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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sam, Janghyun | 2B | Lancaster Farmers | 20 | 12/31/2001 | Suncheon | KOR | Switch | Right | 6' 1" | 185 lbs | - |
| Samuels, Patrick | 1B | Ottawa Nationals | 26 | 09/18/1995 | Kendale Lakes | USA | Right | Right | 6' 2" | 230 lbs | - |
| Sánchez, Carlos | 2B | Yakima Hops | 21 | 11/07/2000 | Carolina | PUR | Switch | Right | 6' 0" | 185 lbs | - |
| Sánchez, David | SS | Nortonville Cherokees | 22 | 11/30/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Sánchez, Eduardo | SS | Billings Polar Bears | 22 | 11/01/1999 | Jeffersonville | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sánchez, Enrique | LF | San Antonio BC | 19 | 10/29/2002 | Charallave | VEN | Left | Left | 6' 6" | 205 lbs | - |
| Sánchez, Jorge | RP | Atlantic City Sonics | 29 | 07/24/1992 | Santo Domingo | DOM | Right | Right | 6' 0" | 195 lbs | - |
| Sánchez, Manuel | RP | Atlantic City Sonics | 21 | 01/04/2000 | Catia La Mar | VEN | Left | Left | 6' 7" | 200 lbs | - |
| Sánchez, Orlando | RP | Lancaster Farmers | 23 | 08/19/1998 | Santo Domingo | DOM | Left | Left | 6' 2" | 190 lbs | - |
| Sánchez, Pedro | 3B | San Antonio BC | 30 | 01/21/1991 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 220 lbs | $280,000 |
| Sanford, Sean | RP | Yakima Hops | 22 | 11/03/1999 | Apple Valley | USA | Right | Right | 5' 9" | 170 lbs | - |
| Santos, Carlos | SS | Lancaster Farmers | 23 | 01/10/1998 | Los Angeles | USA | Right | Right | 6' 2" | 200 lbs | - |
| Schneider, Jeff | SP | Atlantic City Sonics | 21 | 06/03/2000 | Cincinnati | USA | Right | Left | 6' 3" | 200 lbs | - |
| Schroeder, Derek | 2B | Nortonville Cherokees | 31 | 06/12/1990 | Dallas | USA | Right | Right | 5' 11" | 195 lbs | - |
| Scott, Edward | RP | Tacoma Fur Traders | 24 | 01/16/1997 | River Edge | USA | Right | Right | 6' 3" | 215 lbs | - |
| Scott, Jamie | SP | San Antonio BC | 20 | 10/24/2001 | Elizabethton | USA | Right | Left | 6' 6" | 215 lbs | - |
| Serna, Raúl | SP | Ft. Polk South Thunder Hawks | 23 | 07/30/1998 | Santo Domingo | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Sherman, Dave | SS | Ottawa Nationals | 30 | 08/02/1991 | Tampa | USA | Right | Right | 6' 2" | 220 lbs | - |
| Shirley, John | SP | Battle Ground Aeros | 22 | 07/22/1999 | Appleton | USA | Right | Right | 6' 5" | 205 lbs | - |
| Si, Jen-djieh | RP | Battle Ground Aeros | 23 | 06/20/1998 | Taipei | TPE | Right | Right | 6' 0" | 195 lbs | - |
| Silva, Manuel | RP | Billings Polar Bears | 24 | 12/15/1997 | Moca | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Smith, Rob | RP | Atlantic City Sonics | 21 | 04/15/2000 | Kendall West | USA | Left | Left | 6' 1" | 185 lbs | - |
| Snel, Cor | CL | Billings Polar Bears | 20 | 10/15/2001 | Tera Kora | ANT | Right | Right | 6' 2" | 190 lbs | - |
| Snyder, David | 1B | Atlantic City Sonics | 24 | 05/02/1997 | Manasquan | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Soto, Jesús | C | Ottawa Nationals | 22 | 07/31/1999 | Santiago | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Soto, Joaquín | SP | Ft. Polk South Thunder Hawks | 25 | 04/13/1996 | Candler-McAfee | USA | Right | Left | 6' 0" | 200 lbs | - |
| Stanley, Tommy | CF | Ft. Polk South Thunder Hawks | 24 | 08/30/1997 | Stanton | USA | Right | Right | 5' 11" | 190 lbs | - |
| Stephenson, Edgar | 1B | Atlantic City Sonics | 24 | 01/04/1997 | Seattle | USA | Right | Right | 6' 2" | 220 lbs | - |
| Stewart, Ken | RP | San Antonio BC | 32 | 01/20/1989 | Santa Clarita | USA | Right | Right | 6' 3" | 215 lbs | $280,000 |
| Storey, Burton | 1B | Yakima Hops | 24 | 05/30/1997 | Vancouver | CAN | Switch | Right | 6' 7" | 250 lbs | - |
| Strickland, Tom | 3B | Belvedere Park Rawhides | 24 | 01/25/1997 | Oberlin | USA | Right | Right | 5' 11" | 200 lbs | - |
