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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Luis | 1B | Virginia Beach Deuces | 29 | 02/26/1994 | Tulsa | USA | Right | Right | 6' 0" | 220 lbs | - |
| Sagebrecht, Jurgen | SP | Lancaster Farmers | 21 | 08/03/2002 | New Milford | USA | Right | Right | 6' 7" | 225 lbs | - |
| Salinas, Juan | CF | Long Island Seawolves | 24 | 09/11/1999 | San Antonio Buenavista | MEX | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Samuels, Kevin | SP | Phoenix Hotspur Youth | 24 | 04/12/1999 | Wilkes-Barre | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sánchez, Juan | SP | Long Island Seawolves | 22 | 09/09/2001 | Cumana | VEN | Right | Right | 5' 11" | 175 lbs | - |
| Sánchez, Manuel | C | Marquette Miners | 23 | 06/10/2000 | La Romana | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Sánchez, Orlando | RP | Lancaster Farmers | 25 | 08/19/1998 | Santo Domingo | DOM | Left | Left | 6' 2" | 200 lbs | - |
| Sánchez, Ricardo | SP | Phoenix Hotspur Youth | 20 | 01/15/2003 | San Joaquín | VEN | Left | Left | 6' 2" | 190 lbs | - |
| Sánchez, Roberto | 1B | Chesapeake Continentals | 20 | 11/17/2003 | San José de Ocoa | DOM | Left | Left | 6' 3" | 200 lbs | - |
| Sanders, Bryan | SS | Chesapeake Continentals | 23 | 09/19/2000 | Ft. Wayne | USA | Right | Right | 5' 11" | 180 lbs | - |
| Sanford, Sean | RP | Yakima Hops | 24 | 11/03/1999 | Apple Valley | USA | Right | Right | 5' 9" | 180 lbs | - |
| Schlosser, Randy | LF | Richland Rails | 22 | 10/02/2001 | Fox Farm-College | USA | Left | Right | 5' 10" | 175 lbs | - |
| Shannon, Rich | SP | Long Island Seawolves | 24 | 01/20/1999 | East Peoria | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sharp, Ed | C | Phoenix Hotspur Youth | 24 | 09/23/1999 | Sioux Falls | USA | Right | Right | 5' 10" | 200 lbs | $280,000 |
| Shaw, Patrick | C | Phoenix Hotspur Youth | 25 | 01/08/1998 | Hammond | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sherman, Thomas | LF | Chesapeake Continentals | 23 | 02/02/2000 | Candia | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sherman, Will | 1B | Free Agent | 31 | 03/17/1992 | Lakewood | USA | Left | Left | 5' 10" | 210 lbs | - |
| Silverstro, Jorge | RP | Marquette Miners | 24 | 04/17/1999 | Sabanitas | PAN | Right | Right | 6' 2" | 200 lbs | - |
| Singer, Eddie | RP | Chesapeake Continentals | 24 | 03/21/1999 | Essex Fells | USA | Right | Right | 5' 9" | 180 lbs | - |
| Smith, Noah | 2B | Irving Blue Sox | 23 | 09/12/2000 | Bedford | USA | Right | Right | 5' 11" | 185 lbs | - |
| Stoltzfus, Chris | LF | Richland Rails | 26 | 08/06/1997 | Nashville | USA | Left | Left | 6' 0" | 200 lbs | - |
| Strauss, Billy | CF | Phoenix Hotspur Youth | 26 | 10/02/1997 | Gary | USA | Right | Right | 6' 3" | 210 lbs | $280,000 |
| Swanson, Martin | RP | Chesapeake Continentals | 22 | 01/22/2001 | Watertown | USA | Right | Right | 6' 2" | 180 lbs | - |
