| 12/31/2018 | ||||||
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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
| Sáenz, Jorge | LF | Wichita Wranglers | 26 | 10/28/1992 | Oranjestad | ARU | Right | Right | 6' 0" | 190 lbs | - |
| Salazar, Luis | SP | Gainesville Guidos | 23 | 03/28/1995 | San Nicolas | CRC | Right | Right | 6' 0" | 195 lbs | - |
| Salgado, Juan | MR | Wichita Wranglers | 30 | 08/14/1988 | Martinsburg | USA | Left | Left | 6' 5" | 211 lbs | - |
| Salgado, Nelson | C | Free Agent | 24 | 06/03/1994 | Ponce | PUR | Right | Right | 5' 8" | 190 lbs | - |
| Salinas, Miguel | C | Gainesville Guidos | 21 | 04/07/1997 | Havana | CUB | Right | Right | 6' 1" | 195 lbs | - |
| Sánchez, Augusto | LF | BlackIron Dragons | 33 | 11/29/1985 | Spanish Lake | USA | Right | Right | 6' 2" | 182 lbs | - |
| Sánchez, Fernando | SP | West Palm Reds | 30 | 04/29/1988 | Duncan | USA | Switch | Right | 6' 3" | 223 lbs | - |
| Sánchez, Marcel | SP | Memphis Blues | 24 | 06/26/1994 | Monrovia | USA | Right | Right | 6' 4" | 235 lbs | - |
| Sánchez, Orlando | RF | Montgomery Biscuits | 24 | 05/20/1994 | Caguas | PUR | Right | Right | 5' 10" | 180 lbs | - |
| Sanders, Joe | RF | New Hampshire Fisher Cats | 27 | 08/19/1991 | Temecula | USA | Left | Left | 6' 5" | 209 lbs | - |
| Schneider, Errol | MR | Free Agent | 30 | 11/16/1988 | Santa Clarita | USA | Switch | Right | 6' 1" | 242 lbs | - |
| Schultz, Ralph | C | BlackIron Dragons | 24 | 04/15/1994 | West Hattiesburg | USA | Left | Right | 6' 2" | 190 lbs | - |
| Seccombe, Ron | SP | Memphis Blues | 23 | 01/22/1995 | Winooski | USA | Left | Left | 6' 2" | 215 lbs | - |
| Seymour, Abraham | MR | Santa Fe Diablos | 28 | 07/24/1990 | Pasadena | USA | Switch | Right | 6' 0" | 217 lbs | - |
| Shaw, Franklin | 2B | BlackIron Dragons | 23 | 05/14/1995 | Jacksonville | USA | Right | Right | 5' 11" | 185 lbs | - |
| Sheppard, Jim | CL | West Virginia Power | 23 | 12/29/1995 | Brantford | CAN | Left | Left | 5' 10" | 230 lbs | - |
| Sin, Kang-il | SS | Gainesville Guidos | 23 | 05/26/1995 | Pusan | KOR | Right | Right | 6' 2" | 175 lbs | - |
| Smith, Clifford | SP | Santa Fe Diablos | 23 | 05/25/1995 | Somerset | USA | Right | Right | 6' 3" | 265 lbs | - |
| Soriano, Enrique | 2B | Free Agent | 27 | 07/07/1991 | Santo Domingo | DOM | Left | Right | 5' 8" | 200 lbs | - |
| Soto, Víctor | MR | Santa Fe Diablos | 19 | 04/30/1999 | San Luis | CUB | Left | Left | 6' 8" | 255 lbs | - |
| Starr, Ed | 1B | Memphis Blues | 21 | 08/30/1997 | Chicago | USA | Right | Right | 5' 11" | 175 lbs | - |
| Stewart, Dean | LF | Wichita Wranglers | 29 | 01/21/1989 | Gulfport | USA | Left | Left | 6' 1" | 192 lbs | - |
| Stover, Leroy | 2B | Santa Fe Diablos | 22 | 01/06/1996 | Cleveland | USA | Left | Right | 6' 0" | 202 lbs | - |
| Suárez, Jesús | SP | Montgomery Biscuits | 24 | 06/03/1994 | Beavercreek | USA | Right | Right | 6' 3" | 220 lbs | $800,000 |
| Suzuki, Toshikasu | CF | Gainesville Guidos | 24 | 09/16/1994 | Matsubara | JPN | Left | Right | 6' 3" | 160 lbs | - |
