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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Edwards, Ron | 1B | Kansas City Kings | 24 | 03/28/2002 | Tyngsborough | USA | Switch | Right | 6' 0" | 210 lbs | - |
| Elías, Juan | SP | Niagara Falls Frenzy | 19 | 03/03/2007 | Duvergé | DOM | Right | Right | 6' 7" | 200 lbs | - |
| Elliott, Michael | RF | San Francisco Bandits | 25 | 04/18/2001 | Bastrop | USA | Right | Right | 6' 0" | 205 lbs | $2,940,000 |
| Émond, Samuel | SP | Hendersonville Hitmen | 30 | 12/07/1996 | Ottawa | CAN | Right | Right | 6' 4" | 295 lbs | $6,500,000 |
| Encarnación, Miguel | 2B | Kalamazoo Royale with Cheese | 31 | 03/14/1995 | Tucupita | VEN | Right | Right | 5' 9" | 180 lbs | $3,200,000 |
| Endo, Yajirobei | RP | Springfield Stars | 31 | 08/04/1995 | Komaki | JPN | Right | Right | 6' 6" | 215 lbs | $1,800,000 |
| Entwistle, Erwin | SP | Los Cabos Cartel | 23 | 07/23/2003 | Oranjestad | ARU | Left | Right | 6' 2" | 190 lbs | - |
| Erickson, Anthony | SP | Springfield Stars | 25 | 08/18/2001 | Bel Aire | USA | Left | Left | 6' 0" | 195 lbs | $500,000 |
| Erickson, Jason | C | Jersey Shore D-Bags | 26 | 03/15/2000 | Cedar Rapids | USA | Right | Right | 5' 11" | 235 lbs | $400,000 |
| Escamilla, Alfredo | SP | Kansas City Kings | 18 | 05/03/2008 | Chihuahua | MEX | Right | Right | 6' 1" | 180 lbs | - |
| Escobar, Albert | CF | Baffin Island Beavers | 16 | 04/15/2010 | Utuado | PUR | Right | Right | 6' 4" | 195 lbs | - |
| Escobar, Carlos | SS | Seattle Pikes | 17 | 11/09/2009 | Panama | PAN | Right | Right | 6' 3" | 180 lbs | - |
| Escobar, Cristián | CL | Seattle Pikes | 28 | 11/26/1998 | Guanajuato | MEX | Left | Left | 6' 3" | 265 lbs | $6,060,000 |
| Escobedo, Carlos | SP | St. Louis Browns | 16 | 02/03/2010 | Bogota | COL | Left | Right | 6' 1" | 170 lbs | - |
| Escobedo, Gerardo | 3B | Los Cabos Cartel | 29 | 08/29/1997 | San Juan | PUR | Right | Right | 6' 3" | 220 lbs | $1,800,000 |
| Esparza, José | RF | Free Agent | 34 | 03/24/1992 | Bismarck | USA | Left | Left | 6' 2" | 190 lbs | - |
| Espinosa, Juan | CF | So Cal Henvy | 19 | 02/09/2007 | Barquisimeto | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Espinosa, Juan | SP | Madison Bombers | 25 | 08/23/2001 | Clarksville | USA | Left | Left | 6' 1" | 195 lbs | $400,000 |
| Espinosa, Máximo | SP | Irvine Gang Green | 17 | 09/28/2009 | Maracay | VEN | Switch | Right | 6' 0" | 165 lbs | - |
| Espinoza, Alfonso | SP | Irvine Gang Green | 21 | 08/04/2005 | Maracaibo | VEN | Right | Right | 6' 5" | 190 lbs | - |
| Espinoza, Anselmo | SS | Houston Marshals | 17 | 10/09/2009 | Guisa | CUB | Right | Right | 6' 2" | 180 lbs | - |
| Espinoza, Jaime | RP | Pocatello Boccabellas | 25 | 01/24/2001 | Brick | USA | Right | Right | 6' 1" | 225 lbs | $750,000 |
| Espinoza, Javier | SS | Maui Tropics | 28 | 04/29/1998 | Santo Domingo | DOM | Left | Right | 6' 4" | 230 lbs | $800,000 |
| Espinoza, Jesús | 3B | Maui Tropics | 25 | 04/30/2001 | Maracaibo | VEN | Right | Right | 6' 0" | 195 lbs | $7,670,000 |
| Espinoza, Rubén | 1B | Vista Panthers | 18 | 02/16/2008 | Santiago | DOM | Switch | Right | 6' 7" | 245 lbs | - |
| Estrada, Ángel | RF | So Cal Henvy | 20 | 11/23/2006 | San Miguelito | PAN | Switch | Right | 6' 2" | 185 lbs | - |
| Estrada, Ángel | SP | Pocatello Boccabellas | 19 | 11/21/2007 | Villa Jaragua | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Estrada, Augusto | SS | Houston Marshals | 16 | 03/20/2010 | Maracay | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Estrada, Ramón | RP | Austin River Sharks | 30 | 11/22/1996 | Canóvanas | PUR | Right | Right | 6' 5" | 275 lbs | $7,400,000 |
| Evans, Tommy | SS | St. Louis Browns | 27 | 11/27/1999 | Santa Clarita | USA | Left | Right | 6' 0" | 220 lbs | $650,000 |
