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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, José | RF | Augusta Timber Hawks | 23 | 09/16/1995 | Tampa | USA | Switch | Left | 6' 3" | 220 lbs | - |
| Salazar, Mike | MR | Brinkley Belugas | 26 | 05/27/1992 | Irving | USA | Right | Right | 6' 1" | 200 lbs | $290,000 |
| Salinas, Claudio | MR | Free Agent | 33 | 12/25/1984 | La Vega | DOM | Right | Right | 6' 4" | 225 lbs | - |
| Sánchez, Juan | 3B | Warwick Hunchbacks | 34 | 12/02/1983 | Dajabón | DOM | Right | Right | 6' 2" | 220 lbs | $2,160,000 |
| Sánchez, Pedro | 3B | Free Agent | 27 | 01/21/1991 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 210 lbs | - |
| Sant' Ana, Ademar | MR | Hialeah Dodos | 26 | 06/22/1992 | Araucaria | BRA | Right | Right | 6' 2" | 205 lbs | $190,000 |
| Santos, Carlos | SS | Corpus Christi Twins | 20 | 01/10/1998 | Los Angeles | USA | Right | Right | 6' 2" | 185 lbs | - |
| Santos, Júlio | C | Corpus Christi Twins | 20 | 08/11/1998 | La Victoria | VEN | Right | Right | 6' 1" | 185 lbs | - |
| Sawallisch, Han | MR | Sylvania Maple Leaves | 29 | 11/02/1989 | Zweibrücken | GER | Left | Left | 6' 0" | 200 lbs | $1,800,000 |
| Schiffer, Lance | CF | Milton Bills | 21 | 03/20/1997 | Sterling | USA | Left | Left | 5' 11" | 175 lbs | $190,000 |
| Schroeder, Derek | 2B | Balboa Buccaneers | 28 | 06/12/1990 | Dallas | USA | Right | Right | 5' 11" | 195 lbs | $360,000 |
| Scott, Freddy | 1B | Warwick Hunchbacks | 28 | 02/24/1990 | Queens | USA | Right | Right | 6' 0" | 225 lbs | - |
| Shafer, Homer | MR | Augusta Timber Hawks | 21 | 06/25/1997 | Mesa | USA | Left | Left | 6' 2" | 185 lbs | - |
| Shankle, Jon | MR | Rappahannock Partisans | 25 | 07/20/1993 | Bonadelle Ranchos-Madera Ranchos | USA | Switch | Right | 6' 2" | 200 lbs | $650,000 |
| Shannon, Dennis | 2B | Brinkley Belugas | 34 | 11/17/1983 | Los Angeles | USA | Right | Right | 5' 10" | 200 lbs | - |
| Simons, Chris | 3B | Free Agent | 40 | 05/04/1978 | Los Angeles | USA | Right | Right | 6' 0" | 230 lbs | - |
| Sloan, Ernest | SP | Free Agent | 26 | 11/28/1991 | Claremont | USA | Right | Right | 6' 5" | 230 lbs | - |
| Smith, Michael | 3B | Corpus Christi Twins | 23 | 06/22/1995 | Minneapolis | USA | Left | Left | 6' 5" | 240 lbs | - |
| Stankovic, Branislav | MR | Brinkley Belugas | 24 | 03/11/1994 | Camp Pendleton South | USA | Right | Right | 6' 0" | 180 lbs | - |
| Stark, Tim | SP | Free Agent | 35 | 12/12/1982 | Lafayette | USA | Right | Right | 6' 6" | 235 lbs | - |
| Stevens, Randy | 1B | Free Agent | 29 | 04/26/1989 | Rochester Hills | USA | Left | Right | 6' 1" | 255 lbs | - |
| Strauss, Billy | CF | Augusta Timber Hawks | 21 | 10/02/1997 | Gary | USA | Right | Right | 6' 3" | 195 lbs | $190,000 |
| Strickland, Dean | 1B | Brinkley Belugas | 26 | 09/23/1992 | Ormond Beach | USA | Right | Left | 6' 5" | 260 lbs | - |
| Suárez, Juan | MR | Free Agent | 41 | 12/22/1976 | Paya | DOM | Left | Right | 5' 8" | 190 lbs | - |
| Sullivan, Don | RF | Corpus Christi Twins | 26 | 09/20/1992 | South Beloit | USA | Left | Left | 6' 1" | 200 lbs | - |
| Swain, Bill | MR | Balboa Buccaneers | 23 | 08/07/1995 | Dallas | USA | Right | Right | 5' 10" | 180 lbs | - |
