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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Manuel Villarreal | 228 | 2013-2022 | |
| 2 | Wilbur Davis | 161 | 2026-2041 | |
| 3 | Karl Schultz | 102 | 2020-2032 | |
| 4 | Pedro Willis | 92 | 2013-2024 | |
| 5 | Pancho García | 85 | 2013-2025 | |
| 5 | Jorge Herrera# | 85 | 2035-2042 | |
| 7 | Neil Lawson | 83 | 2016-2031 | |
| 8 | Terrence Eler | 76 | 2018-2033 | |
| 8 | Michael Malloy# | 76 | 2027-2042 | |
| 10 | Melvin Castro* | 65 | 2020-2035 | |
| 11 | Ramón Souza | 63 | 2018-2029 | |
| 12 | Stanley Belote | 61 | 2027-2037 | |
| 12 | Bernardo Elías | 61 | 2019-2032 | |
| 14 | Armando Esparza | 60 | 2015-2027 | |
| 15 | Tae-cho Han# | 59 | 2031-2042 | |
| 15 | Tim Hargrove | 59 | 2016-2027 | |
| 17 | Alfredo Martínez | 56 | 2025-2041 | |
| 18 | Manuel Carmona# | 54 | 2025-2042 | |
| 18 | James Murray | 54 | 2013-2022 | |
| 20 | Glyn Bolasky# | 52 | 2029-2041 | |
| 21 | Chris Payling# | 49 | 2028-2042 | |
| 22 | Jerry Harris | 46 | 2013-2019 | |
| 23 | Robert Adams | 45 | 2023-2029 | |
| 23 | Miguel Chávez | 45 | 2017-2021 | |
| 23 | Jasper Morrison# | 45 | 2034-2042 | |
| 23 | Marcos Zúñiga | 45 | 2014-2020 | |
| 27 | Rob Brooks# | 44 | 2036-2042 | |
| 28 | Daniel McCoy# | 43 | 2032-2042 | |
| 29 | Arturo Hernández | 39 | 2013-2019 | |
| 30 | Pedro Castillo | 37 | 2028-2032 | |
| 30 | Mike Gardner | 37 | 2018-2032 | |
| 32 | Rafael Arredondo | 36 | 2024-2032 | |
| 33 | Eisse van Opdorp# | 35 | 2038-2042 | |
| 34 | Enrique Marroquín | 31 | 2020-2032 | |
| 35 | Shun Komatsu# | 30 | 2035-2042 | |
| 36 | Wilfred McLaughlin* | 29 | 2018-2033 | |
| 36 | José Ruíz | 29 | 2027-2038 | |
| 36 | Jesús Vargas# | 29 | 2029-2042 | |
| 36 | Mal Wadley | 29 | 2015-2028 | |
| 40 | Félix Pérez | 28 | 2013-2022 | |
| 40 | Guillermo Romero | 28 | 2013-2021 | |
| 42 | Pedro Vázquez | 27 | 2023-2036 | |
| 43 | Jérôme Masson | 26 | 2029-2038 | |
| 43 | Ken Norman | 26 | 2015-2022 | |
| 43 | Michael Witt# | 26 | 2037-2042 | |
| 46 | Joey Jones | 25 | 2019-2031 | |
| 46 | Rick Mayfield | 25 | 2028-2036 | |
| 46 | Jon Osterman# | 25 | 2028-2042 | |
| 49 | Ed Adams | 24 | 2027-2032 | |
| 49 | Tommy Jones* | 24 | 2015-2036 | |
| 49 | Joey Morgan | 24 | 2021-2026 | |
| 49 | Fernando Soto# | 24 | 2038-2042 | |
| 53 | Raúl Robles | 23 | 2017-2025 | |
| 53 | Yoichibei Sato | 23 | 2026-2033 | |
| 53 | Iván Vega | 23 | 2023-2037 | |
| 56 | David Breitling | 22 | 2028-2031 | |
| 56 | Brad Elmore | 22 | 2015-2025 | |
| 56 | David Hubbard | 22 | 2020-2026 | |
| 59 | Abílio Conceio | 21 | 2013-2026 | |
| 59 | Vicente Gomillion# | 21 | 2040-2042 | |
| 59 | Zahid Kashani# | 21 | 2030-2042 | |
| 59 | Arsenio Laurel# | 21 | 2030-2040 | |
| 59 | Carl Nash | 21 | 2013-2014 | |
| 59 | Lao Tian# | 21 | 2038-2042 | |
| 65 | Nick Leonard | 20 | 2017-2021 | |
| 65 | Luis Rivas | 20 | 2015-2024 | |
| 65 | Rafael Sánchez | 20 | 2025-2035 | |
| 65 | Nick Simmons | 20 | 2014-2022 | |
| 69 | Kelvin Abbott | 19 | 2032-2037 | |
| 69 | Sherman Davis | 19 | 2013-2022 | |
| 69 | Gabriel Montoya# | 19 | 2037-2041 | |
| 69 | Miguel Morán | 19 | 2026-2032 | |
| 69 | Daniel Ruíz | 19 | 2013-2017 | |
| 74 | Ye Der | 18 | 2018-2028 | |
| 74 | Juan González | 18 | 2021-2027 | |
| 74 | Shohei Kiyomizu | 18 | 2025-2034 | |
| 74 | Eddie Sachs# | 18 | 2032-2042 | |
| 78 | Bill Burgess | 17 | 2015-2025 | |
| 78 | Virgil Eberle | 17 | 2017-2025 | |
| 78 | Pedro Gutiérrez | 17 | 2032-2039 | |
| 78 | Gilberto Ocasio# | 17 | 2036-2042 | |
| 78 | Alexis Raimbault# | 17 | 2030-2042 | |
| 78 | Manoo Satyavrat# | 17 | 2027-2042 | |
| 78 | Stanley van de Ven | 17 | 2031-2037 | |
| 78 | Quincy Wass# | 17 | 2042-2042 | |
| 86 | Kevin Baxter | 16 | 2031-2041 | |
| 86 | Manuel Domínguez | 16 | 2026-2029 | |
| 86 | Francisco García | 16 | 2027-2038 | |
| 86 | Mariano Juderías# | 16 | 2042-2042 | |
| 86 | Robbie Roach | 16 | 2016-2028 | |
| 91 | Gerrie Bond# | 15 | 2036-2042 | |
| 91 | Jason Powell | 15 | 2013-2021 | |
| 91 | Roberto Rodríguez | 15 | 2014-2022 | |
| 91 | Eric Thackston | 15 | 2026-2035 | |
| 95 | Casey Cavell | 14 | 2028-2030 | |
| 95 | Harry Cornelis# | 14 | 2040-2042 | |
| 95 | Earl Ellis | 14 | 2013-2021 | |
| 95 | Chriss Mann | 14 | 2019-2032 | |
| 95 | Yu Miao# | 14 | 2036-2042 | |
| 95 | Albert Morán* | 14 | 2019-2035 |
