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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakata, Sotaro | C | Las Vegas Flamingos | 33 | 09/01/1998 | Sasebo | JPN | Right | Right | 6' 1" | 220 lbs | $9,000,000 |
| Salazar, Felipe | SP | Athletic Club KC | 17 | 08/10/2014 | Higüey | DOM | Switch | Right | 5' 11" | 165 lbs | - |
| Salazar, Miguel | SP | Thunder Bay Northern Lions BC | 17 | 10/11/2014 | Colón | CRC | Right | Right | 6' 1" | 170 lbs | - |
| Salgado, Ramón | SP | Rocky Mountain Nuggets | 16 | 01/10/2015 | Villa Vazquez | DOM | Switch | Right | 6' 0" | 165 lbs | - |
| Sánchez, Bartolo | SP | Athletic Club KC | 16 | 04/09/2015 | Chiguayante | CHI | Switch | Left | 6' 2" | 175 lbs | - |
| Sánchez, Carlos | 2B | Philadelphia 1776 BC | 31 | 11/07/2000 | Carolina | PUR | Switch | Right | 6' 0" | 220 lbs | $280,000 |
| Sánchez, Fernando | 1B | Wizarding Express | 28 | 08/12/2003 | La Romana | DOM | Switch | Right | 6' 3" | 225 lbs | $480,000 |
| Sánchez, Jesús | C | Greenville 84s | 18 | 04/13/2013 | San Pedro Sacatepéquez | GUA | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, Juan | SP | New Amsterdam Dutchmen | 18 | 10/01/2013 | Moca | DOM | Right | Right | 5' 8" | 150 lbs | - |
| Sánchez, Mariano | RF | Grafton Middies | 29 | 04/14/2002 | Esperalvillo | DOM | Right | Right | 5' 11" | 210 lbs | $280,000 |
| Sánchez, Miguel | SP | Wizarding Express | 17 | 10/26/2014 | Garza García | MEX | Left | Left | 6' 2" | 180 lbs | - |
| Sánchez, Rafael | RF | Toledo Stingers | 28 | 02/10/2003 | San Cristóbal | DOM | Left | Left | 6' 3" | 225 lbs | $8,800,000 |
| Sánchez, Roberto | C | Echo Park Lakers | 17 | 12/05/2014 | Santiago | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sanders, Cory | SP | Toledo Stingers | 34 | 11/08/1997 | Estero | USA | Right | Right | 6' 5" | 240 lbs | $17,720,000 |
| Santiago, Rafael | SP | Echo Park Lakers | 18 | 10/27/2013 | Yara | CUB | Right | Right | 5' 10" | 170 lbs | - |
| Santos, Manuel | C | Rocky Mountain Nuggets | 17 | 03/17/2014 | Guadalupe | CRC | Right | Right | 6' 4" | 210 lbs | - |
| Santos, Pedro | 2B | Grafton Middies | 32 | 07/27/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 225 lbs | $21,200,000 |
| Sarmiento, Marcos | RP | Grafton Middies | 23 | 09/12/2008 | Port-au-Prince | HAI | Right | Right | 6' 3" | 205 lbs | $280,000 |
| Sasaki, Takiji | RP | Free Agent | 29 | 03/26/2002 | Kushiro City | JPN | Right | Right | 6' 2" | 205 lbs | - |
| Satyavrat, Manoo | CF | Philadelphia 1776 BC | 26 | 08/15/2005 | Pehlad Pur Bangar | IND | Left | Left | 6' 1" | 195 lbs | $12,718,750 |
| Scheving, Magnus | RP | Rocky Mountain Nuggets | 25 | 08/06/2006 | Unknown | ISL | Left | Left | 6' 2" | 190 lbs | $280,000 |
| Schnatter, John | C | Philadelphia 1776 BC | 30 | 04/19/2001 | Pomona | USA | Right | Right | 6' 0" | 225 lbs | $550,000 |
| Schultz, Jon | RP | Free Agent | 30 | 12/25/2001 | Brownsville | USA | Right | Right | 6' 5" | 225 lbs | - |
| Schultz, Owen | SP | Seattle Aviators | 19 | 12/25/2012 | Cole Bay | SIM | Right | Right | 6' 3" | 185 lbs | - |
