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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Valentín | 3B | Richland Rails | 28 | 08/27/1999 | Chicago Heights | USA | Left | Right | 6' 0" | 205 lbs | - |
| Saldaña, Jorge | SS | Casper Ghosts | 27 | 06/03/2000 | Monte Plata | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Salimbeni, Luchino | SS | Atlantic City Sonics | 24 | 04/20/2003 | Araure | VEN | Switch | Right | 6' 4" | 200 lbs | - |
| Sánchez, León | SS | Free Agent | 24 | 04/16/2003 | San Miguelito | PAN | Right | Right | 6' 1" | 180 lbs | - |
| Sánchez, Rubén | RP | Ft. Polk South Thunder Hawks | 31 | 10/23/1996 | San Juan | PUR | Right | Right | 6' 4" | 190 lbs | - |
| Sanders, Jasper | SP | Long Island Seawolves | 23 | 01/21/2004 | South Hill | USA | Left | Left | 6' 2" | 205 lbs | - |
| Sanders, Josh | CF | Long Island Seawolves | 24 | 09/27/2003 | Richmond | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Sentell, Todd | CF | Casper Ghosts | 21 | 05/25/2006 | Jacksonville | USA | Right | Right | 5' 11" | 175 lbs | - |
| Shankland, Gregory | 3B | Ft. Polk South Thunder Hawks | 24 | 10/04/2003 | Mililani Town | USA | Right | Right | 6' 1" | 220 lbs | - |
| Shanks, Tristan | 2B | Ottawa Nationals | 24 | 08/10/2003 | Jamestown | USA | Switch | Right | 6' 2" | 205 lbs | - |
| Shearman, Henrique | C | Free Agent | 26 | 11/27/2001 | Valparaiso de Goias | BRA | Right | Right | 5' 11" | 200 lbs | - |
| Shelton, Walt | CF | Ft. Polk South Thunder Hawks | 27 | 04/01/2000 | Herndon | USA | Right | Right | 6' 2" | 215 lbs | - |
| Sherratt, David | RP | Atlantic City Sonics | 25 | 02/03/2002 | Reading | ENG | Left | Left | 6' 2" | 195 lbs | - |
| Shoffner, Mark | SS | Long Island Seawolves | 22 | 10/09/2005 | Winchester | USA | Right | Right | 6' 0" | 185 lbs | - |
| Simmons, Earl | SP | Casper Ghosts | 26 | 02/12/2001 | Mt. Vernon | USA | Right | Right | 6' 0" | 190 lbs | - |
| Simon, Maxwell | SP | Richland Rails | 27 | 09/24/2000 | Imperial Beach | USA | Right | Right | 5' 10" | 185 lbs | - |
| Simpson, Jeff | LF | Virginia Beach Deuces | 21 | 08/24/2006 | Belton | USA | Left | Right | 6' 0" | 175 lbs | - |
| Smith, Rob | RP | Atlantic City Sonics | 27 | 04/15/2000 | Kendall West | USA | Left | Left | 6' 1" | 195 lbs | - |
| Snyder, Anthony | RP | Casper Ghosts | 34 | 04/20/1993 | Brooklyn | USA | Right | Right | 6' 0" | 200 lbs | - |
| Solís, Jaime | 2B | San Bernardino Grasshoppers | 23 | 01/08/2004 | Ocumare del Tuy | VEN | Right | Right | 6' 0" | 175 lbs | - |
| Solís, Ramón | SP | Ft. Polk South Thunder Hawks | 22 | 01/14/2005 | Rubio | VEN | Left | Right | 6' 2" | 185 lbs | - |
| Sosa, José | 2B | Free Agent | 28 | 03/17/1999 | La Mata | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Spencer, Jeremiah | SS | Free Agent | 31 | 02/18/1996 | Monroe | USA | Left | Right | 6' 3" | 230 lbs | - |
| Spiers, Reg | SS | Virginia Beach Deuces | 21 | 07/02/2006 | Unknown | AUS | Right | Right | 6' 2" | 180 lbs | - |
| Stephens, Oscar | SS | Virginia Beach Deuces | 25 | 11/11/2002 | The Woodlands | USA | Right | Right | 6' 1" | 200 lbs | - |
| Strickland, Philip | RF | Myrtle Beach Mermen | 26 | 04/05/2001 | Queens | USA | Left | Left | 5' 10" | 210 lbs | $280,000 |
| Sullivan, Kendrick | 2B | Virginia Beach Deuces | 24 | 10/21/2003 | Blackwell | USA | Left | Right | 6' 0" | 200 lbs | - |
| Surambe, Restin P. | CF | Glendale Herons | 23 | 12/27/2004 | Cincinnati | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sweet, Del | RP | Free Agent | 25 | 02/20/2002 | Mont Belvieu | USA | Right | Right | 5' 10" | 190 lbs | - |
