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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakai, Naohiro | SS | Athletic Club KC U-21 | 21 | 11/08/2001 | Matsumoto | JPN | Left | Right | 6' 1" | 175 lbs | - |
| Salazar, Héctor | RP | Gwinnett County Black Cats | 20 | 12/08/2002 | Guatire | VEN | Right | Right | 6' 3" | 190 lbs | - |
| Saldaña, Jorge | SS | Mancelona Torch | 22 | 06/03/2000 | Monte Plata | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sánchez, Alberto | RP | Free Agent | 26 | 03/25/1996 | Queens | USA | Switch | Left | 6' 3" | 215 lbs | - |
| Sánchez, Alfredo | CL | Galesburg Guzzlers | 19 | 10/01/2003 | Juan de Acosta | COL | Left | Left | 6' 4" | 190 lbs | - |
| Sánchez, Enrico | SS | Phoenix Hotspur U-21 | 17 | 02/10/2005 | Villa Altagracia | DOM | Right | Right | 6' 4" | 190 lbs | - |
| Sánchez, Jorge | RP | Yellowknife Dragonblood | 21 | 04/05/2001 | Xico | MEX | Left | Left | 6' 0" | 165 lbs | - |
| Sánchez, José | RP | South Beach Blaze | 19 | 10/09/2003 | David | PAN | Left | Left | 6' 3" | 180 lbs | - |
| Sánchez, José | C | Phoenix Hotspur U-21 | 23 | 11/19/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 215 lbs | - |
| Sánchez, Manuel | SP | Hammond Herons | 23 | 11/20/1999 | San Juan | PUR | Switch | Right | 6' 2" | 205 lbs | - |
| Sánchez, Manuel | SP | Galesburg Guzzlers | 20 | 08/22/2002 | San Juan de la Maguana | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Sánchez, Orlando | 1B | Gwinnett County Black Cats | 23 | 09/04/1999 | Monte Cristi | DOM | Right | Left | 6' 2" | 215 lbs | - |
| Sánchez, Rafael | RF | Phoenix Hotspur U-21 | 19 | 02/10/2003 | San Cristóbal | DOM | Left | Left | 6' 3" | 195 lbs | - |
| Sánchez, Ricardo | SP | Phoenix Hotspur U-21 | 19 | 01/15/2003 | San Joaquín | VEN | Left | Left | 6' 2" | 185 lbs | - |
| Sandoval, Cristián | RP | Hammond Herons | 21 | 01/09/2001 | Alcalde Díaz | PAN | Right | Right | 6' 3" | 175 lbs | - |
| Schlosser, Randy | CF | Idaho Falls Chukars | 21 | 10/02/2001 | Fox Farm-College | USA | Left | Right | 5' 10" | 170 lbs | - |
| Schroeder, Dave | 3B | Yellowknife Dragonblood | 22 | 08/30/2000 | Roanoke | USA | Right | Right | 6' 1" | 195 lbs | - |
| Schuler, Omar | SS | South Beach Blaze | 20 | 09/09/2002 | Frankfurt | GER | Right | Right | 6' 3" | 190 lbs | - |
| Shelton, Ken | RP | South Beach Blaze | 22 | 07/28/2000 | Norfolk | USA | Right | Right | 6' 8" | 220 lbs | - |
| Sherman, Thomas | C | Galesburg Guzzlers | 22 | 02/02/2000 | Candia | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Silva, Dylan | SP | Phoenix Hotspur U-21 | 20 | 10/17/2002 | Minneapolis | USA | Switch | Right | 6' 1" | 185 lbs | - |
| Simpson, John | RP | Athletic Club KC U-21 | 23 | 12/25/1999 | Woodburn | USA | Right | Right | 6' 5" | 210 lbs | - |
| Solís, Víctor | RP | Yellowknife Dragonblood | 19 | 06/09/2003 | Ocaña | COL | Right | Right | 5' 10" | 160 lbs | - |
| Soto, Brian | CF | Hammond Herons | 22 | 02/02/2000 | College Park | USA | Right | Right | 6' 0" | 190 lbs | - |
| Spivey, Paul | RP | Free Agent | 22 | 01/01/2000 | Cincinnati | USA | Left | Right | 6' 4" | 200 lbs | - |
| Stephens, Ted | 2B | Idaho Falls Chukars | 21 | 03/19/2001 | Augusta | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sugahara, Shotaro | SP | Idaho Falls Chukars | 18 | 05/25/2004 | Nishinomiya | JPN | Right | Right | 5' 11" | 165 lbs | - |
