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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Todd Hines* | 2.52 | 2018-2032 | |
| 2 | Sozen Raikatuji | 2.59 | 2016-2023 | |
| 3 | Ryan Davis* | 2.62 | 2015-2026 | |
| 4 | Devin Hinton | 2.66 | 2013-2023 | |
| 5 | Ryan Ray | 2.79 | 2013-2021 | |
| 5 | Jesús Franco | 2.79 | 2026-2033 | |
| 7 | Sjaak Bonne# | 2.82 | 2025-2038 | |
| 7 | Iván García | 2.82 | 2021-2035 | |
| 9 | Jim Eliott* | 2.83 | 2014-2025 | |
| 10 | Guillermo García | 2.85 | 2013-2021 | |
| 11 | Ralph McKinney | 2.88 | 2019-2034 | |
| 12 | Lúcio Sánchez* | 2.90 | 2017-2031 | |
| 13 | Eric Matson# | 2.91 | 2028-2038 | |
| 14 | Yuri Volkers | 2.92 | 2013-2021 | |
| 15 | Jesús Caldero | 2.93 | 2018-2027 | |
| 16 | Bruce Wright | 2.95 | 2020-2030 | |
| 17 | Jorge Aguirre | 3.00 | 2015-2032 | |
| 18 | Jesús Gonzáles | 3.02 | 2019-2030 | |
| 18 | José Hernández | 3.02 | 2013-2023 | |
| 20 | Pedro Alejándrez | 3.04 | 2021-2034 | |
| 20 | Edwin Ellis | 3.04 | 2013-2019 | |
| 22 | Bill Oulton | 3.13 | 2021-2034 | |
| 22 | John Wilkins* | 3.13 | 2013-2028 | |
| 24 | Cris Mendoza | 3.15 | 2013-2029 | |
| 24 | John Kaufman | 3.15 | 2017-2032 | |
| 26 | Chester Henry | 3.16 | 2016-2023 | |
| 27 | Manuel Rojas | 3.17 | 2018-2028 | |
| 27 | Cordell Wilson | 3.17 | 2019-2030 | |
| 29 | Vincent Hall | 3.21 | 2020-2032 | |
| 29 | Ramón Ortega* | 3.21 | 2013-2028 | |
| 31 | Jorge Otero# | 3.22 | 2031-2037 | |
| 31 | Tom Reynolds* | 3.22 | 2015-2028 | |
| 33 | Yoriyoshi Yamamoto | 3.25 | 2016-2026 | |
| 34 | Edgardo Marín | 3.29 | 2013-2032 | |
| 35 | Alec Pittman | 3.31 | 2016-2030 | |
| 36 | Pedro Ortíz | 3.32 | 2020-2038 | |
| 37 | Eddie Kop# | 3.33 | 2025-2038 | |
| 38 | Gerardo Pagán# | 3.37 | 2027-2038 | |
| 39 | Aurelio López | 3.42 | 2022-2036 | |
| 40 | Juan Júlio | 3.45 | 2013-2026 | |
| 41 | Miguel Rubia# | 3.47 | 2029-2038 | |
| 42 | Raúl Gómez | 3.48 | 2027-2033 | |
| 42 | Wayne Craig | 3.48 | 2018-2030 | |
| 42 | Ilie Paunescu | 3.48 | 2016-2035 | |
| 45 | Curtis Fields | 3.49 | 2016-2024 | |
| 45 | George Frazier | 3.49 | 2019-2037 | |
| 45 | John Dempsey | 3.49 | 2022-2037 | |
| 48 | Tony Alfonso# | 3.52 | 2033-2038 | |
| 49 | Pat Farrell | 3.53 | 2013-2022 | |
| 49 | Andrew Moody# | 3.53 | 2032-2038 | |
| 51 | Wes Hamm | 3.55 | 2021-2037 | |
| 51 | Alejandro Guerra# | 3.55 | 2027-2037 | |
| 51 | Billy Crawford | 3.55 | 2014-2025 | |
| 54 | Germán Rodríguez# | 3.59 | 2024-2038 | |
| 55 | Wayne Hurst | 3.63 | 2015-2024 | |
| 56 | Fraser Cuevas | 3.64 | 2020-2032 | |
| 57 | Raúl Areola | 3.65 | 2020-2033 | |
| 58 | Keisuke Nishida | 3.66 | 2029-2036 | |
| 59 | Burt Booth | 3.67 | 2013-2026 | |
| 60 | José García | 3.69 | 2022-2035 | |
| 61 | Enrique Cortéz | 3.70 | 2022-2032 | |
| 62 | Juan Torres | 3.71 | 2023-2029 | |
| 63 | Kirby Brown | 3.76 | 2017-2029 | |
| 64 | José Flores | 3.80 | 2019-2029 | |
| 65 | Bill Fletcher | 3.81 | 2018-2025 | |
| 65 | Kenny Aarnoutse# | 3.81 | 2032-2038 | |
| 65 | Mimosa Joseph | 3.81 | 2023-2035 | |
| 68 | Miguel Castillo | 3.82 | 2013-2020 | |
| 69 | Luis Flores | 3.83 | 2024-2033 | |
| 70 | Ramón Molina | 3.89 | 2026-2034 | |
| 71 | Jaime van de Weideven# | 3.91 | 2022-2038 | |
| 72 | Yoo-chul Mun# | 3.97 | 2031-2038 | |
| 73 | Mario Peńa | 3.98 | 2013-2023 | |
| 74 | Enrique Magana | 4.04 | 2013-2019 | |
| 75 | Josef van der Poel# | 4.05 | 2019-2035 | |
| 76 | Vern Camp | 4.08 | 2013-2022 | |
| 77 | Addie Samson | 4.11 | 2021-2035 | |
| 78 | Giovanni Mireles# | 4.16 | 2029-2038 | |
| 79 | Sam Mooney# | 4.18 | 2028-2038 | |
| 80 | Natalino Golaio# | 4.21 | 2023-2037 | |
| 81 | Sy-ing Tah# | 4.23 | 2030-2038 | |
| 82 | Tobías Pérez# | 4.27 | 2024-2037 | |
| 83 | Pablo De La Torre | 4.31 | 2021-2038 | |
| 84 | Elroy Thompkins# | 4.32 | 2029-2038 | |
| 85 | Yin-fat Foong | 4.36 | 2017-2029 | |
| 85 | Cole Hall | 4.36 | 2013-2027 | |
| 87 | Calvin Beck | 4.45 | 2026-2033 | |
| 88 | Luis Peńa | 4.54 | 2025-2037 | |
| 88 | Gerald Keller# | 4.54 | 2030-2036 | |
| 90 | Edgar Martínez | 4.78 | 2013-2021 | |
| 91 | Pedro Ramírez | 5.08 | 2023-2032 |
