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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Francisco Burgos# | 0.853 | 2028 | |
| 2 | Armando Ortíz# | 1.177 | 2025 | |
| 3 | Paul Addison# | 1.186 | 2026 | |
| 4 | Tomás Vargas# | 1.280 | 2026 | |
| 5 | Benjamin Busto# | 1.319 | 2027 | |
| 6 | Ismael Soto | 1.355 | 2021 | |
| 7 | Tony Solíz# | 1.376 | 2024 | |
| 8 | Bob Browning# | 1.450 | 2025 | |
| 9 | Baruc Garibay# | 1.627 | 2027 | |
| 10 | Iván Vázquez# | 1.662 | 2027 | |
| 11 | Felipe Lozano# | 1.748 | 2028 | |
| 12 | Don Bender | 1.831 | 2020 | |
| 13 | Jorge Travieso# | 1.832 | 2028 | |
| 14 | Alberto Solís# | 1.885 | 2027 | |
| 15 | Júlio Vázquez# | 1.912 | 2026 | |
| 16 | Enrique Castro# | 1.933 | 2027 | |
| 17 | Santiago Alonza# | 1.958 | 2023 | |
| 18 | Tony Moreno# | 1.978 | 2028 | |
| 19 | Luis Hernández# | 2.017 | 2025 | |
| 20 | Maru Pao Pao# | 2.030 | 2027 | |
| 20 | Juan López# | 2.030 | 2021 | |
| 20 | Francisco Burgos# | 2.030 | 2027 | |
| 23 | Tyler Lund# | 2.048 | 2026 | |
| 24 | Ron Madison# | 2.053 | 2020 | |
| 25 | Rusty Swanson# | 2.056 | 2025 | |
| 26 | Ramón Castaneda | 2.057 | 2025 | |
| 27 | Darius Baxa# | 2.098 | 2026 | |
| 28 | Gabriel Escobar# | 2.101 | 2025 | |
| 29 | Osiris St. Brown# | 2.103 | 2028 | |
| 30 | Brad Cunnick# | 2.114 | 2020 | |
| 31 | Jeff Lee# | 2.122 | 2020 | |
| 31 | Rust Cohle# | 2.122 | 2025 | |
| 33 | Alberto Mendoza# | 2.127 | 2025 | |
| 34 | Marco Sledge# | 2.139 | 2028 | |
| 35 | Edward Scarborough# | 2.150 | 2027 | |
| 36 | Nicholas Beyer# | 2.167 | 2022 | |
| 37 | Pedro Álvarez# | 2.176 | 2020 | |
| 38 | Song-saeng Kim# | 2.195 | 2022 | |
| 39 | Alejandro Ramos# | 2.201 | 2023 | |
| 40 | Santos Guzowski# | 2.227 | 2025 | |
| 41 | Manuel Ceja# | 2.245 | 2027 | |
| 42 | Quinton Richards# | 2.250 | 2027 | |
| 43 | António Muñóz# | 2.254 | 2027 | |
| 44 | Ernest Torres# | 2.256 | 2020 | |
| 45 | Abdel Alamini# | 2.263 | 2026 | |
| 46 | Nick Richie# | 2.268 | 2023 | |
| 47 | Prince Nakamura# | 2.271 | 2023 | |
| 48 | Raymond Beauregard# | 2.285 | 2028 | |
| 49 | Won-min Yi# | 2.288 | 2027 | |
| 50 | Pedro Ramírez# | 2.292 | 2021 | |
| 51 | Victor de Meij# | 2.294 | 2024 | |
| 52 | Mark Bell# | 2.305 | 2021 | |
| 53 | Roger Murdock# | 2.308 | 2027 | |
| 54 | Vicente Romero# | 2.344 | 2028 | |
| 55 | Adrian Neumann# | 2.345 | 2021 | |
| 56 | Walt Cooley# | 2.363 | 2024 | |
| 57 | Ramiro García# | 2.367 | 2022 | |
| 58 | Alejandro Ramos# | 2.385 | 2024 | |
| 59 | Jason Troughton# | 2.411 | 2021 | |
| 60 | Steve Tedder# | 2.415 | 2028 | |
| 60 | Héctor Cortéz# | 2.415 | 2022 | |
| 62 | António Marés# | 2.429 | 2021 | |
| 63 | Ricardo Roquette | 2.433 | 2022 | |
| 63 | Gabriel Hernández# | 2.433 | 2021 | |
| 65 | Chet Saks# | 2.449 | 2028 | |
| 66 | Mack MacDonald# | 2.474 | 2025 | |
| 67 | Enrique Madrid | 2.492 | 2021 | |
| 68 | José Quiñones# | 2.504 | 2027 | |
| 69 | Orlando De Jesús# | 2.510 | 2021 | |
| 70 | António Marés# | 2.521 | 2022 | |
| 70 | Enrique García# | 2.521 | 2020 | |
| 72 | Jorge Reyna# | 2.541 | 2028 | |
| 73 | Arnold Safi# | 2.545 | 2027 | |
| 74 | Taro Ohayashi# | 2.550 | 2020 | |
| 75 | Rob Silva# | 2.559 | 2025 | |
| 76 | Ánibal Rivera# | 2.563 | 2022 | |
| 77 | Brewster Warble# | 2.566 | 2027 | |
| 78 | Sam Groves# | 2.569 | 2024 | |
| 79 | Ismael Lara# | 2.571 | 2026 | |
| 80 | Javier Pérez# | 2.579 | 2025 | |
| 81 | Shunen Takahashi# | 2.583 | 2021 | |
| 82 | Bob Payne# | 2.589 | 2022 | |
| 83 | Ramiro García# | 2.601 | 2024 | |
| 84 | Nicholas Adams# | 2.611 | 2023 | |
| 85 | José López# | 2.622 | 2026 | |
| 86 | Jon Shirley# | 2.634 | 2024 | |
| 87 | Pedro Adame# | 2.640 | 2028 | |
| 88 | Raúl Gómez# | 2.661 | 2024 | |
| 89 | Loren Berdine# | 2.672 | 2027 | |
| 90 | Loeck Visser# | 2.683 | 2025 | |
| 91 | Miguel Jiménez# | 2.685 | 2028 | |
| 92 | Glen Holland# | 2.687 | 2021 | |
| 93 | Morihiro Sai# | 2.700 | 2025 | |
| 93 | Harold Elkins# | 2.700 | 2021 | |
| 93 | Addick Lubbers# | 2.700 | 2023 | |
| 93 | Ciríaco Muro# | 2.700 | 2024 | |
| 93 | Chae-seong Kim# | 2.700 | 2021 | |
| 93 | Manuel Franco# | 2.700 | 2020 | |
| 99 | José Ruíz# | 2.713 | 2027 | |
| 99 | Héctor Rosado | 2.713 | 2021 |
