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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Manuel Villarreal | 215 | 2013-2022 | |
| 2 | Jorge Herrera | 199 | 2035-2052 | |
| 3 | Mariano Juderías# | 190 | 2042-2054 | |
| 4 | Wilbur Davis | 160 | 2026-2041 | |
| 5 | Karl Schultz | 102 | 2020-2032 | |
| 6 | Pedro Willis | 92 | 2013-2024 | |
| 7 | Rafael Martínez | 87 | 2043-2049 | |
| 8 | Jur Prokop | 85 | 2036-2048 | |
| 9 | Neil Lawson | 83 | 2016-2031 | |
| 10 | Pancho García | 78 | 2013-2025 | |
| 11 | Michael Malloy | 76 | 2027-2042 | |
| 12 | Daniel McCoy | 70 | 2032-2049 | |
| 12 | Yong-hong Ren# | 70 | 2043-2054 | |
| 12 | John Yossarian# | 70 | 2042-2054 | |
| 15 | Melvin Castro* | 65 | 2020-2035 | |
| 16 | Terrence Eler | 63 | 2018-2033 | |
| 17 | Stanley Belote | 61 | 2027-2037 | |
| 17 | Bernardo Elías | 61 | 2019-2032 | |
| 19 | Alfredo Martínez* | 56 | 2025-2041 | |
| 20 | Sasha Mamchenko# | 54 | 2050-2054 | |
| 20 | James Murray | 54 | 2013-2022 | |
| 22 | Francisco De La Cruz# | 53 | 2047-2054 | |
| 23 | Glyn Bolasky | 52 | 2029-2044 | |
| 23 | Rob Brooks | 52 | 2036-2046 | |
| 25 | Fernando Soto | 51 | 2038-2045 | |
| 26 | Armando Esparza | 50 | 2015-2027 | |
| 26 | Ishaan Swan# | 50 | 2047-2054 | |
| 26 | Craig Woods | 50 | 2037-2049 | |
| 29 | Chris Payling | 49 | 2028-2045 | |
| 30 | Jerry Harris | 46 | 2013-2019 | |
| 31 | Robert Adams | 45 | 2023-2029 | |
| 31 | Miguel Chávez | 45 | 2017-2021 | |
| 31 | Jasper Morrison | 45 | 2034-2043 | |
| 31 | Ramón Souza | 45 | 2018-2029 | |
| 31 | Marcos Zúñiga | 45 | 2014-2020 | |
| 36 | Dhataki Pummy# | 44 | 2046-2054 | |
| 36 | Jesús Vargas | 44 | 2029-2045 | |
| 38 | Arturo Hernández | 39 | 2013-2019 | |
| 39 | Yuk Cuan# | 38 | 2050-2054 | |
| 40 | Pedro Castillo | 37 | 2028-2032 | |
| 40 | Mike Gardner | 37 | 2018-2032 | |
| 40 | Tae-cho Han | 37 | 2031-2044 | |
| 43 | Rafael Arredondo | 36 | 2024-2032 | |
| 43 | Quincy Wass | 36 | 2042-2053 | |
| 43 | Arthur Witter# | 36 | 2046-2054 | |
| 46 | Tim Hargrove | 35 | 2016-2027 | |
| 46 | Eisse van Opdorp# | 35 | 2038-2054 | |
| 48 | Harry Cornelis | 34 | 2040-2046 | |
| 48 | Tom Smythe# | 34 | 2037-2054 | |
| 50 | Manuel Carmona | 32 | 2025-2042 | |
| 50 | Don Clark# | 32 | 2046-2052 | |
| 50 | Omar Luoa# | 32 | 2043-2051 | |
| 53 | Daniel Marley# | 31 | 2044-2054 | |
| 53 | Enrique Marroquín | 31 | 2020-2032 | |
| 55 | Esteban Sifuentes# | 30 | 2042-2050 | |
| 56 | Mark Curry# | 29 | 2048-2054 | |
| 56 | Wilfred McLaughlin* | 29 | 2018-2033 | |
| 56 | José Ruíz | 29 | 2027-2038 | |
| 56 | Mal Wadley | 29 | 2015-2028 | |
| 60 | León Castillo# | 28 | 2039-2050 | |
| 60 | Félix Pérez | 28 | 2013-2022 | |
| 60 | Guillermo Romero | 28 | 2013-2021 | |
| 63 | Julián Flores | 27 | 2049-2052 | |
| 63 | Gilberto Ocasio | 27 | 2036-2045 | |
| 63 | Pedro Vázquez | 27 | 2023-2036 | |
| 66 | Iiri Haapajarvi | 26 | 2039-2047 | |
| 66 | Jérôme Masson | 26 | 2029-2038 | |
| 66 | Ken Norman | 26 | 2015-2022 | |
| 66 | Michael Witt | 26 | 2037-2043 | |
| 70 | Brenton Hale# | 25 | 2051-2054 | |
| 70 | Joey Jones | 25 | 2019-2031 | |
| 70 | Rick Mayfield | 25 | 2028-2036 | |
| 70 | Jon Osterman | 25 | 2028-2044 | |
| 74 | Gustavo Gonzáles# | 23 | 2045-2054 | |
| 74 | Raúl Robles | 23 | 2017-2025 | |
| 74 | Yoichibei Sato | 23 | 2026-2033 | |
| 74 | Iván Vega | 23 | 2023-2037 | |
| 78 | David Breitling | 22 | 2028-2031 | |
| 78 | Brad Elmore | 22 | 2015-2025 | |
| 78 | David Hubbard | 22 | 2020-2026 | |
| 78 | Fred Koch# | 22 | 2052-2054 | |
| 78 | Ramón Rodríguez | 22 | 2032-2043 | |
| 83 | Guillermo Dettori# | 21 | 2044-2054 | |
| 83 | Vicente Gomillion | 21 | 2040-2045 | |
| 83 | Zahid Kashani | 21 | 2030-2043 | |
| 83 | Sherman Kline | 21 | 2042-2046 | |
| 83 | Arsenio Laurel | 21 | 2030-2040 | |
| 83 | Les Lumsden# | 21 | 2051-2054 | |
| 83 | Carl Nash | 21 | 2013-2014 | |
| 90 | Tommy Jones* | 20 | 2015-2036 | |
| 90 | Nick Leonard | 20 | 2017-2021 | |
| 90 | Nick Simmons | 20 | 2014-2022 | |
| 90 | Rafael Sánchez | 20 | 2025-2035 | |
| 94 | Kelvin Abbott | 19 | 2032-2037 | |
| 94 | Sherman Davis | 19 | 2013-2022 | |
| 94 | Freek Derksen# | 19 | 2050-2054 | |
| 94 | Gabriel Montoya | 19 | 2037-2041 | |
| 94 | Miguel Morán | 19 | 2026-2032 | |
| 94 | Luis Rivas | 19 | 2015-2024 | |
| 94 | Daniel Ruíz | 19 | 2013-2017 |
