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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Vincente | RF | Nashua Redlegs | 21 | 02/08/1999 | Santiago | DOM | Left | Left | 5' 10" | 210 lbs | - |
| Salcido, Ricardo | MR | Free Agent | 17 | 08/05/2003 | Cotuí | DOM | Switch | Right | 6' 1" | 170 lbs | - |
| Sánchez, José | 1B | Tolland Singrays | 23 | 08/28/1997 | Rancho Cordova | USA | Right | Right | 6' 0" | 205 lbs | - |
| Sánchez, Sergio | 1B | Free Agent | 24 | 08/25/1996 | San Juan de la Maguana | DOM | Switch | Right | 6' 0" | 185 lbs | - |
| Sanders, Richard | 2B | Nantucket Orcas | 21 | 06/28/1999 | Forestville | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sandoval, Ramón | RF | Louisville Rockets | 21 | 06/24/1999 | Fresno | USA | Right | Right | 6' 2" | 200 lbs | - |
| Santos, Ricardo | 2B | Nantucket Orcas | 24 | 07/23/1996 | Caracas | VEN | Right | Right | 5' 10" | 185 lbs | - |
| Sasaki, Toyokazu | SP | Athens Assassins | 24 | 07/13/1996 | Oyabe | JPN | Left | Left | 6' 1" | 220 lbs | - |
| Saucedo, Oliver | 3B | Nantucket Orcas | 24 | 07/15/1996 | Claremont | USA | Right | Right | 6' 1" | 205 lbs | - |
| Schmidt, Paul | RF | Free Agent | 21 | 08/10/1999 | Albuquerque | USA | Left | Left | 6' 3" | 205 lbs | - |
| Schroeder, Phil | MR | Louisville Rockets | 20 | 12/20/2000 | Laredo | USA | Left | Right | 6' 0" | 210 lbs | - |
| Scott, Joe | MR | Louisville Rockets | 21 | 12/28/1999 | New York | USA | Left | Left | 6' 1" | 210 lbs | - |
| Sears, John | 1B | Free Agent | 23 | 02/17/1997 | Malden | USA | Left | Left | 6' 0" | 185 lbs | - |
| Serrano, Roberto | SP | Free Agent | 29 | 02/27/1991 | San Juan de la Maguana | DOM | Switch | Right | 5' 9" | 205 lbs | - |
| Seymour, Vincent | 2B | Free Agent | 24 | 10/29/1996 | Glassboro | USA | Right | Right | 6' 1" | 210 lbs | - |
| Shaffer, Francis | 3B | Louisville Rockets | 21 | 02/12/1999 | Detroit | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Sheehan, Davis | SP | Savannah Hogs | 23 | 02/07/1997 | Phoenix | USA | Right | Right | 5' 8" | 215 lbs | - |
| Simpson, David | MR | Montgomery Grey Sox | 21 | 04/13/1999 | Norman | USA | Right | Right | 6' 4" | 230 lbs | - |
| Sims, Ed | 2B | Athens Assassins | 22 | 01/30/1998 | Los Angeles | USA | Right | Right | 6' 3" | 180 lbs | - |
| Small, Teddy | 3B | Savannah Hogs | 24 | 12/17/1996 | Bloomingdale | USA | Right | Right | 5' 10" | 170 lbs | - |
| Smith, Bob | 1B | Savannah Hogs | 23 | 10/01/1997 | Somerville | USA | Left | Left | 6' 4" | 205 lbs | - |
| Smith, Ken | 1B | Free Agent | 25 | 09/14/1995 | Warwick | USA | Left | Left | 5' 9" | 185 lbs | - |
| Smith, Matt | 3B | Pensacola Pilots | 21 | 04/30/1999 | Richmond | USA | Left | Right | 6' 1" | 190 lbs | - |
| Smith, Pete | RF | Montgomery Grey Sox | 23 | 03/26/1997 | Dallas | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smith, Ryan | LF | Free Agent | 26 | 10/19/1994 | New York | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Snow, Dan | 3B | Free Agent | 26 | 07/21/1994 | Winnipeg | CAN | Right | Right | 5' 8" | 180 lbs | - |
| Snyder, Ernest | 1B | Free Agent | 20 | 02/17/2000 | Morrisville in Greene County | USA | Left | Left | 6' 2" | 200 lbs | - |
| Sosa, Jesús | LF | Montgomery Grey Sox | 22 | 07/28/1998 | Mérida | MEX | Right | Right | 6' 0" | 165 lbs | - |
| Spencer, Kendrick | SP | Tolland Singrays | 23 | 12/05/1997 | Eagleville | USA | Left | Left | 6' 3" | 215 lbs | - |
| Suárez, Sergio | MR | Louisville Rockets | 21 | 12/10/1999 | La Follette | USA | Left | Right | 5' 10" | 220 lbs | - |
| Sweeney, Robby | LF | State College Spikes | 21 | 05/29/1999 | New York | USA | Right | Left | 6' 3" | 200 lbs | - |
