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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabastro, Lorenzo | SS | Chicago Hawks | 26 | 01/13/2000 | Fusagasuga | COL | Right | Right | 6' 1" | 205 lbs | $280,000 |
| Sáenz, Emílio | RF | Las Vegas Flamingos | 34 | 11/24/1992 | Baltimore | USA | Left | Left | 5' 10" | 205 lbs | $756,000 |
| Sagástegui, Carlos | SP | Wizarding Express | 19 | 10/07/2007 | Rincón | DOM | Left | Left | 6' 2" | 175 lbs | - |
| Saikawa, Toshiro | CL | Kingston Township Legion | 32 | 06/29/1994 | Hiroshima | JPN | Left | Right | 5' 8" | 190 lbs | $6,500,000 |
| Saikawa, Yoshihito | 3B | Greenville 84s | 35 | 10/16/1991 | Kannabe | JPN | Right | Right | 6' 2" | 230 lbs | $1,610,000 |
| Sakata, Masaharu | SP | Rocky Mountain Nuggets | 18 | 03/22/2008 | Musashimurayama | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Salaedo, Pancho | 2B | Montana Pandas | 27 | 12/19/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 205 lbs | $448,000 |
| Salazar, Martín | SP | Austin Rangers | 20 | 05/29/2006 | Santiago | DOM | Right | Left | 6' 1" | 170 lbs | - |
| Salazar, Ramiro | CF | Montana Pandas | 32 | 09/10/1994 | Memphis | USA | Switch | Right | 6' 0" | 190 lbs | $15,610,000 |
| Salazar, Roberto | RF | Las Vegas Flamingos | 27 | 08/01/1999 | Pizarrete | DOM | Left | Left | 6' 2" | 200 lbs | $11,840,000 |
| Samson, Addie | SP | Brooklyn Dodgers | 26 | 03/01/2000 | Westerveld | NED | Left | Left | 6' 1" | 195 lbs | $1,280,000 |
| Samurakami, Ieyoshi | 1B | Montana Pandas | 16 | 07/27/2010 | Nara | JPN | Left | Left | 6' 4" | 220 lbs | - |
| Sánchez, Carlos | SP | Philadelphia 1776 BC | 25 | 06/04/2001 | Maracaibo | VEN | Left | Left | 6' 2" | 200 lbs | $9,000,000 |
| Sánchez, Félix | SS | Rocky Mountain Nuggets | 17 | 02/22/2009 | San Pedro Sula | HON | Right | Right | 6' 0" | 165 lbs | - |
| Sánchez, Francisco | LF | Capital District Red Knights | 30 | 07/09/1996 | Río Grande | PUR | Left | Left | 6' 0" | 205 lbs | $644,000 |
| Sánchez, Javier | 1B | Rocky Mountain Nuggets | 22 | 03/01/2004 | Villa Vazquez | DOM | Left | Left | 6' 4" | 225 lbs | $5,000,000 |
| Sánchez, Jesús | 2B | Capital District Red Knights | 17 | 11/09/2009 | La Concepción | PAN | Right | Right | 6' 0" | 175 lbs | - |
| Sánchez, Juan | 3B | Brooklyn Dodgers | 17 | 08/07/2009 | Higüey | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Sánchez, Juan | C | Portland Evergreens | 36 | 11/19/1990 | Valencia | VEN | Switch | Right | 6' 3" | 250 lbs | $756,000 |
| Sánchez, Luis | SP | Las Vegas Flamingos | 16 | 06/03/2010 | Santo Domingo | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Sánchez, Luis | SP | Kingston Township Legion | 19 | 07/19/2007 | Ciudad Guayana | VEN | Right | Right | 5' 10" | 160 lbs | - |
