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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Eager, Ron | SP | Austin River Sharks | 32 | 12/15/1989 | Winnipeg | CAN | Switch | Right | 6' 2" | 200 lbs | $6,000,000 |
| Edgar, Jim | 2B | Free Agent | 27 | 05/10/1994 | Billings | USA | Right | Right | 6' 1" | 195 lbs | - |
| Edwards, David | MR | Springfield Stars | 37 | 05/03/1984 | La Grange | USA | Right | Right | 6' 2" | 215 lbs | $1,000,000 |
| Edwards, Gordon | SS | Free Agent | 32 | 11/19/1989 | Glendale | USA | Left | Right | 6' 1" | 195 lbs | - |
| Edwards, Mike | CF | Free Agent | 22 | 08/18/1999 | Guaynabo | PUR | Right | Right | 6' 2" | 175 lbs | - |
| Ellis, Art | SP | Free Agent | 36 | 11/06/1985 | El Cajon | USA | Right | Right | 6' 1" | 210 lbs | - |
| Émond, Samuel | SP | Chicago Machine | 25 | 12/07/1996 | Ottawa | CAN | Right | Right | 6' 4" | 290 lbs | $8,750,000 |
| Encarnación, Manuel | SP | Kansas City Kings | 16 | 01/10/2005 | Santiago | DOM | Left | Left | 6' 5" | 190 lbs | - |
| Encarnación, Miguel | SS | St. Louis Browns | 26 | 03/14/1995 | Tucupita | VEN | Right | Right | 5' 9" | 185 lbs | $1,500,000 |
| Endo, Yajirobei | SP | Reno Cards | 26 | 08/04/1995 | Komaki | JPN | Right | Right | 6' 6" | 225 lbs | $3,600,000 |
| Entwistle, Erwin | SP | Los Cabos Cartel | 18 | 07/23/2003 | Oranjestad | ARU | Left | Right | 6' 2" | 180 lbs | - |
| Escobar, Cristián | MR | Seattle Pikes | 23 | 11/26/1998 | Guanajuato | MEX | Left | Left | 6' 3" | 245 lbs | $400,000 |
| Escobedo, Gerardo | 3B | St Charles Sheens | 24 | 08/29/1997 | San Juan | PUR | Right | Right | 6' 3" | 220 lbs | $5,800,000 |
| Esparza, José | CF | Vista Panthers | 29 | 03/24/1992 | Bismarck | USA | Left | Left | 6' 2" | 185 lbs | $3,800,000 |
| Esparza, José | CF | Jersey Shore D-Bags | 17 | 11/28/2004 | Mao | DOM | Right | Right | 5' 9" | 160 lbs | - |
| Espinoza, Luis | CF | Chicago Machine | 25 | 12/29/1996 | Tapachula | MEX | Left | Left | 6' 1" | 195 lbs | $400,000 |
| Estes, Erik | MR | Los Cabos Cartel | 32 | 06/27/1989 | Murrieta Hot Springs | USA | Right | Right | 6' 2" | 220 lbs | $950,000 |
| Estes, Wayne | CF | Free Agent | 28 | 02/10/1993 | Oakville | USA | Right | Right | 6' 0" | 205 lbs | - |
| Estrada, Manny | MR | Free Agent | 35 | 08/14/1986 | Jones Creek | USA | Right | Right | 6' 1" | 200 lbs | - |
| Estrada, Tomás | RF | St Charles Sheens | 25 | 12/25/1996 | Mexico City | MEX | Right | Right | 5' 9" | 170 lbs | $400,000 |
| Estrada, Tony | SS | Orlando Calrissian | 17 | 07/29/2004 | San Fernando | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Estreito, José | SS | Hendersonville Hitmen | 16 | 07/10/2005 | Ciudad Guayana | VEN | Switch | Right | 6' 4" | 185 lbs | - |
