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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Manuel Villarreal | 215 | 2013-2022 | |
| 2 | Wilbur Davis | 160 | 2026-2041 | |
| 3 | Jorge Herrera# | 127 | 2035-2044 | |
| 4 | Karl Schultz | 102 | 2020-2032 | |
| 5 | Pedro Willis | 92 | 2013-2024 | |
| 6 | Neil Lawson | 83 | 2016-2031 | |
| 7 | Pancho García | 78 | 2013-2025 | |
| 8 | Michael Malloy# | 76 | 2027-2042 | |
| 9 | Melvin Castro* | 65 | 2020-2035 | |
| 10 | Terrence Eler | 63 | 2018-2033 | |
| 11 | Stanley Belote | 61 | 2027-2037 | |
| 11 | Bernardo Elías | 61 | 2019-2032 | |
| 13 | Alfredo Martínez | 56 | 2025-2041 | |
| 14 | James Murray | 54 | 2013-2022 | |
| 15 | Glyn Bolasky | 52 | 2029-2044 | |
| 15 | Rob Brooks# | 52 | 2036-2044 | |
| 17 | Fernando Soto# | 51 | 2038-2044 | |
| 18 | Armando Esparza | 50 | 2015-2027 | |
| 19 | Chris Payling# | 49 | 2028-2044 | |
| 19 | Jur Prokop# | 49 | 2036-2044 | |
| 21 | Mariano Juderías# | 48 | 2042-2044 | |
| 22 | Jerry Harris | 46 | 2013-2019 | |
| 23 | Robert Adams | 45 | 2023-2029 | |
| 23 | Miguel Chávez | 45 | 2017-2021 | |
| 23 | Jasper Morrison# | 45 | 2034-2043 | |
| 23 | Ramón Souza | 45 | 2018-2029 | |
| 23 | Marcos Zúñiga | 45 | 2014-2020 | |
| 28 | Jesús Vargas# | 44 | 2029-2044 | |
| 29 | Arturo Hernández | 39 | 2013-2019 | |
| 30 | Pedro Castillo | 37 | 2028-2032 | |
| 30 | Mike Gardner | 37 | 2018-2032 | |
| 30 | Tae-cho Han# | 37 | 2031-2044 | |
| 30 | Craig Woods# | 37 | 2037-2044 | |
| 34 | Rafael Arredondo | 36 | 2024-2032 | |
| 35 | Tim Hargrove | 35 | 2016-2027 | |
| 35 | Eisse van Opdorp# | 35 | 2038-2044 | |
| 37 | Manuel Carmona# | 32 | 2025-2042 | |
| 38 | Enrique Marroquín | 31 | 2020-2032 | |
| 38 | Daniel McCoy# | 31 | 2032-2044 | |
| 40 | Harry Cornelis# | 29 | 2040-2044 | |
| 40 | Wilfred McLaughlin* | 29 | 2018-2033 | |
| 40 | José Ruíz | 29 | 2027-2038 | |
| 40 | Mal Wadley | 29 | 2015-2028 | |
| 44 | Félix Pérez | 28 | 2013-2022 | |
| 44 | Guillermo Romero | 28 | 2013-2021 | |
| 46 | Gilberto Ocasio# | 27 | 2036-2044 | |
| 46 | Pedro Vázquez | 27 | 2023-2036 | |
| 48 | León Castillo# | 26 | 2039-2044 | |
| 48 | Jérôme Masson | 26 | 2029-2038 | |
| 48 | Ken Norman | 26 | 2015-2022 | |
| 48 | Michael Witt | 26 | 2037-2043 | |
| 52 | Joey Jones | 25 | 2019-2031 | |
| 52 | Rick Mayfield | 25 | 2028-2036 | |
| 52 | Jon Osterman | 25 | 2028-2044 | |
| 55 | Iiri Haapajarvi# | 23 | 2039-2044 | |
| 55 | Raúl Robles | 23 | 2017-2025 | |
| 55 | Yoichibei Sato | 23 | 2026-2033 | |
| 55 | Iván Vega | 23 | 2023-2037 | |
| 59 | David Breitling | 22 | 2028-2031 | |
| 59 | Brad Elmore | 22 | 2015-2025 | |
| 59 | David Hubbard | 22 | 2020-2026 | |
| 59 | Ramón Rodríguez | 22 | 2032-2043 | |
| 63 | Vicente Gomillion# | 21 | 2040-2044 | |
| 63 | Zahid Kashani | 21 | 2030-2043 | |
| 63 | Sherman Kline# | 21 | 2042-2044 | |
| 63 | Arsenio Laurel | 21 | 2030-2040 | |
| 63 | Carl Nash | 21 | 2013-2014 | |
| 68 | Tommy Jones* | 20 | 2015-2036 | |
| 68 | Nick Leonard | 20 | 2017-2021 | |
| 68 | Rafael Sánchez | 20 | 2025-2035 | |
| 68 | Nick Simmons | 20 | 2014-2022 | |
| 72 | Kelvin Abbott | 19 | 2032-2037 | |
| 72 | Sherman Davis | 19 | 2013-2022 | |
| 72 | Gabriel Montoya | 19 | 2037-2041 | |
| 72 | Miguel Morán | 19 | 2026-2032 | |
| 72 | Luis Rivas | 19 | 2015-2024 | |
| 72 | Daniel Ruíz | 19 | 2013-2017 | |
| 78 | Ye Der | 18 | 2018-2028 | |
| 78 | Shohei Kiyomizu | 18 | 2025-2034 | |
| 80 | Bill Burgess | 17 | 2015-2025 | |
| 80 | Virgil Eberle | 17 | 2017-2025 | |
| 80 | Pedro Gutiérrez | 17 | 2032-2039 | |
| 80 | Rafael Martínez# | 17 | 2043-2044 | |
| 80 | Alexis Raimbault | 17 | 2030-2042 | |
| 80 | Manoo Satyavrat | 17 | 2027-2042 | |
| 80 | Stanley van de Ven | 17 | 2031-2037 | |
| 80 | Quincy Wass# | 17 | 2042-2044 | |
| 88 | Kevin Baxter | 16 | 2031-2041 | |
| 88 | Manuel Domínguez | 16 | 2026-2029 | |
| 88 | Francisco García | 16 | 2027-2038 | |
| 88 | Shun Komatsu | 16 | 2035-2042 | |
| 88 | Martín Pliego# | 16 | 2042-2044 | |
| 88 | Robbie Roach | 16 | 2016-2028 | |
| 94 | Gerrie Bond# | 15 | 2036-2044 | |
| 94 | Jason Powell | 15 | 2013-2021 | |
| 94 | Roberto Rodríguez | 15 | 2014-2022 | |
| 94 | Eric Thackston | 15 | 2026-2035 | |
| 98 | Casey Cavell | 14 | 2028-2030 | |
| 98 | Earl Ellis | 14 | 2013-2021 | |
| 98 | Chriss Mann | 14 | 2019-2032 |