| Sánchez, Raúl | SP | Brooklyn Dodgers | 18 | 10/20/2008 | Bajos de Haina | DOM | Right | Right | 5' 11" | 170 lbs | - |
| Sanders, Cory | SP | Philadelphia 1776 BC | 29 | 11/08/1997 | Estero | USA | Right | Right | 6' 5" | 240 lbs | $3,206,000 |
| Sandoval, José | RP | Montana Pandas | 27 | 04/05/1999 | Santo Domingo | DOM | Left | Left | 6' 8" | 220 lbs | $280,000 |
| Sandoval, Ricardo | SS | D.C. Divided | 20 | 09/03/2006 | Maracaibo | VEN | Right | Right | 6' 1" | 175 lbs | - |
| Sandry, Shaun | SP | Las Vegas Flamingos | 18 | 07/31/2008 | Orange Walk | BLZ | Right | Right | 6' 7" | 200 lbs | - |
| Santos, Javier | 2B | Free Agent | 26 | 08/30/2000 | Turmero | VEN | Right | Right | 6' 1" | 180 lbs | - |
| Sargent, Bob | 1B | Kingston Township Legion | 29 | 03/12/1997 | West Belmar | USA | Right | Right | 6' 1" | 235 lbs | $280,000 |
| Sasaki, Ryobe | C | Philadelphia 1776 BC | 19 | 10/29/2007 | Nagoya | JPN | Right | Right | 6' 4" | 205 lbs | - |
| Sato, Suezo | RP | Free Agent | 37 | 04/09/1989 | Tajimi | JPN | Right | Right | 6' 0" | 220 lbs | - |
| Schlosser, Randy | LF | Brooklyn Dodgers | 25 | 10/02/2001 | Fox Farm-College | USA | Left | Right | 5' 10" | 185 lbs | $280,000 |
| Schuilenberg, Kasper | C | Capital District Red Knights | 18 | 09/14/2008 | Cole Bay | SIM | Right | Right | 6' 0" | 185 lbs | - |
| Schuler, Omar | 2B | New Amsterdam Republics | 24 | 09/09/2002 | Frankfurt | GER | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Scott, Jim | 3B | Kingston Township Legion | 26 | 09/14/2000 | Alexandria | USA | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Sears, Ray | 3B | Montana Pandas | 35 | 04/08/1991 | Pharr | USA | Left | Right | 5' 11" | 200 lbs | $23,230,000 |
| See-to, Xi-ku | LF | Las Vegas Flamingos | 17 | 11/01/2009 | Honggang | CHN | Right | Right | 6' 5" | 200 lbs | - |
| Seixal, Quintiliano | SP | Greenville 84s | 25 | 07/17/2001 | Teresópolis | BRA | Right | Right | 6' 4" | 205 lbs | $280,000 |
| Seng, Khemera | SP | Seattle Aviators | 19 | 08/13/2007 | Siem Reab | CAM | Left | Left | 6' 2" | 185 lbs | - |
| Serrano, Dani | C | Greenville 84s | 28 | 11/02/1998 | Encrucijada | CUB | Right | Right | 6' 3" | 230 lbs | $450,000 |
| Shannon, Wes | CF | Rocky Mountain Nuggets | 25 | 07/03/2001 | Aurora | USA | Right | Right | 6' 2" | 210 lbs | $1,458,000 |
| Shaw, Roger | SP | Kingston Township Legion | 25 | 05/01/2001 | Holton | USA | Left | Left | 5' 10" | 185 lbs | $280,000 |
| Shibata, Arinori | RP | Greenville 84s | 33 | 11/05/1993 | Oyama | JPN | Right | Right | 6' 0" | 200 lbs | $1,800,000 |
| Sierra, Albert | SP | Brooklyn Dodgers | 17 | 11/05/2009 | Fantino | DOM | Right | Right | 6' 1" | 170 lbs | - |
