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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saikawa, Toshiro | RP | Kingston Township Legion | 34 | 06/29/1994 | Hiroshima | JPN | Left | Right | 5' 8" | 200 lbs | $8,500,000 |
| Saikawa, Yoshii | SS | New Amsterdam Dutchmen | 18 | 11/02/2010 | Hannan | JPN | Right | Right | 5' 10" | 170 lbs | - |
| Sakoda, Shigeko | RP | Free Agent | 23 | 04/12/2005 | Unknown | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Salaedo, Pancho | SS | Free Agent | 29 | 12/19/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 210 lbs | - |
| Salazar, Ramiro | CF | Montana Pandas | 34 | 09/10/1994 | Memphis | USA | Switch | Right | 6' 0" | 190 lbs | $16,640,000 |
| Salinas, José | SP | New Amsterdam Dutchmen | 16 | 08/07/2012 | Valencia | VEN | Right | Right | 6' 1" | 170 lbs | - |
| Samoyoa, Andrés | RP | Free Agent | 22 | 08/09/2006 | Valencia | VEN | Left | Left | 6' 0" | 180 lbs | - |
| Sánchez, António | C | Chicago Hawks | 16 | 11/20/2012 | Santo Domingo | DOM | Right | Right | 5' 11" | 190 lbs | - |
| Sánchez, Carlos | SP | Philadelphia 1776 BC | 27 | 06/04/2001 | Maracaibo | VEN | Left | Left | 6' 2" | 210 lbs | $9,000,000 |
| Sánchez, Félix | SS | Rocky Mountain Nuggets | 19 | 02/22/2009 | San Pedro Sula | HON | Right | Right | 6' 0" | 170 lbs | - |
| Sánchez, Francisco | LF | Capital District Red Knights | 32 | 07/09/1996 | Río Grande | PUR | Left | Left | 6' 0" | 200 lbs | $750,000 |
| Sánchez, Jesús | 2B | Capital District Red Knights | 19 | 11/09/2009 | La Concepción | PAN | Right | Right | 6' 0" | 175 lbs | - |
| Sánchez, Juan | 3B | Brooklyn Dodgers | 19 | 08/07/2009 | Higüey | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, Luis | SP | Las Vegas Flamingos | 18 | 06/03/2010 | Santo Domingo | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Sánchez, Raúl | SP | Brooklyn Dodgers | 20 | 10/20/2008 | Bajos de Haina | DOM | Right | Right | 5' 11" | 175 lbs | - |
| Sanders, Cory | SP | Philadelphia 1776 BC | 31 | 11/08/1997 | Estero | USA | Right | Right | 6' 5" | 240 lbs | $9,000,000 |
| Sanders, Israel | SS | Buckhead Bowties | 29 | 08/27/1999 | Dallas | USA | Right | Right | 6' 4" | 230 lbs | $280,000 |
| Santos, José | SS | Buckhead Bowties | 19 | 06/17/2009 | Carora | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sarrano, Elder | CF | Free Agent | 17 | 07/04/2011 | Guatire | VEN | Right | Right | 6' 4" | 195 lbs | - |
| Sassetti, Timoteo | SP | Houston 1837 BBC | 17 | 12/30/2011 | Caltanissetta | ITA | Right | Right | 5' 9" | 155 lbs | - |
| Satyavrat, Manoo | CF | Philadelphia 1776 BC | 23 | 08/15/2005 | Pehlad Pur Bangar | IND | Left | Left | 6' 1" | 185 lbs | $280,000 |
| Schellenberg, Janos | 1B | Greenville 84s | 18 | 10/19/2010 | Friedberg | GER | Switch | Right | 6' 2" | 210 lbs | - |
| Schnatter, John | C | Philadelphia 1776 BC | 27 | 04/19/2001 | Pomona | USA | Right | Right | 6' 0" | 225 lbs | $280,000 |
| Schuler, Omar | 2B | New Amsterdam Dutchmen | 26 | 09/09/2002 | Frankfurt | GER | Right | Right | 6' 3" | 205 lbs | $480,000 |
| Scott, Jim | 3B | Kingston Township Legion | 28 | 09/14/2000 | Alexandria | USA | Right | Right | 6' 0" | 205 lbs | $2,375,000 |
| Seixal, Quintiliano | RP | Greenville 84s | 27 | 07/17/2001 | Teresópolis | BRA | Right | Right | 6' 4" | 205 lbs | $1,500,000 |
| Serrado, Ernesto | SP | Capital District Red Knights | 17 | 01/01/2011 | Monte Grande | CRC | Right | Right | 6' 4" | 180 lbs | - |
| Serrano, Dani | C | Greenville 84s | 30 | 11/02/1998 | Encrucijada | CUB | Right | Right | 6' 3" | 230 lbs | $500,000 |
