Senteno, Javier | RF | Memphis Blues | 25 | 12/19/2005 | Santo Domingo | DOM | Right | Right | 5' 10" | 185 lbs | - |
| Shelton, Vaughan | SS | West Virginia Power | 25 | 11/23/2005 | Santa Fe | USA | Right | Right | 6' 1" | 195 lbs | - |
| Shirley, Brent | SP | Montgomery Biscuits | 22 | 05/16/2008 | Brent | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sierra, Ramiro | SP | BlackIron Dragons | 25 | 06/20/2005 | La Romana | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Silva, Roderick | 1B | BlackIron Dragons | 25 | 10/28/2005 | Oklahoma City | USA | Right | Right | 6' 2" | 210 lbs | - |
| Sims, Tristan | SS | Wichita Wranglers | 23 | 06/08/2007 | Palatine | USA | Left | Right | 5' 8" | 180 lbs | - |
| Smith, John | 3B | Key West Barracudas | 27 | 11/19/2003 | Staten Island | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smith, Steve | 1B | Salem Silver Souls | 22 | 01/15/2008 | Jennings | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Xavier | RF | Free Agent | 25 | 03/18/2005 | Harrisburg | USA | Left | Left | 6' 5" | 225 lbs | - |
| Snyder, Calvin | RP | Montgomery Biscuits | 27 | 10/21/2003 | New Orleans | USA | Right | Right | 5' 10" | 180 lbs | - |
| Solíz, Francisco | SP | Salem Silver Souls | 21 | 10/22/2009 | Campo Grande | BRA | Right | Right | 5' 9" | 160 lbs | - |
| Sosa, Ron | SP | Wichita Wranglers | 22 | 04/26/2008 | Cicero | USA | Left | Left | 6' 0" | 180 lbs | - |
| Stafford, Will | SS | West Virginia Power | 26 | 11/05/2004 | New York | USA | Right | Right | 6' 2" | 200 lbs | - |
| Steele, Clancy | RP | Montgomery Biscuits | 27 | 10/12/2003 | Rolling Meadows | USA | Right | Right | 6' 7" | 235 lbs | - |
| Steele, Jared | RP | Montgomery Biscuits | 23 | 01/25/2007 | Hoover | USA | Left | Left | 6' 0" | 180 lbs | - |
| Stephenson, Bill | RF | Free Agent | 26 | 12/05/2004 | Obion | USA | Left | Left | 6' 0" | 200 lbs | - |
| Sterling, Vernon | 1B | Free Agent | 27 | 10/19/2003 | Euclid | USA | Right | Right | 6' 2" | 235 lbs | - |
| Stewart, Michael | RP | West Virginia Power | 26 | 05/29/2004 | Palo Alto | USA | Left | Left | 6' 3" | 200 lbs | - |
| Storms, Joe | LF | Memphis Blues | 24 | 08/24/2006 | Springfield | USA | Left | Left | 6' 5" | 225 lbs | - |
| Stuart, Ted | RP | Santa Fe Diablos | 26 | 08/16/2004 | Denver | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sutcliffe, Hal | SP | Santa Fe Diablos | 20 | 01/12/2010 | Innisfail | AUS | Right | Right | 6' 1" | 175 lbs | - |