| Silva, Francisco | SP | Wizarding Express | 19 | 09/06/2007 | San José | CRC | Right | Right | 6' 6" | 195 lbs | - |
| Simonse, Bartho | 3B | Kingston Township Legion | 18 | 03/28/2008 | Rijnsburg | NED | Right | Right | 6' 2" | 195 lbs | - |
| Sin, Seung-min | SS | Las Vegas Flamingos | 17 | 12/17/2009 | Pyongyang | PRK | Left | Right | 6' 1" | 175 lbs | - |
| Smith, Joe | C | Free Agent | 29 | 07/25/1997 | New York | USA | Right | Right | 5' 11" | 200 lbs | - |
| Smith, Paul | 3B | Rocky Mountain Nuggets | 33 | 02/04/1993 | Wrightsboro | USA | Right | Right | 6' 2" | 220 lbs | $588,000 |
| Snel, Cor | RP | Philadelphia 1776 BC | 25 | 10/15/2001 | Tera Kora | ANT | Right | Right | 6' 2" | 210 lbs | $280,000 |
| So, Seung-hyeon | SP | Montana Pandas | 32 | 10/13/1994 | Ulsan | KOR | Left | Left | 6' 3" | 225 lbs | $19,500,000 |
| Sokolov, Bogdon | SP | Wizarding Express | 18 | 05/20/2008 | Leningradskaya | RUS | Right | Right | 6' 4" | 185 lbs | - |
| Son, Hung | SP | Las Vegas Flamingos | 17 | 09/06/2009 | My Tho | VIE | Left | Left | 6' 2" | 180 lbs | - |
| Sosa, Jesús | C | Brooklyn Dodgers | 17 | 02/18/2009 | Juan Adrian | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Spargo, Mick | 1B | Las Vegas Flamingos | 18 | 09/16/2008 | Ballarat | AUS | Right | Right | 6' 4" | 200 lbs | - |
| Spee, Sven | SS | Thunder Bay Northern Lions BC | 22 | 10/23/2004 | Utrecht | NED | Switch | Right | 6' 0" | 185 lbs | - |
| Spicer, Simon | SP | Wizarding Express | 19 | 09/21/2007 | Hastings | NZL | Left | Right | 6' 7" | 205 lbs | - |
| Stafford, Josh | 3B | Brooklyn Dodgers | 27 | 02/09/1999 | Splendora | USA | Right | Right | 6' 1" | 190 lbs | $280,000 |
| Steel, Isaac | SP | Capital District Red Knights | 19 | 06/22/2007 | Freeport | BAH | Right | Right | 5' 11" | 165 lbs | - |
| Stroo, Nees | SP | Austin Rangers | 18 | 09/23/2008 | Oranjestad | ARU | Left | Left | 6' 3" | 190 lbs | - |
| Suárez, Alfredo | CF | New Amsterdam Republics | 24 | 05/27/2002 | Managua | NCA | Right | Right | 6' 2" | 180 lbs | $280,000 |
| Suhendro, Jefferson | SP | Thunder Bay Northern Lions BC | 17 | 05/18/2009 | Sampang | IDN | Right | Right | 5' 11" | 165 lbs | - |
| Sullivan, Woody | RP | Free Agent | 29 | 09/02/1997 | Plymouth Township | USA | Left | Left | 6' 1" | 210 lbs | - |
| Swain, Bobby | SP | New Amsterdam Republics | 27 | 12/28/1999 | Socastee | USA | Right | Right | 6' 0" | 190 lbs | $3,500,000 |
| Swanson, Rusty | SP | New Amsterdam Republics | 22 | 11/01/2004 | Elizabeth | USA | Right | Left | 6' 6" | 205 lbs | $280,000 |
| Sykes, Richard | SP | Montana Pandas | 34 | 11/15/1992 | Milwaukee | USA | Right | Right | 6' 3" | 225 lbs | $850,000 |
| Sylvester, Terry | LF | Las Vegas Flamingos | 33 | 10/01/1993 | Montgomery Township | USA | Right | Right | 6' 0" | 210 lbs | $750,000 |
