| 12/31/2018 | ||||||
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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
| Sakurai, Rikiya | CL | Springfield Simpsons | 26 | 10/02/1992 | Fukuoka | JPN | Right | Right | 6' 5" | 250 lbs | - |
| Salazar, Juan | LF | Mt Pleasant Bearcats | 32 | 03/21/1986 | Wayne | USA | Right | Right | 6' 0" | 177 lbs | - |
| Sammons, Bernie | MR | Reading Rainbows | 25 | 03/16/1993 | Montgomery | USA | Right | Right | 6' 2" | 215 lbs | - |
| Sánchez, Ramón | CF | Buffalo LightSabres | 24 | 05/29/1994 | Pinar del Rio | CUB | Left | Left | 6' 1" | 165 lbs | - |
| Sandoval, Júlio | MR | Newark Bulldogs | 23 | 10/19/1995 | Santo Domingo | DOM | Switch | Right | 6' 1" | 230 lbs | - |
| Sato, Hiroaki | SS | Springfield Simpsons | 22 | 10/16/1996 | Yoro | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Schultz, Justin | 1B | Springfield Simpsons | 21 | 08/09/1997 | Chicago | USA | Right | Right | 6' 0" | 200 lbs | - |
| Segura, Jesús | 3B | Reading Rainbows | 23 | 01/23/1995 | Ciudad Bolívar | VEN | Switch | Right | 6' 3" | 200 lbs | - |
| Seif, Hicham | SP | Springfield Simpsons | 23 | 09/24/1995 | Busia | KEN | Left | Left | 5' 9" | 225 lbs | - |
| Serrano, Juan | 3B | Buffalo LightSabres | 23 | 03/17/1995 | Ecatepec | MEX | Right | Right | 6' 0" | 185 lbs | - |
| Serrano, Roberto | LF | Reading Rainbows | 24 | 10/12/1994 | Santo Domingo | DOM | Switch | Right | 6' 6" | 160 lbs | - |
| Serrea, Álex | SP | Buffalo LightSabres | 23 | 09/16/1995 | Camagüey | CUB | Right | Right | 6' 0" | 220 lbs | - |
| Shiu, Ki-tong | CL | Butler White Sox | 24 | 04/28/1994 | Kaohsiung | TPE | Right | Right | 5' 11" | 215 lbs | - |
| Simmons, Roger | 1B | Lima Oilers | 27 | 11/20/1991 | Seattle Hill-Silver Firs | USA | Left | Left | 6' 0" | 200 lbs | - |
| Simon, Cole | MR | Lima Oilers | 23 | 02/09/1995 | Las Vegas | USA | Right | Right | 6' 0" | 240 lbs | - |
| Solíz, Mario | MR | Mt Pleasant Bearcats | 23 | 05/25/1995 | Juigalpa | NCA | Right | Left | 6' 0" | 215 lbs | - |
| Sotelo, Carlos | SS | Wilmington Rebels | 22 | 10/13/1996 | Durango | MEX | Right | Right | 5' 11" | 210 lbs | - |
| Soto, Manuel | MR | Mt Pleasant Bearcats | 26 | 10/19/1992 | Beverly | USA | Left | Left | 6' 5" | 215 lbs | - |
| Spence, Daniel | C | Mt Pleasant Bearcats | 34 | 06/13/1984 | New York | USA | Switch | Right | 5' 9" | 180 lbs | - |
| Steele, Brad | MR | Reading Rainbows | 26 | 10/31/1992 | South Snyderville Basin | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stevens, Tom | CF | Butler White Sox | 24 | 08/13/1994 | Kent | USA | Switch | Right | 6' 0" | 175 lbs | - |
| Sugiyama, Nori | RF | Wilmington Rebels | 22 | 09/18/1996 | Gifu | JPN | Right | Right | 6' 2" | 190 lbs | - |
| Sugiyama, Tadakuni | C | Wilmington Rebels | 19 | 07/28/1999 | Koriyama | JPN | Right | Right | 6' 4" | 195 lbs | - |