| Shaw, Roger | RP | Kingston Township Legion | 27 | 05/01/2001 | Holton | USA | Left | Left | 5' 10" | 195 lbs | $480,000 |
| Sicak, Matous | CF | Toledo Stingers | 17 | 05/14/2011 | Velka Bystrice | CZE | Right | Right | 6' 2" | 175 lbs | - |
| Siebert, Leon | RP | Montana Pandas | 25 | 12/29/2003 | Shackelford | USA | Right | Right | 6' 4" | 215 lbs | $280,000 |
| Silva, José | SP | Chicago Hawks | 18 | 12/14/2010 | Masaya | NCA | Right | Left | 5' 10" | 155 lbs | - |
| Silva, Rob | SP | Toledo Stingers | 23 | 02/28/2005 | Phoenix | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Simpson, Jeff | LF | Chicago Hawks | 22 | 08/24/2006 | Belton | USA | Left | Right | 6' 0" | 175 lbs | $280,000 |
| Sin, Seung-min | SS | Las Vegas Flamingos | 19 | 12/17/2009 | Pyongyang | PRK | Left | Right | 6' 1" | 175 lbs | - |
| Smith, Gareth | SS | Portland Evergreens | 17 | 11/01/2011 | Oranjestad | ARU | Right | Right | 6' 2" | 175 lbs | - |
| Smith, Mark | SP | Portland Evergreens | 18 | 12/15/2010 | San Ignacio | BLZ | Right | Right | 6' 2" | 180 lbs | - |
| Smith, Paul | 3B | Free Agent | 35 | 02/04/1993 | Wrightsboro | USA | Right | Right | 6' 2" | 230 lbs | - |
| Snel, Cor | RP | Philadelphia 1776 BC | 27 | 10/15/2001 | Tera Kora | ANT | Right | Right | 6' 2" | 215 lbs | $420,000 |
| Soliman, Boboy | C | Buckhead Bowties | 18 | 09/10/2010 | Manila | PHI | Right | Right | 6' 1" | 195 lbs | - |
| Son, Hung | SP | Las Vegas Flamingos | 19 | 09/06/2009 | My Tho | VIE | Left | Left | 6' 2" | 180 lbs | - |
| Song, Xiu-tou | SP | Greenville 84s | 16 | 10/13/2012 | Hsintien | TPE | Right | Right | 6' 5" | 195 lbs | - |
| Sosa, Jesús | C | Brooklyn Dodgers | 19 | 02/18/2009 | Juan Adrian | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Soto, Felipe | LF | Greenville 84s | 17 | 06/06/2011 | Buenos Aires | ARG | Left | Left | 6' 2" | 195 lbs | - |
| Soto, Júlio | SS | Brooklyn Dodgers | 17 | 09/19/2011 | El Factor | DOM | Switch | Right | 6' 1" | 170 lbs | - |
| Spencer, J.J. | SP | New Amsterdam Dutchmen | 23 | 07/14/2005 | Tonawanda CDP | USA | Left | Right | 5' 10" | 190 lbs | $280,000 |
| Stark, Ed | RP | Toledo Stingers | 29 | 09/14/1999 | Madera | USA | Right | Right | 6' 1" | 205 lbs | $550,000 |
| Stewart, Austin | SP | Chicago Hawks | 30 | 01/13/1998 | Queens | USA | Right | Right | 6' 0" | 195 lbs | $850,000 |
| Struck, Ty | 3B | Portland Evergreens | 26 | 07/08/2002 | Long Beach | USA | Right | Right | 6' 1" | 215 lbs | $280,000 |
| Stuy, Elwiin | 2B | Portland Evergreens | 17 | 01/05/2011 | Princess Quarter | SIM | Right | Right | 6' 3" | 190 lbs | - |
| Suárez, Galtero | C | Houston 1837 BBC | 22 | 04/02/2006 | Santo Domingo | DOM | Switch | Right | 6' 0" | 190 lbs | $280,000 |
| Suárez, Ricardo | SP | Houston 1837 BBC | 24 | 03/21/2004 | Duvergé | DOM | Right | Right | 6' 6" | 210 lbs | $280,000 |
| Suker, Bedrettin | 3B | Greenville 84s | 16 | 06/04/2012 | Singen | GER | Right | Right | 6' 0" | 175 lbs | - |
| Sullivan, Tommy | LF | Kingston Township Legion | 26 | 12/17/2002 | New Brunswick | USA | Left | Left | 5' 9" | 190 lbs | $280,000 |
| Sutinen, Arvi | CF | Toledo Stingers | 17 | 08/24/2011 | Budapest | HUN | Right | Right | 6' 4" | 200 lbs | - |
| Svendsen, Aksel | SP | Capital District Red Knights | 18 | 12/25/2010 | Sønder Omme | DEN | Right | Right | 6' 0" | 175 lbs | - |
| Swain, Bobby | SP | New Amsterdam Dutchmen | 29 | 12/28/1999 | Socastee | USA | Right | Right | 6' 0" | 190 lbs | $2,800,000 |
| Swanson, Rusty | SP | New Amsterdam Dutchmen | 24 | 11/01/2004 | Elizabeth | USA | Right | Left | 6' 6" | 215 lbs | $2,375,000 |