| Seacat, IV | RF | Richardson City Thundercats | 28 | 12/19/2003 | Southlake | USA | Right | Right | 6' 1" | 205 lbs | $850,000 |
| Sexton, Jeb | SS | Chicago Gold Sox | 25 | 03/29/2006 | Joal-Fadiouth | SEN | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sheppard, Matt | 3B | Rocky Mountain Nuggets | 35 | 11/14/1996 | Vermillion | USA | Right | Right | 5' 9" | 205 lbs | $1,100,000 |
| Shu, Pi-ao | SP | Thunder Bay Northern Lions BC | 18 | 08/25/2013 | Tainan | TPE | Right | Right | 6' 7" | 210 lbs | - |
| Silva, Dylan | SP | Grafton Middies | 29 | 10/17/2002 | Minneapolis | USA | Switch | Right | 6' 1" | 210 lbs | $1,400,000 |
| Silva, Javier | CF | Rocky Mountain Nuggets | 18 | 07/13/2013 | Estelí | NCA | Switch | Right | 6' 0" | 170 lbs | - |
| Silva, Rob | SP | Toledo Stingers | 26 | 02/28/2005 | Phoenix | USA | Switch | Right | 6' 1" | 210 lbs | $280,000 |
| Sison, Jim | SP | Rocky Mountain Nuggets | 24 | 05/15/2007 | Manton | USA | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Slade, Wayne | SP | Athletic Club KC | 23 | 01/20/2008 | Markham | CAN | Right | Right | 6' 2" | 195 lbs | $280,000 |
| Soisalo, Pellervo | SP | Ft. Worth Cattlemen | 18 | 10/16/2013 | Komadi | HUN | Left | Left | 6' 3" | 185 lbs | - |
| Solís, Jesús | SP | Wizarding Express | 17 | 07/29/2014 | Valencia | VEN | Right | Right | 6' 5" | 190 lbs | - |
| Solís, Pedro | C | Athletic Club KC | 27 | 10/06/2004 | Santo Domingo | DOM | Right | Right | 6' 1" | 220 lbs | $280,000 |
| Solíz, Tony | RP | Philadelphia 1776 BC | 27 | 01/12/2004 | Papantla | MEX | Right | Right | 6' 2" | 210 lbs | $2,600,000 |
| Song, Eun-bum | CF | D.C. Divided | 19 | 02/06/2012 | Pyongyang | PRK | Right | Left | 6' 1" | 170 lbs | - |
| Sosa, Ernesto | C | Wizarding Express | 16 | 08/29/2015 | Santo Domingo | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Sosa, Fernando | SP | Grafton Middies | 17 | 07/20/2014 | Santo Domingo | DOM | Right | Left | 6' 0" | 170 lbs | - |
| Soto, Bartolo | RF | Grafton Middies | 22 | 09/07/2009 | Puerto Plata | DOM | Left | Left | 6' 2" | 195 lbs | $280,000 |
| Sousa, Rodrigo | SS | Athletic Club KC | 18 | 06/18/2013 | Rosario | ARG | Right | Right | 6' 0" | 175 lbs | - |
| Spencer, J.J. | RP | New Amsterdam Dutchmen | 26 | 07/14/2005 | Tonawanda CDP | USA | Left | Right | 5' 10" | 200 lbs | $430,000 |
| Stanford, Ethan | 2B | Grafton Middies | 34 | 03/18/1997 | Battle Creek | USA | Right | Right | 6' 1" | 240 lbs | $420,000 |
| Stidston, Fergus | SS | Echo Park Lakers | 17 | 02/16/2014 | Oranjestad | ARU | Switch | Right | 6' 1" | 165 lbs | - |
| Sturges, Nigel | SS | New Amsterdam Dutchmen | 19 | 07/29/2012 | Avarua | COK | Right | Right | 6' 3" | 185 lbs | - |
| Summey, Kent | SS | Philadelphia 1776 BC | 28 | 07/12/2003 | Minneapolis | USA | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Sung, Jing-quo | RF | Brooklyn Dodgers | 19 | 10/24/2012 | Pingtung | TPE | Left | Left | 6' 3" | 185 lbs | - |
| Sung-Man, Sook | SP | Athletic Club KC | 26 | 06/11/2005 | Unknown | KOR | Right | Right | 6' 3" | 210 lbs | $280,000 |
| Swanson, Rusty | SP | New Amsterdam Dutchmen | 27 | 11/01/2004 | Elizabeth | USA | Right | Left | 6' 6" | 230 lbs | $5,100,000 |
