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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Darryl Gordon | 1.50 | 2017-2021 | |
| 2 | Dave Tomlinson | 1.59 | 2017-2026 | |
| 3 | Randy Hoffman | 1.69 | 2017-2024 | |
| 3 | Brantford Winstworth III# | 1.69 | 2030-2037 | |
| 5 | Russ Horne# | 1.72 | 2024-2036 | |
| 5 | Kyle Lewis | 1.72 | 2015-2026 | |
| 7 | Peter Rivers | 1.82 | 2018-2020 | |
| 8 | Eric Matson# | 1.85 | 2027-2037 | |
| 9 | Ryan Peterson# | 1.91 | 2026-2036 | |
| 10 | José Galindo | 1.96 | 2015-2018 | |
| 11 | Juan Guillén# | 2.02 | 2026-2037 | |
| 12 | Tyler MacHugh | 2.12 | 2025-2032 | |
| 12 | John Riggleman# | 2.12 | 2026-2037 | |
| 14 | Enrique Castro | 2.15 | 2030-2037 | |
| 15 | Raúl Melro | 2.17 | 2027-2028 | |
| 15 | Leslie Brooks | 2.17 | 2021-2030 | |
| 17 | Luis Peña | 2.23 | 2025-2032 | |
| 18 | Willie Dustice# | 2.35 | 2031-2035 | |
| 19 | Dan Mitchell | 2.36 | 2020-2025 | |
| 20 | Anthony Ledesma# | 2.37 | 2030-2037 | |
| 21 | Shunen Takahashi | 2.41 | 2023-2035 | |
| 22 | Jorge Garza | 2.44 | 2022-2031 | |
| 23 | Eduardo Molina | 2.45 | 2022-2033 | |
| 24 | Ilie Paunescu | 2.56 | 2018-2033 | |
| 25 | Jeff Reynolds | 2.57 | 2018-2020 | |
| 26 | Allen Blair | 2.59 | 2017-2031 | |
| 27 | Ryan Ray | 2.60 | 2017-2021 | |
| 28 | Jim Dixon | 2.63 | 2016-2027 | |
| 29 | Chip Bishop | 2.69 | 2015-2030 | |
| 30 | Ismael Barrios | 2.75 | 2024-2026 | |
| 31 | Richard Sykes | 2.78 | 2017-2027 | |
| 31 | Brian Wheeler | 2.78 | 2019-2024 | |
| 33 | Tom McKee# | 2.80 | 2031-2036 | |
| 34 | Gary Bailey | 2.81 | 2015-2032 | |
| 35 | Stuart Lee | 2.82 | 2018-2025 | |
| 36 | Alfonso Zapata | 2.83 | 2022-2033 | |
| 37 | Rémi Ribeiro# | 2.86 | 2030-2033 | |
| 38 | Clemente Prista | 2.87 | 2018-2022 | |
| 39 | Roger Garrett | 2.91 | 2016-2024 | |
| 40 | Juan Júlio | 2.93 | 2015-2026 | |
| 41 | Shigemasa Horiuchi | 2.95 | 2017-2031 | |
| 42 | David Buchanan# | 3.00 | 2029-2037 | |
| 42 | Carlos Sánchez | 3.00 | 2021-2028 | |
| 44 | Walt Coffman# | 3.02 | 2026-2035 | |
| 45 | Raúl Areola | 3.03 | 2022-2032 | |
| 46 | Jeff Mahl# | 3.05 | 2033-2037 | |
| 47 | Javier Desdin# | 3.06 | 2026-2037 | |
| 48 | Billy Crawford | 3.07 | 2019-2024 | |
| 49 | Félix Jiménez | 3.08 | 2022-2026 | |
| 50 | Michael Machen# | 3.09 | 2029-2036 | |
| 50 | Faisal bin Nabeel# | 3.09 | 2032-2037 | |
| 50 | Júlio Rodríguez# | 3.09 | 2023-2037 | |
| 53 | Hermenegildo Beliago# | 3.11 | 2027-2037 | |
| 54 | Domingo Ramírez# | 3.13 | 2023-2035 | |
| 55 | Quentin Bowers# | 3.15 | 2027-2037 | |
| 55 | Davis Sawyer# | 3.15 | 2034-2037 | |
| 55 | Alfonso Miranda | 3.15 | 2022-2031 | |
| 58 | Víctor Padilla | 3.18 | 2017-2020 | |
| 58 | Kevin Nogilny# | 3.18 | 2031-2035 | |
| 60 | Pedro Alejándrez | 3.20 | 2020-2034 | |
| 60 | Addie Samson | 3.20 | 2024-2034 | |
| 62 | Jim Roberts | 3.23 | 2016-2020 | |
| 63 | Jorge Castillo | 3.24 | 2020-2030 | |
| 64 | Armando Martínez | 3.26 | 2018-2020 | |
| 65 | Tetsuzan Kaneko | 3.30 | 2018-2025 | |
| 66 | Kent Clement | 3.32 | 2021-2032 | |
| 67 | Hunter Wilson | 3.35 | 2022-2027 | |
| 67 | Keisuke Nishida | 3.35 | 2027-2031 | |
| 69 | Alexis Zambaco# | 3.36 | 2028-2037 | |
| 70 | Tim Powell | 3.39 | 2015-2020 | |
| 70 | Dale Hamilton# | 3.39 | 2029-2037 | |
| 72 | Roberto De La Cruz | 3.41 | 2022-2031 | |
| 73 | Zalontae Hillary# | 3.43 | 2031-2037 | |
| 74 | Eddie Kop# | 3.44 | 2026-2037 | |
| 75 | Shawn Williams# | 3.51 | 2030-2036 | |
| 75 | Markus Morgan | 3.51 | 2015-2020 | |
| 77 | Javier Dávila | 3.52 | 2026-2031 | |
| 77 | Bill Fletcher | 3.52 | 2018-2027 | |
| 79 | Fernando Padilla# | 3.53 | 2028-2033 | |
| 79 | Pedro Ritodíaz | 3.53 | 2015-2024 | |
| 79 | Toddster Gordo# | 3.53 | 2029-2030 | |
| 82 | Art Adams | 3.59 | 2021-2030 | |
| 83 | George Eisenhauer# | 3.60 | 2028-2034 | |
| 84 | William MacKnight | 3.64 | 2022-2028 | |
| 85 | Juan Cardenas | 3.66 | 2029-2037 | |
| 85 | Adrián Fierro | 3.66 | 2020-2034 | |
| 87 | Leroy Moody | 3.68 | 2025-2032 | |
| 88 | António Castillo# | 3.69 | 2027-2036 | |
| 88 | Nathaniel Riley | 3.69 | 2026-2027 | |
| 90 | Roderick Rhodes | 3.76 | 2015-2030 | |
| 91 | Cordell Wilson | 3.78 | 2018-2023 | |
| 92 | Pedro Valdéz# | 3.79 | 2023-2037 | |
| 92 | Ron Manning# | 3.79 | 2029-2037 | |
| 92 | Rafael Cardona | 3.79 | 2021-2031 | |
| 95 | Greg White | 3.82 | 2015-2028 | |
| 96 | Will Hunting# | 3.86 | 2030-2037 | |
| 96 | John Wilkins* | 3.86 | 2018-2029 | |
| 98 | Rusty Swanson# | 3.89 | 2026-2035 | |
| 99 | Cole Hall | 3.90 | 2015-2025 | |
| 99 | Yusuke Chikafuji | 3.90 | 2024-2032 |
