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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Mo Eayrs | 2029-2029 | .171 | 1 | 15 | 0 | 0 | 0 | 0.00 | 0 |
| Armaan Ebrahim | 2027-2028 | .246 | 6 | 43 | 0 | 0 | 0 | 0.00 | 0 |
| Bill Edmonds | 2025-2026 | .000 | 0 | 0 | 4 | 3 | 4 | 1.38 | 56 |
| Gene Edwards | 2020-2021 | .000 | 0 | 0 | 5 | 1 | 0 | 2.49 | 60 |
| Landon Edwards | 2028-2028 | .185 | 1 | 26 | 0 | 0 | 0 | 0.00 | 0 |
| Patrick Eggen | 2027-2028 | .193 | 1 | 19 | 0 | 0 | 0 | 0.00 | 0 |
| David Elías | 2028-2028 | .247 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Miguel Elías | 2027-2029 | .215 | 16 | 97 | 0 | 0 | 0 | 0.00 | 0 |
| Antenor Elizalde | 2024-2024 | .000 | 0 | 0 | 1 | 2 | 1 | 2.22 | 23 |
| Ramiro Elizondo | 2026-2026 | .000 | 0 | 0 | 3 | 1 | 6 | 2.63 | 51 |
| Harold Elkins | 2020-2022 | .000 | 0 | 0 | 14 | 7 | 0 | 2.53 | 163 |
| Félix Ellard | 2029-2029 | .208 | 1 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Pete Elliott | 2020-2020 | .000 | 0 | 0 | 0 | 1 | 0 | 27.00 | 1 |
| John Ellwanger | 2029-2029 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Arnout Els | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 1 | 6.75 | 12 |
| Beau Emery | 2026-2026 | .207 | 0 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Augusto Encarnación | 2023-2024 | .248 | 3 | 13 | 0 | 0 | 0 | 0.00 | 0 |
| Raúl Encarnación | 2020-2020 | .000 | 0 | 0 | 2 | 2 | 0 | 4.95 | 32 |
| John Ennis | 2024-2024 | .195 | 2 | 26 | 0 | 0 | 0 | 0.00 | 0 |
| Alberto Enríquez | 2021-2021 | .281 | 0 | 14 | 0 | 0 | 0 | 0.00 | 0 |
| Anastasio Enríquez | 2027-2027 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 1 |
| Archie Erickson | 2028-2029 | .000 | 0 | 0 | 8 | 1 | 13 | 1.28 | 100 |
| Bill Erickson | 2025-2027 | .192 | 5 | 77 | 0 | 0 | 0 | 0.00 | 0 |
| Ijsbrand Erkelens | 2029-2029 | .239 | 1 | 24 | 0 | 0 | 0 | 0.00 | 0 |
| Lou Erwin | 2024-2026 | .000 | 0 | 0 | 3 | 6 | 3 | 3.06 | 68 |
| Vicente Escamilla | 2023-2024 | .000 | 0 | 0 | 2 | 2 | 3 | 2.66 | 31 |
| Andrés Escobar | 2024-2024 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Augusto Escobar | 2029-2029 | .318 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Gabriel Escobar | 2029-2029 | .000 | 0 | 0 | 0 | 1 | 0 | 13.50 | 3 |
| Gabriel Escobar | 2022-2025 | .000 | 0 | 0 | 25 | 18 | 0 | 2.97 | 356 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| António Escobeda | 2029-2029 | .242 | 1 | 17 | 0 | 0 | 0 | 0.00 | 0 |
| Germán Espantoso | 2028-2028 | .500 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Héctor Espiga | 2029-2029 | .226 | 1 | 22 | 0 | 0 | 0 | 0.00 | 0 |
| Alberto Esquivel | 2026-2026 | .195 | 0 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Álex Estrada | 2021-2022 | .228 | 4 | 14 | 0 | 0 | 0 | 0.00 | 0 |
| José Estrada | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Chris Etheridge | 2024-2024 | .391 | 0 | 4 | 0 | 0 | 0 | 0.00 | 0 |
| Carlos Evangelho | 2026-2028 | .294 | 7 | 77 | 0 | 0 | 0 | 0.00 | 0 |
| Dale Everest | 2026-2027 | .215 | 3 | 16 | 0 | 0 | 0 | 0.00 | 0 |
