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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Esteban | 3B | Free Agent | 28 | 05/02/2000 | New York | USA | Right | Right | 6' 3" | 245 lbs | - |
| Sánchez, Albert | SP | Rio Grande Rattlesnake | 25 | 10/29/2003 | The Bronx | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sánchez, Rafael | RP | Intercourse Amish | 20 | 01/20/2008 | Acarigua | VEN | Left | Right | 6' 7" | 205 lbs | - |
| Sánchez, Ramón | RP | Free Agent | 30 | 09/13/1998 | Barquisimeto | VEN | Right | Right | 6' 0" | 230 lbs | - |
| Sanders, Sloan | SP | Intercourse Amish | 24 | 11/22/2004 | New York | USA | Right | Left | 6' 0" | 190 lbs | - |
| Santiago, Sixto | CL | Intercourse Amish | 23 | 07/08/2005 | Barahona | DOM | Left | Right | 6' 7" | 220 lbs | - |
| Santos, Guillermo | CF | Wilmington Rebels | 22 | 06/05/2006 | La Victoria | VEN | Left | Left | 6' 0" | 185 lbs | - |
| Serrano, Ángel | LF | Butler White Sox | 21 | 03/16/2007 | Calabozo | VEN | Right | Right | 6' 7" | 230 lbs | - |
| Shelton, Don | RP | Intercourse Amish | 26 | 08/22/2002 | Winter Haven | USA | Right | Right | 6' 0" | 225 lbs | - |
| Short, Justin | RP | Intercourse Amish | 25 | 07/29/2003 | Urbana | USA | Left | Left | 6' 1" | 190 lbs | - |
| Silva, Andrés | 1B | Butler White Sox | 23 | 08/15/2005 | Cagua | VEN | Right | Left | 6' 2" | 215 lbs | - |
| Silva, Jorge | C | Newark Bulldogs | 21 | 08/02/2007 | San Agustín | COL | Right | Right | 6' 1" | 205 lbs | - |
| Silva, Juan | RP | Butler White Sox | 24 | 07/17/2004 | Santo Domingo | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Silva, Luis | RP | Reading Rainbows | 28 | 06/07/2000 | Santa Maria | USA | Right | Right | 6' 5" | 230 lbs | - |
| Silva, Manny | SP | Rio Grande Rattlesnake | 26 | 01/03/2002 | Denton | USA | Left | Right | 6' 0" | 180 lbs | - |
| Silva, Manuel | SP | Wilmington Rebels | 22 | 07/25/2006 | San Pedro de Macorís | DOM | Right | Right | 5' 10" | 170 lbs | - |
| Skinner, Michael | RF | Newark Bulldogs | 26 | 11/01/2002 | Winchester | USA | Right | Right | 5' 10" | 185 lbs | - |
| Smith, Louis | C | Reading Rainbows | 28 | 09/10/2000 | Cullman | USA | Right | Right | 6' 1" | 240 lbs | - |
| Snow, Neil | SP | Rio Grande Rattlesnake | 26 | 03/19/2002 | The Bronx | USA | Right | Right | 6' 2" | 205 lbs | - |
| Solís, Mario | RF | Buffalo LightSabres | 25 | 07/15/2003 | Fredonia | USA | Right | Left | 6' 0" | 190 lbs | - |
| Sparks, Cam | RP | Minnesota ManBearPigs | 26 | 09/10/2002 | Minneapolis | USA | Left | Right | 6' 0" | 175 lbs | - |
| Stevenson, Matt | RP | Minnesota ManBearPigs | 26 | 05/10/2002 | Memphis | USA | Right | Right | 5' 10" | 195 lbs | - |
| Stolk, Huub | 2B | Buffalo LightSabres | 24 | 08/19/2004 | Cul De Sac | ANT | Right | Right | 5' 10" | 180 lbs | - |
| Stout, Gabriel | 2B | Intercourse Amish | 28 | 10/25/2000 | Birdsboro | USA | Right | Right | 6' 0" | 185 lbs | - |
| Suarze, David | SS | Rio Grande Rattlesnake | 25 | 11/22/2003 | San Miguelito | PAN | Right | Right | 6' 1" | 195 lbs | - |
| Sullivan, Seth | SS | Wilmington Rebels | 19 | 05/19/2009 | Jacksonville | USA | Left | Right | 6' 3" | 195 lbs | - |
