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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | António González# | 83 | 2024-2037 | |
| 2 | Hank Wilder | 82 | 2024-2029 | |
| 3 | Jesús Cabañe | 65 | 2022-2031 | |
| 4 | Arnold Griffith | 56 | 2015-2025 | |
| 5 | Richard Jost# | 48 | 2029-2037 | |
| 6 | Luis Luquín# | 46 | 2029-2037 | |
| 7 | Craig Morgan# | 44 | 2032-2036 | |
| 8 | Arnold Giroux# | 40 | 2027-2033 | |
| 9 | Quindarious Monday# | 38 | 2033-2037 | |
| 10 | Hugh Hill# | 32 | 2034-2037 | |
| 11 | Joe Craig | 31 | 2023-2032 | |
| 12 | Pedro Cruz | 30 | 2016-2022 | |
| 13 | Armando Alvarado | 29 | 2019-2034 | |
| 13 | Keiran Calleson# | 29 | 2034-2037 | |
| 13 | Alden Wiley | 29 | 2015-2031 | |
| 16 | Cam MacIntosh# | 28 | 2030-2037 | |
| 16 | Jesús Ruano# | 28 | 2032-2036 | |
| 18 | Kumanosuke Abe | 27 | 2024-2032 | |
| 18 | Sean Davis | 27 | 2017-2030 | |
| 18 | Elian Gonzalez | 27 | 2030-2032 | |
| 21 | Fernando López | 26 | 2016-2021 | |
| 22 | Lionel McCloud | 24 | 2028-2035 | |
| 23 | Randy Bowen | 23 | 2022-2027 | |
| 23 | Gonzalo López* | 23 | 2016-2025 | |
| 23 | Guillermo Montoya | 23 | 2016-2021 | |
| 26 | Ed Anderson | 20 | 2015-2025 | |
| 26 | Eugene Parrish | 20 | 2015-2024 | |
| 26 | Freddy Torres# | 20 | 2030-2037 | |
| 29 | Nelson Jaramillo# | 19 | 2029-2036 | |
| 30 | Tony Hernández | 18 | 2022-2032 | |
| 31 | David Martínez | 17 | 2015-2028 | |
| 31 | José Paz | 17 | 2025-2031 | |
| 33 | Lester Kwiatkowski# | 16 | 2031-2037 | |
| 33 | Jesús Lazcano# | 16 | 2033-2037 | |
| 35 | Evan Adams | 15 | 2024-2028 | |
| 35 | Augusto Encarnación# | 15 | 2029-2036 | |
| 35 | Chris Etheridge | 15 | 2025-2035 | |
| 35 | Pablo Marrero | 15 | 2027-2032 | |
| 35 | Bill McCarty | 15 | 2015-2020 | |
| 40 | Kunimichi Chikafuji | 14 | 2024-2033 | |
| 40 | Colm Goodwill# | 14 | 2030-2036 | |
| 40 | Locke Lamora | 14 | 2028-2030 | |
| 40 | Ernest Miller | 14 | 2015-2021 | |
| 40 | Félix Rodríguez | 14 | 2015-2021 | |
| 40 | Carlos Vera | 14 | 2015-2021 | |
| 40 | Ted Young | 14 | 2015-2023 | |
| 47 | Pau Arria# | 13 | 2027-2036 | |
| 47 | Steve Brewer | 13 | 2015-2019 | |
| 47 | Carlos Campos# | 13 | 2033-2036 | |
| 50 | Forrest McCooke | 12 | 2021-2027 | |
| 50 | Vincente Rotham | 12 | 2026-2030 | |
| 52 | Mesa Altuve | 11 | 2028-2032 | |
| 52 | Mike Burns | 11 | 2020-2032 | |
| 52 | Arturo Guzmán | 11 | 2015-2021 | |
| 52 | Mark McClear | 11 | 2015-2029 | |
| 52 | Jesús Quintanilla | 11 | 2022-2029 | |
| 52 | Naohiro Sakai | 11 | 2026-2035 | |
| 52 | Nuygen Vuong# | 11 | 2029-2031 | |
| 59 | Micah Coffey | 10 | 2025-2034 | |
| 59 | Alexei Ponikarov# | 10 | 2035-2037 | |
| 61 | Mike Houston# | 9 | 2033-2034 | |
| 61 | Dave Knight | 9 | 2017-2021 | |
| 61 | Jim Lee | 9 | 2021-2022 | |
| 61 | Armond Merlin | 9 | 2029-2033 | |
| 61 | Ethan Stanford | 9 | 2025-2032 | |
| 66 | Edgar Cantú | 8 | 2015-2019 | |
| 66 | Vincent Crane | 8 | 2024-2036 | |
| 66 | Alain Grosjean# | 8 | 2036-2037 | |
| 66 | José Torres# | 8 | 2034-2036 | |
| 70 | Tom Christensen | 7 | 2023-2024 | |
| 70 | Cristo González | 7 | 2022-2033 | |
| 70 | Mike Green | 7 | 2018-2028 | |
| 70 | Rodrigo Luna | 7 | 2015-2018 | |
| 70 | Jason Nicholson | 7 | 2015-2019 | |
| 70 | Wesley Osborne | 7 | 2015-2016 | |
| 70 | Carlos Rodríguez | 7 | 2017-2018 | |
| 70 | Reece White | 7 | 2015-2020 | |
| 78 | Tom Bancroft# | 6 | 2035-2037 | |
| 78 | Mike Brown | 6 | 2017-2024 | |
| 78 | Cristián Coronado# | 6 | 2033-2037 | |
| 78 | Gabriel Díaz | 6 | 2026-2029 | |
| 78 | David Gómez | 6 | 2026-2030 | |
| 78 | Rod Jones | 6 | 2023-2027 | |
| 78 | Ángel López | 6 | 2023-2027 | |
| 78 | Javier López# | 6 | 2035-2037 | |
| 78 | Carlos Maldonado | 6 | 2026-2033 | |
| 78 | Ernie McPherson | 6 | 2020-2024 | |
| 78 | Travis Newsome | 6 | 2021-2031 | |
| 78 | Munemori Ohara | 6 | 2020-2033 | |
| 78 | Job Pels | 6 | 2024-2030 | |
| 78 | Panas Pletnev# | 6 | 2033-2037 | |
| 78 | Monte Pollard | 6 | 2015-2020 | |
| 78 | Enrico Sánchez# | 6 | 2035-2037 | |
| 78 | Royce Smith | 6 | 2015-2018 | |
| 78 | Xavier Vásquez | 6 | 2023-2031 | |
| 78 | Jonathan Widdop | 6 | 2021-2025 | |
| 97 | Brent Barlow | 5 | 2017-2022 | |
| 97 | Vance Cannon | 5 | 2015-2020 | |
| 97 | Brit Davis# | 5 | 2035-2036 | |
| 97 | Tomás Guillén | 5 | 2019-2023 |
