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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Jorge | SP | Montgomery Biscuits | 28 | 11/26/1993 | Jiguaní | CUB | Right | Right | 6' 6" | 205 lbs | - |
| Sánchez, Esteban | 3B | BlackIron Dragons | 29 | 11/25/1992 | Ocumare del Tuy | VEN | Switch | Right | 6' 1" | 220 lbs | - |
| Sánchez, Marcel | SP | Free Agent | 27 | 06/26/1994 | Monrovia | USA | Right | Right | 6' 4" | 245 lbs | - |
| Sánchez, Orlando | RF | Montgomery Biscuits | 27 | 05/20/1994 | Caguas | PUR | Right | Right | 5' 10" | 180 lbs | - |
| Sanders, Lance | MR | Gainesville Guidos | 25 | 10/27/1996 | Jacksonville | USA | Right | Right | 6' 6" | 230 lbs | - |
| Sanders, Mark | SP | West Virginia Power | 27 | 10/20/1994 | Worcester | USA | Switch | Right | 6' 3" | 260 lbs | - |
| Santana, Pedro | SP | Key West Barracudas | 26 | 03/24/1995 | Oldsmar | USA | Left | Left | 6' 1" | 225 lbs | - |
| Schmitt, Josh | SP | Santa Fe Diablos | 26 | 12/01/1995 | La Habra Heights | USA | Right | Right | 6' 3" | 235 lbs | - |
| Schultz, Michael | SP | Key West Barracudas | 27 | 08/23/1994 | Cincinnati | USA | Right | Right | 6' 1" | 220 lbs | - |
| Schultz, Ralph | C | BlackIron Dragons | 27 | 04/15/1994 | West Hattiesburg | USA | Left | Right | 6' 2" | 195 lbs | - |
| Scott, Sherman | 2B | Santa Fe Diablos | 25 | 02/02/1996 | Apple Valley | USA | Left | Right | 6' 1" | 220 lbs | - |
| Shaffer, Francis | 3B | West Palm Reds | 22 | 02/12/1999 | Detroit | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Sheppard, David | MR | Santa Fe Diablos | 23 | 12/20/1998 | Mounds View | USA | Right | Right | 6' 1" | 250 lbs | - |
| Shimizu, Masayuki | SP | Wichita Wranglers | 25 | 03/10/1996 | Kitakyushu | JPN | Right | Right | 6' 1" | 250 lbs | - |
| Shirley, Eddie | RF | BlackIron Dragons | 23 | 05/12/1998 | Hoffman Estates | USA | Right | Left | 5' 8" | 185 lbs | - |
| Silva, Manuel | MR | Free Agent | 27 | 07/10/1994 | Myrtle Grove | USA | Right | Right | 6' 11" | 260 lbs | - |
| Simms, Jayson | MR | BlackIron Dragons | 22 | 02/17/1999 | Athens | USA | Right | Right | 6' 0" | 225 lbs | - |
| Sims, Brad | MR | Wichita Wranglers | 25 | 05/08/1996 | San Antonio | USA | Left | Left | 6' 6" | 225 lbs | - |
| Sims, Ed | 2B | BlackIron Dragons | 23 | 01/30/1998 | Los Angeles | USA | Right | Right | 6' 3" | 190 lbs | - |
| Sin, Kang-il | SS | Gainesville Guidos | 26 | 05/26/1995 | Pusan | KOR | Right | Right | 6' 2" | 185 lbs | - |
| Skinner, Kenny | MR | West Virginia Power | 22 | 03/30/1999 | Newport News | USA | Left | Right | 6' 0" | 210 lbs | - |
| Smith, Bill | RF | West Palm Reds | 22 | 01/10/1999 | Indianapolis | USA | Left | Left | 6' 5" | 170 lbs | - |
| Smith, Collin | LF | Montgomery Biscuits | 23 | 06/29/1998 | Columbus | USA | Right | Right | 5' 8" | 180 lbs | - |
| Smith, Pete | RF | Montgomery Biscuits | 24 | 03/26/1997 | Dallas | USA | Right | Right | 6' 1" | 205 lbs | - |
| Smith, Todd | CF | West Palm Reds | 25 | 06/12/1996 | Bismarck | USA | Switch | Right | 6' 0" | 205 lbs | - |
| Snyder, Mal | 1B | BlackIron Dragons | 28 | 11/09/1993 | New York | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sterling, Will | C | Wichita Wranglers | 25 | 12/28/1996 | New York | USA | Right | Right | 5' 8" | 190 lbs | - |
| Stoffels, Luther | RF | Key West Barracudas | 25 | 05/29/1996 | Ballrechten-Dottingen | GER | Right | Right | 5' 10" | 180 lbs | - |
| Stover, Leroy | 2B | Santa Fe Diablos | 25 | 01/06/1996 | Cleveland | USA | Left | Right | 6' 0" | 210 lbs | - |
| Stroud, Benjamin | SP | Free Agent | 27 | 03/07/1994 | Brooklyn | USA | Left | Left | 6' 2" | 225 lbs | - |
| Suzuki, Toshikasu | CF | Gainesville Guidos | 27 | 09/16/1994 | Matsubara | JPN | Left | Right | 6' 3" | 175 lbs | - |
