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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Mario Ramos# | 26 | 2022-2037 | |
| 2 | Javier Sánchez# | 22 | 2023-2037 | |
| 3 | Steve Ingram | 21 | 2014-2029 | |
| 3 | Obidiah Lewis# | 21 | 2028-2037 | |
| 5 | Jesús Vargas# | 18 | 2029-2037 | |
| 6 | Wilbur Davis# | 17 | 2027-2037 | |
| 6 | Bart Lewis | 17 | 2019-2036 | |
| 6 | Jesús Reyes | 17 | 2023-2032 | |
| 6 | Mike Silver* | 17 | 2014-2027 | |
| 10 | Chad Armstrong* | 16 | 2014-2028 | |
| 10 | Luis Muńóz | 16 | 2019-2025 | |
| 10 | Michael Neely | 16 | 2016-2029 | |
| 10 | Manoo Satyavrat# | 16 | 2029-2037 | |
| 14 | José Corona# | 15 | 2028-2037 | |
| 15 | Ralph Cranford# | 14 | 2030-2036 | |
| 15 | Bob Dickerson | 14 | 2019-2037 | |
| 15 | Herman Hayes | 14 | 2016-2029 | |
| 15 | Tsai Ng# | 14 | 2030-2037 | |
| 15 | Emílio Sáenz | 14 | 2014-2025 | |
| 15 | David Smith | 14 | 2018-2034 | |
| 21 | Dewitt Hopper# | 13 | 2028-2037 | |
| 21 | Salvador Trevino# | 13 | 2028-2037 | |
| 23 | Stefano Gaddi | 12 | 2023-2032 | |
| 23 | Todd Henry | 12 | 2022-2031 | |
| 23 | Hugh Mungus# | 12 | 2027-2037 | |
| 26 | Gustavo Cortéz | 11 | 2023-2034 | |
| 26 | Félix López | 11 | 2021-2033 | |
| 26 | Carlos Padilla | 11 | 2024-2036 | |
| 26 | Chris Rice | 11 | 2015-2026 | |
| 26 | Ramiro Salazar | 11 | 2016-2027 | |
| 26 | Yu-zeng Si# | 11 | 2032-2037 | |
| 32 | Edwin Church | 10 | 2020-2034 | |
| 32 | Count Dante# | 10 | 2025-2037 | |
| 32 | John Downing | 10 | 2014-2034 | |
| 32 | Tomás Martínez | 10 | 2031-2036 | |
| 32 | Enrique Pérez* | 10 | 2018-2029 | |
| 32 | Gabriel Pérez# | 10 | 2023-2034 | |
| 32 | Sam Quint | 10 | 2029-2034 | |
| 32 | Ramón Souza | 10 | 2015-2027 | |
| 32 | Bertrand Sunter | 10 | 2017-2020 | |
| 32 | Hank Wilder | 10 | 2019-2032 | |
| 42 | Avon Barksdale | 9 | 2023-2033 | |
| 42 | Bartolo Benítez | 9 | 2021-2033 | |
| 42 | Dylan Carson# | 9 | 2028-2037 | |
| 42 | Steve Dunn | 9 | 2018-2028 | |
| 42 | Carl Good | 9 | 2017-2021 | |
| 42 | Júlio Gruzmán | 9 | 2018-2022 | |
| 42 | David Henderson | 9 | 2016-2025 | |
| 42 | Júlio Maldonado | 9 | 2020-2025 | |
| 42 | Daniel McCoy# | 9 | 2032-2037 | |
| 42 | James Murray | 9 | 2015-2022 | |
| 42 | Carlos Ortega | 9 | 2018-2025 | |
| 42 | Brad Perry | 9 | 2015-2027 | |
| 42 | Nathan Tanner# | 9 | 2024-2036 | |
| 42 | Pedro Vázquez | 9 | 2025-2036 | |
| 42 | Mal Wadley | 9 | 2017-2028 | |
| 42 | Ryan Westlake | 9 | 2019-2030 | |
| 58 | Cliff Aldridge | 8 | 2022-2031 | |
| 58 | Scotty Anderson | 8 | 2022-2029 | |
| 58 | António Boccanegra# | 8 | 2028-2036 | |
| 58 | Keith Bridges | 8 | 2018-2024 | |
| 58 | Mario Castillo# | 8 | 2023-2037 | |
| 58 | Melvin Castro | 8 | 2020-2035 | |
| 58 | Eric D'Angle | 8 | 2022-2030 | |
| 58 | Terrence Eler | 8 | 2019-2032 | |
| 58 | Arnold Giroux# | 8 | 2027-2037 | |
| 58 | Ramón Gómez | 8 | 2021-2031 | |
| 58 | Tae-cho Han# | 8 | 2033-2037 | |
| 58 | Chris McKinney | 8 | 2024-2034 | |
| 58 | Fernando Rivera | 8 | 2026-2035 | |
| 58 | Arturo Rodríguez# | 8 | 2027-2036 | |
| 58 | Pedro Santos | 8 | 2022-2034 | |
| 58 | Shiki Sanu# | 8 | 2030-2037 | |
| 58 | Ray Sears* | 8 | 2015-2026 | |
| 58 | Thom Wilcox* | 8 | 2015-2028 | |
| 76 | Armando Alvarado | 7 | 2022-2036 | |
| 76 | Anselmo Berneu# | 7 | 2031-2037 | |
| 76 | Daniel Clark | 7 | 2014-2018 | |
| 76 | Sébastien Cornu# | 7 | 2035-2037 | |
| 76 | Barry Dempsey | 7 | 2021-2028 | |
| 76 | Ye Der | 7 | 2015-2029 | |
| 76 | Juan González | 7 | 2022-2025 | |
| 76 | Richard Jost# | 7 | 2029-2036 | |
| 76 | Gilberto Juárez# | 7 | 2028-2037 | |
| 76 | Carlos Kramer | 7 | 2021-2026 | |
| 76 | Pablo León | 7 | 2014-2024 | |
| 76 | John MacGregor | 7 | 2016-2029 | |
| 76 | José Marín | 7 | 2020-2032 | |
| 76 | Enrique Marroquín | 7 | 2020-2032 | |
| 76 | António Martínez# | 7 | 2024-2035 | |
| 76 | Gustavo Mateo | 7 | 2020-2034 | |
| 76 | Paco Muńóz# | 7 | 2030-2035 | |
| 76 | Teruo Nakayama | 7 | 2023-2026 | |
| 76 | Sergio Ortíz# | 7 | 2025-2037 | |
| 76 | Iván Pérez | 7 | 2017-2025 | |
| 76 | Alfredo Pizarro# | 7 | 2026-2037 | |
| 76 | Doug Reed | 7 | 2016-2023 | |
| 76 | Randy Rehling | 7 | 2023-2032 | |
| 76 | Raúl Robles | 7 | 2018-2025 | |
| 76 | Clay Rush | 7 | 2016-2032 |
