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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakurai, Rikiya | MR | Springfield Simpsons | 28 | 10/02/1992 | Fukuoka | JPN | Right | Right | 6' 5" | 250 lbs | - |
| Salgado, Nelson | C | Butler White Sox | 26 | 06/03/1994 | Ponce | PUR | Right | Right | 5' 8" | 195 lbs | - |
| Sammons, Bernie | MR | Reading Rainbows | 27 | 03/16/1993 | Montgomery | USA | Right | Right | 6' 2" | 215 lbs | - |
| Sánchez, Raúl | MR | Buffalo LightSabres | 24 | 08/20/1996 | Mastate | CRC | Left | Right | 6' 7" | 260 lbs | - |
| Sandoval, Júlio | MR | Newark Bulldogs | 25 | 10/19/1995 | Santo Domingo | DOM | Switch | Right | 6' 1" | 235 lbs | - |
| Santana, Gabriel | RF | Lima Oilers | 24 | 02/03/1996 | Encrucijada | CUB | Right | Right | 6' 4" | 215 lbs | - |
| Santos, Esteban | SP | Mt Pleasant Bearcats | 24 | 02/03/1996 | Huntington Beach | USA | Left | Left | 5' 8" | 215 lbs | - |
| Sato, Hiroaki | SS | Springfield Simpsons | 24 | 10/16/1996 | Yoro | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Segura, Jesús | 3B | Reading Rainbows | 25 | 01/23/1995 | Ciudad Bolívar | VEN | Switch | Right | 6' 3" | 200 lbs | - |
| Serrano, Roberto | LF | Reading Rainbows | 26 | 10/12/1994 | Santo Domingo | DOM | Switch | Right | 6' 6" | 165 lbs | - |
| Seymour, Nathan | SP | Reading Rainbows | 23 | 09/15/1997 | Homer Glen | USA | Right | Right | 6' 1" | 230 lbs | - |
| Sheppard, John | MR | Lima Oilers | 24 | 02/20/1996 | Senatobia | USA | Right | Right | 6' 3" | 210 lbs | - |
| Shiu, Ju-wei | 3B | Newark Bulldogs | 26 | 07/04/1994 | Keelung | TPE | Left | Right | 6' 2" | 205 lbs | - |
| Simmons, Mark | RF | Buffalo LightSabres | 24 | 10/19/1996 | Waterford | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Simon, Cole | MR | Lima Oilers | 25 | 02/09/1995 | Las Vegas | USA | Right | Right | 6' 0" | 245 lbs | - |
| Smith, Bob | SP | Butler White Sox | 27 | 12/01/1993 | North Las Vegas | USA | Right | Right | 5' 9" | 215 lbs | - |
| So Jos, Etelson | LF | Reading Rainbows | 25 | 08/11/1995 | Anaco | VEN | Switch | Left | 6' 2" | 230 lbs | - |
| Solano, Víctor | CF | Springfield Simpsons | 24 | 04/29/1996 | Santiago | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Solíz, Mario | MR | Mt Pleasant Bearcats | 25 | 05/25/1995 | Juigalpa | NCA | Right | Left | 6' 0" | 215 lbs | - |
| Son, Young-kwang | MR | Buffalo LightSabres | 28 | 11/08/1992 | Anyang | KOR | Right | Right | 6' 1" | 190 lbs | - |
| Sotelo, Carlos | SS | Wilmington Rebels | 24 | 10/13/1996 | Durango | MEX | Right | Right | 5' 11" | 215 lbs | - |
| Soto, Juan | SP | Butler White Sox | 24 | 09/20/1996 | Higüey | DOM | Left | Left | 6' 1" | 210 lbs | - |
| Steele, Brad | MR | Reading Rainbows | 28 | 10/31/1992 | South Snyderville Basin | USA | Right | Right | 6' 0" | 210 lbs | - |
| Stewart, Mark | MR | Buffalo LightSabres | 24 | 02/15/1996 | Philadelphia | USA | Left | Left | 6' 3" | 270 lbs | - |
| Sugiyama, Nori | RF | Wilmington Rebels | 24 | 09/18/1996 | Gifu | JPN | Right | Right | 6' 2" | 195 lbs | - |
| Sugiyama, Tadakuni | C | Wilmington Rebels | 21 | 07/28/1999 | Koriyama | JPN | Right | Right | 6' 4" | 200 lbs | - |
| Sykes, Otis | SP | Reading Rainbows | 24 | 09/17/1996 | Newport | USA | Left | Right | 5' 11" | 215 lbs | - |
