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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Salvador | SS | Wilmington Rebels | 23 | 05/20/1998 | Altamira | DOM | Right | Right | 6' 0" | 220 lbs | - |
| Salazar, José | LF | Springfield Simpsons | 22 | 09/11/1999 | Piedras Negras | MEX | Right | Left | 5' 8" | 180 lbs | - |
| Sammons, Bernie | MR | Reading Rainbows | 28 | 03/16/1993 | Montgomery | USA | Right | Right | 6' 2" | 220 lbs | - |
| Sánchez, José | 1B | Lima Oilers | 24 | 08/28/1997 | Rancho Cordova | USA | Right | Right | 6' 0" | 210 lbs | - |
| Sandoval, Júlio | MR | Newark Bulldogs | 26 | 10/19/1995 | Santo Domingo | DOM | Switch | Right | 6' 1" | 235 lbs | - |
| Santos, Esteban | SP | Mt Pleasant Bearcats | 25 | 02/03/1996 | Huntington Beach | USA | Left | Left | 5' 8" | 215 lbs | - |
| Sato, Hiroaki | SS | Free Agent | 25 | 10/16/1996 | Yoro | JPN | Right | Right | 6' 0" | 195 lbs | - |
| Sato, Ienobu | MR | Reading Rainbows | 21 | 03/29/2000 | Fukuoka | JPN | Left | Right | 6' 2" | 250 lbs | - |
| Schneider, Jeremy | SP | Butler White Sox | 25 | 03/06/1996 | Dedham | USA | Right | Right | 6' 2" | 220 lbs | - |
| Segura, Jesús | 3B | Reading Rainbows | 26 | 01/23/1995 | Ciudad Bolívar | VEN | Switch | Right | 6' 3" | 200 lbs | - |
| Seif, Hicham | SP | Springfield Simpsons | 26 | 09/24/1995 | Busia | KEN | Left | Left | 5' 9" | 230 lbs | - |
| Serrano, Roberto | LF | Reading Rainbows | 27 | 10/12/1994 | Santo Domingo | DOM | Switch | Right | 6' 6" | 165 lbs | - |
| Seymour, Nathan | SP | Reading Rainbows | 24 | 09/15/1997 | Homer Glen | USA | Right | Right | 6' 1" | 235 lbs | - |
| Sheppard, John | SP | Lima Oilers | 25 | 02/20/1996 | Senatobia | USA | Right | Right | 6' 3" | 210 lbs | - |
| Simon, Cole | MR | Lima Oilers | 26 | 02/09/1995 | Las Vegas | USA | Right | Right | 6' 0" | 250 lbs | - |
| Simon, Jimmy | RF | Reading Rainbows | 23 | 05/27/1998 | Los Angeles | USA | Right | Left | 6' 1" | 205 lbs | - |
| Simpson, Don | CF | Wilmington Rebels | 22 | 07/20/1999 | Augusta | USA | Right | Right | 5' 11" | 195 lbs | - |
| Small, Teddy | 3B | Wilmington Rebels | 25 | 12/17/1996 | Bloomingdale | USA | Right | Right | 5' 10" | 175 lbs | - |
| Smith, Bob | 1B | Wilmington Rebels | 24 | 10/01/1997 | Somerville | USA | Left | Left | 6' 4" | 205 lbs | - |
| Smith, Jason | SS | Newark Bulldogs | 22 | 08/04/1999 | Charlotte | USA | Right | Right | 6' 1" | 190 lbs | - |
| Smith, Taylor | 1B | Reading Rainbows | 22 | 08/20/1999 | Vinings | USA | Left | Left | 6' 3" | 200 lbs | - |
| So Jos, Etelson | LF | Reading Rainbows | 26 | 08/11/1995 | Anaco | VEN | Switch | Left | 6' 2" | 235 lbs | - |
| Solano, Víctor | CF | Springfield Simpsons | 25 | 04/29/1996 | Santiago | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Solíz, Mario | MR | Mt Pleasant Bearcats | 26 | 05/25/1995 | Juigalpa | NCA | Right | Left | 6' 0" | 215 lbs | - |
| Son, Young-kwang | MR | Buffalo LightSabres | 29 | 11/08/1992 | Anyang | KOR | Right | Right | 6' 1" | 190 lbs | - |
| Sotelo, Carlos | SS | Wilmington Rebels | 25 | 10/13/1996 | Durango | MEX | Right | Right | 5' 11" | 220 lbs | - |
| Soto, Juan | MR | Butler White Sox | 25 | 09/20/1996 | Higüey | DOM | Left | Left | 6' 1" | 215 lbs | - |
| St. John, Willie | SP | Mt Pleasant Bearcats | 22 | 04/29/1999 | Philadelphia | USA | Right | Right | 5' 10" | 235 lbs | - |
| Steele, Brad | MR | Reading Rainbows | 29 | 10/31/1992 | South Snyderville Basin | USA | Right | Right | 6' 0" | 210 lbs | - |
| Strong, Scotty | 2B | Buffalo LightSabres | 25 | 03/27/1996 | Attleboro | USA | Switch | Right | 5' 8" | 210 lbs | - |
| Stuckey, Pat | SP | Butler White Sox | 25 | 04/14/1996 | Toronto | CAN | Right | Right | 6' 3" | 250 lbs | - |
| Sugiyama, Nori | RF | Wilmington Rebels | 25 | 09/18/1996 | Gifu | JPN | Right | Right | 6' 2" | 200 lbs | - |
| Sugiyama, Tadakuni | C | Wilmington Rebels | 22 | 07/28/1999 | Koriyama | JPN | Right | Right | 6' 4" | 200 lbs | - |
