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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Alejandro Ramos# | 2.42 | 2021-2025 | |
| 2 | Enrique Madrid | 2.45 | 2021-2023 | |
| 3 | Gonzalo Montés | 2.47 | 2022-2026 | |
| 3 | António Marés# | 2.47 | 2021-2022 | |
| 5 | Bob Browning# | 2.58 | 2023-2025 | |
| 6 | Ismael Lara# | 2.70 | 2024-2027 | |
| 7 | Armando Ortíz# | 2.71 | 2021-2025 | |
| 8 | Loren Berdine# | 2.77 | 2027-2029 | |
| 9 | Rusty Swanson# | 2.80 | 2023-2025 | |
| 10 | José Santiago# | 2.83 | 2024-2027 | |
| 11 | Gabriel Escobar# | 2.97 | 2022-2025 | |
| 12 | Alberto Solís# | 2.99 | 2025-2027 | |
| 13 | José López# | 3.00 | 2026-2028 | |
| 14 | Morihiro Sai# | 3.06 | 2025-2027 | |
| 15 | Hänsel Freeh | 3.09 | 2020-2021 | |
| 16 | Cisco Pérez# | 3.17 | 2029-2030 | |
| 17 | Edward Scarborough# | 3.23 | 2026-2029 | |
| 18 | Nick Richie# | 3.26 | 2022-2024 | |
| 18 | Sjoerd Reynoud# | 3.26 | 2027-2029 | |
| 20 | Josef Strolz# | 3.32 | 2023-2025 | |
| 21 | António Muńóz# | 3.37 | 2026-2027 | |
| 22 | Pedro Adame# | 3.50 | 2026-2028 | |
| 23 | Marnix van Rijn# | 3.84 | 2026-2029 | |
| 24 | Zach Pinyerrel# | 3.93 | 2029-2031 | |
| 25 | Felipe Pereira# | 4.12 | 2024-2027 | |
| 26 | Kent Horton# | 4.52 | 2030-2031 | |
| 27 | Ryan Dull# | 4.89 | 2024-2028 |
