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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | António López | 105 | 2041-2050 | |
| 2 | Willie Cameron | 103 | 2016-2031 | |
| 3 | Danny Byrd | 93 | 2044-2050 | |
| 4 | Greg Beaver | 90 | 2016-2019 | |
| 5 | Patrick Ibáñez | 88 | 2035-2046 | |
| 6 | Louis McDowell | 81 | 2016-2028 | |
| 7 | Matt Davenport | 80 | 2029-2037 | |
| 7 | John Deemer | 80 | 2047-2050 | |
| 9 | Morris Nicholson | 79 | 2013-2021 | |
| 10 | Reynaldo Sánchez | 78 | 2024-2032 | |
| 11 | Earl Brown | 77 | 2023-2031 | |
| 11 | José Salinas | 77 | 2017-2027 | |
| 11 | Joel Walden | 77 | 2036-2043 | |
| 14 | Roy Alsobrook | 76 | 2028-2038 | |
| 14 | Gerrit Zuidgeest | 76 | 2035-2040 | |
| 16 | José Acevedo | 75 | 2013-2023 | |
| 16 | Norm Burris | 75 | 2016-2021 | |
| 16 | Katsumoto Ine# | 75 | 2047-2051 | |
| 16 | Steve Young | 75 | 2042-2049 | |
| 20 | King Fletcher | 73 | 2023-2030 | |
| 21 | Eduardo Capata | 72 | 2019-2032 | |
| 22 | Jorge Cedeño | 70 | 2033-2037 | |
| 23 | Héctor Barrera | 68 | 2039-2049 | |
| 23 | Fred Gunther | 68 | 2036-2040 | |
| 23 | Richard Meyer | 68 | 2018-2020 | |
| 26 | Raúl Andrés | 67 | 2016-2021 | |
| 26 | Ikaia Duncalf# | 67 | 2045-2051 | |
| 26 | Harrison Dunning | 67 | 2033-2037 | |
| 26 | Francisco Hernández | 67 | 2013-2018 | |
| 26 | Doug Ryan | 67 | 2016-2024 | |
| 31 | Aurélien Godet | 66 | 2015-2023 | |
| 31 | William Robinson# | 66 | 2048-2051 | |
| 33 | Kyuso Ageda | 65 | 2037-2043 | |
| 34 | Héctor Aguilar | 64 | 2030-2035 | |
| 34 | Mark Antrim# | 64 | 2047-2051 | |
| 34 | Bill Slaughter# | 64 | 2048-2051 | |
| 34 | Bob Wheelock# | 64 | 2043-2051 | |
| 38 | Gregory Gary | 63 | 2016-2023 | |
| 38 | José Marín | 63 | 2034-2041 | |
| 40 | Kane Hallworth# | 62 | 2044-2048 | |
| 40 | Harry Stuterberg | 62 | 2034-2047 | |
| 42 | Stanley Kent | 61 | 2030-2041 | |
| 43 | José García# | 60 | 2046-2049 | |
| 43 | José Ramírez | 60 | 2016-2018 | |
| 43 | Harvey Wyles | 60 | 2038-2047 | |
| 46 | Francisco Barrios | 59 | 2020-2033 | |
| 46 | Dave Conley | 59 | 2015-2018 | |
| 46 | Brandeis Göller | 59 | 2017-2019 | |
| 46 | Ollie McDaniell | 59 | 2033-2037 | |
| 46 | Arturo Mesa | 59 | 2037-2040 | |
| 51 | Melvin Lee | 58 | 2015-2018 | |
| 51 | Doruk Oyan | 58 | 2016-2018 | |
| 53 | Kendarian Handy-Holly | 57 | 2030-2038 | |
| 53 | Marcos Mesa | 57 | 2023-2030 | |
| 53 | Claudio Ortega# | 57 | 2043-2050 | |
| 56 | Parker Larsen# | 56 | 2046-2051 | |
| 56 | Zuo-lin Liang# | 56 | 2040-2047 | |
| 56 | José Lucero | 56 | 2035-2046 | |
| 56 | Henri Pollini | 56 | 2019-2030 | |
| 56 | Santiago Ramírez | 56 | 2032-2042 | |
| 61 | Riley Evans | 55 | 2037-2042 | |
| 61 | Cisco Ortíz | 55 | 2026-2035 | |
| 61 | Han Sawallisch | 55 | 2016-2020 | |
| 61 | Jeffrey van Veldhuizen | 55 | 2034-2041 | |
| 65 | Shihab bin Salim | 54 | 2037-2040 | |
| 65 | Carlos Domínguez | 54 | 2026-2032 | |
| 65 | Javier Soto | 54 | 2040-2044 | |
| 68 | Scotty Bingham | 53 | 2036-2048 | |
| 68 | Ralph Haggerty | 53 | 2029-2038 | |
| 68 | Max Moore | 53 | 2017-2018 | |
| 71 | Cecil Drabek | 52 | 2043-2051 | |
| 71 | Cisco Pérez | 52 | 2034-2038 | |
| 73 | Herman Barnes | 51 | 2017-2029 | |
| 73 | Claude Khatoon | 51 | 2042-2048 | |
| 73 | Larry Souder | 51 | 2035-2040 | |
| 76 | Dave Haynes | 50 | 2034-2041 | |
| 76 | Jason Huggins | 50 | 2037-2046 | |
| 76 | Chae-seong Kim | 50 | 2023-2033 | |
| 76 | Brandon Sorkin | 50 | 2034-2039 | |
| 80 | Wop Baars | 49 | 2032-2041 | |
| 80 | Miguel Cabañas | 49 | 2029-2035 | |
| 80 | Broderick Evans | 49 | 2036-2045 | |
| 80 | Tony Hernández | 49 | 2016-2020 | |
| 80 | Shoichi Iwata | 49 | 2045-2049 | |
| 80 | Albert Sierra | 49 | 2034-2041 | |
| 80 | Millard Taylor | 49 | 2023-2033 | |
| 87 | Victor Brey | 48 | 2021-2028 | |
| 87 | Jesús Garces | 48 | 2030-2035 | |
| 87 | Ray Goolsby | 48 | 2031-2045 | |
| 87 | Andrés Martínez | 48 | 2013-2019 | |
| 87 | Paul O'Callahan | 48 | 2017-2025 | |
| 87 | José Ortíz | 48 | 2026-2037 | |
| 87 | Jessie Young | 48 | 2037-2043 | |
| 94 | Benjamin Busto | 47 | 2029-2038 | |
| 94 | Javier Contreras | 47 | 2034-2037 | |
| 94 | Norberto Flores | 47 | 2027-2033 | |
| 94 | Jesús Franco | 47 | 2032-2038 | |
| 94 | Jesús González | 47 | 2013-2018 | |
| 94 | Mike Hess | 47 | 2043-2047 | |
| 94 | Tom Howard | 47 | 2016-2017 |
