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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sáenz, Jorge | CF | Topeka Tornados | 29 | 10/28/1992 | Oranjestad | ARU | Right | Right | 6' 0" | 190 lbs | $1,400,000 |
| Sakurai, Rikiya | MR | Cape Cod Clams | 29 | 10/02/1992 | Fukuoka | JPN | Right | Right | 6' 5" | 250 lbs | - |
| Salazar, Luis | SP | Tuscaloosa Trout Slayers | 26 | 03/28/1995 | San Nicolas | CRC | Right | Right | 6' 0" | 200 lbs | - |
| Salinas, Miguel | C | Tuscaloosa Trout Slayers | 24 | 04/07/1997 | Havana | CUB | Right | Right | 6' 1" | 210 lbs | - |
| Sánchez, José | 3B | Waba Ducks | 24 | 12/12/1997 | Lincoln | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sánchez, Ramón | CF | Detroit X-Wings | 27 | 05/29/1994 | Pinar del Rio | CUB | Left | Left | 6' 1" | 170 lbs | - |
| Sasaki, Kanko | 2B | Free Agent | 35 | 12/29/1986 | Kamisato | JPN | Right | Right | 6' 1" | 195 lbs | - |
| Saunders, Mike | SP | Topeka Tornados | 31 | 03/14/1990 | Cherry Hill | USA | Switch | Right | 6' 1" | 230 lbs | - |
| Scott, Dan | 2B | Birmingham Barons | 29 | 11/09/1992 | Greenville | USA | Right | Right | 6' 0" | 200 lbs | - |
| Scott, Rob | 1B | Waba Ducks | 29 | 05/16/1992 | Houston | USA | Right | Right | 6' 2" | 210 lbs | - |
| Serrano, Juan | 3B | Detroit X-Wings | 26 | 03/17/1995 | Ecatepec | MEX | Right | Right | 6' 0" | 185 lbs | - |
| Shaw, Franklin | 2B | Cape Cod Clams | 26 | 05/14/1995 | Jacksonville | USA | Right | Right | 5' 11" | 185 lbs | - |
| Shiu, Ju-wei | 3B | Trenton Stars | 27 | 07/04/1994 | Keelung | TPE | Left | Right | 6' 2" | 210 lbs | - |
| Shiu, Ki-tong | MR | Trenton Stars | 27 | 04/28/1994 | Kaohsiung | TPE | Right | Right | 5' 11" | 220 lbs | - |
| Shook, Ron | CF | Wisconsin Timber Rattlers | 27 | 04/15/1994 | Toronto | CAN | Right | Right | 6' 0" | 200 lbs | - |
| Silva, Jesús | SP | Detroit X-Wings | 25 | 05/07/1996 | Havana | CUB | Right | Right | 6' 1" | 240 lbs | - |
| Silva, Ricardo | CF | Free Agent | 30 | 10/31/1991 | Homer | USA | Right | Right | 6' 2" | 235 lbs | - |
| Sims, Lee | RF | Portland Privateers | 28 | 02/08/1993 | Seattle | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sin, Cho-rin | 1B | Birmingham Barons | 30 | 01/12/1991 | Taegu | KOR | Right | Right | 6' 0" | 220 lbs | - |
| Small, Ed | 3B | Waba Ducks | 30 | 12/27/1991 | Memphis | USA | Right | Right | 6' 0" | 175 lbs | - |
| Somerville, Clint | CF | Free Agent | 30 | 01/07/1991 | Brisbane | AUS | Left | Right | 5' 11" | 200 lbs | - |
| Soto, Manuel | MR | Otsego Bulldogs | 29 | 10/19/1992 | Beverly | USA | Left | Left | 6' 5" | 215 lbs | - |
| Spears, Ted | MR | Free Agent | 36 | 03/21/1985 | Reno | USA | Right | Left | 6' 2" | 200 lbs | - |
| Stagg, Randy | SP | Free Agent | 34 | 07/03/1987 | Montreal | CAN | Left | Left | 6' 1" | 205 lbs | - |
| Stark, Millard | LF | Waba Ducks | 25 | 10/03/1996 | San Juan | PUR | Right | Right | 6' 4" | 220 lbs | - |
| Stewart, Dean | LF | Topeka Tornados | 32 | 01/21/1989 | Gulfport | USA | Left | Left | 6' 1" | 195 lbs | - |
| Stokes, Robert | 3B | Otsego Bulldogs | 34 | 08/17/1987 | Macomb | USA | Right | Right | 5' 8" | 210 lbs | - |
| Stone, Joseph | 3B | Wisconsin Timber Rattlers | 28 | 10/24/1993 | San Diego | USA | Right | Right | 6' 1" | 225 lbs | - |
| Stricker, John | MR | Otsego Bulldogs | 37 | 12/09/1984 | Memphis | USA | Left | Left | 5' 10" | 180 lbs | - |
| Sturdy, Mark | MR | Trenton Stars | 33 | 08/10/1988 | Lubbock | USA | Right | Right | 5' 10" | 220 lbs | - |
| Suárez, Jesús | SP | Birmingham Barons | 27 | 06/03/1994 | Beavercreek | USA | Right | Right | 6' 3" | 220 lbs | - |
| Sullivan, Oliver | RF | Portland Privateers | 31 | 11/07/1990 | Baileys Crossroads | USA | Left | Left | 6' 0" | 215 lbs | - |
| Suzuki, Hisashi | SS | Free Agent | 30 | 01/11/1991 | Kurashiki | JPN | Right | Right | 6' 0" | 210 lbs | - |
| Sykes, Otis | SP | Allentown Hillbillies | 25 | 09/17/1996 | Newport | USA | Left | Right | 5' 11" | 225 lbs | - |
