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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Kade Eagleton | 2032-2032 | .253 | 5 | 52 | 0 | 0 | 0 | 0.00 | 0 |
| Enrique Echevarría | 2021-2021 | .148 | 1 | 6 | 0 | 0 | 0 | 0.00 | 0 |
| Craig Edmunds | 2020-2020 | .444 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Landon Edwards | 2033-2033 | .171 | 0 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| George Eisenhauer | 2033-2033 | .000 | 0 | 0 | 2 | 0 | 0 | 2.08 | 17 |
| Jim Eisenmenger | 2031-2032 | .000 | 0 | 0 | 0 | 2 | 0 | 5.84 | 33 |
| Nassim El-Badwi | 2031-2033 | .000 | 0 | 0 | 17 | 11 | 0 | 3.38 | 151 |
| Alan Elder | 2017-2031 | .320 | 33 | 134 | 0 | 0 | 0 | 0.00 | 0 |
| Terrence Eler | 2017-2030 | .297 | 83 | 229 | 0 | 0 | 0 | 0.00 | 0 |
| Wallace Elgie | 2016-2022 | .000 | 0 | 0 | 4 | 7 | 3 | 8.29 | 76 |
| Bernardo Elías | 2021-2031 | .310 | 17 | 94 | 0 | 0 | 0 | 0.00 | 0 |
| Miguel Elías | 2033-2033 | .390 | 0 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| Jim Eliott | 2022-2022 | .000 | 0 | 0 | 0 | 2 | 0 | 3.66 | 17 |
| Ramón Elizondo | 2017-2024 | .000 | 0 | 0 | 14 | 17 | 54 | 4.28 | 116 |
| Harold Elkins | 2024-2031 | .000 | 0 | 0 | 7 | 7 | 2 | 4.56 | 65 |
| Earl Ellis | 2021-2021 | .318 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Joe Ellis | 2023-2024 | .000 | 0 | 0 | 5 | 5 | 3 | 5.04 | 69 |
| Arnout Els | 2027-2029 | .000 | 0 | 0 | 7 | 9 | 2 | 4.70 | 103 |
| Augusto Encarnación | 2027-2027 | .250 | 3 | 16 | 0 | 0 | 0 | 0.00 | 0 |
| Alberto Enríquez | 2023-2033 | .278 | 14 | 77 | 0 | 0 | 0 | 0.00 | 0 |
| Anastasio Enríquez | 2021-2022 | .000 | 0 | 0 | 1 | 1 | 0 | 3.27 | 26 |
| Dermot Eridge | 2033-2033 | .000 | 0 | 0 | 1 | 2 | 7 | 4.22 | 8 |
| António Escalante | 2033-2033 | .186 | 1 | 6 | 0 | 0 | 0 | 0.00 | 0 |
| Vicente Escamilla | 2031-2033 | .000 | 0 | 0 | 1 | 3 | 3 | 3.58 | 37 |
| Álex Escobar | 2022-2022 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Gabriel Escobar | 2032-2033 | .000 | 0 | 0 | 4 | 3 | 12 | 3.81 | 67 |
| Germán Espantoso | 2032-2032 | .347 | 0 | 16 | 0 | 0 | 0 | 0.00 | 0 |
| Armando Esparza | 2015-2025 | .291 | 27 | 97 | 0 | 0 | 0 | 0.00 | 0 |
| Salvador Esparza | 2030-2032 | .297 | 4 | 18 | 0 | 0 | 0 | 0.00 | 0 |
| Clark Espinosa | 2021-2029 | .219 | 2 | 18 | 0 | 0 | 0 | 0.00 | 0 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Pedro Espinoza | 2022-2030 | .000 | 0 | 0 | 5 | 5 | 0 | 4.64 | 76 |
| Álex Estrada | 2024-2030 | .276 | 31 | 157 | 0 | 0 | 0 | 0.00 | 0 |
| Javier Estrada | 2019-2019 | .000 | 0 | 0 | 3 | 4 | 0 | 5.49 | 67 |
| León Estrada | 2022-2029 | .222 | 3 | 60 | 0 | 0 | 0 | 0.00 | 0 |
| Sixto Estrada | 2033-2033 | .215 | 2 | 13 | 0 | 0 | 0 | 0.00 | 0 |
| Chris Etheridge | 2031-2031 | .312 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Craig Evans | 2023-2026 | .000 | 0 | 0 | 11 | 10 | 1 | 5.17 | 123 |
| Mark Evans | 2026-2026 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Sean Evans | 2021-2021 | .000 | 0 | 0 | 1 | 0 | 4 | 2.16 | 4 |
| Dale Everest | 2031-2032 | .225 | 5 | 34 | 0 | 0 | 0 | 0.00 | 0 |
| Vern Ewing | 2024-2025 | .217 | 1 | 20 | 0 | 0 | 0 | 0.00 | 0 |
