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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bill Edmonds | 0-2025 | 4 | 3 | .571 | 1.38 | 42 | 0 | 0 | 0 | 4 | 52.0 | 37 | 8 | 1 | 22 | 56 |
| Gene Edwards | 1-2023 | 5 | 1 | .833 | 2.49 | 26 | 2 | 0 | 0 | 0 | 65.0 | 54 | 18 | 1 | 18 | 60 |
| Antenor Elizalde | 0-2024 | 1 | 2 | .333 | 2.22 | 5 | 4 | 0 | 0 | 1 | 24.1 | 21 | 6 | 0 | 8 | 23 |
| Ramiro Elizondo | 0-2027 | 3 | 1 | .750 | 2.63 | 24 | 0 | 0 | 0 | 6 | 37.2 | 24 | 11 | 1 | 15 | 51 |
| Harold Elkins | 2-2023 | 14 | 7 | .667 | 2.53 | 24 | 24 | 7 | 2 | 0 | 192.0 | 184 | 54 | 6 | 47 | 163 |
| Pete Elliott | 0-2020 | 0 | 1 | .000 | 27.00 | 1 | 0 | 0 | 0 | 0 | 0.1 | 1 | 1 | 0 | 1 | 1 |
| Arnout Els | 0-2022 | 0 | 0 | .000 | 6.75 | 8 | 0 | 0 | 0 | 1 | 10.2 | 11 | 8 | 1 | 2 | 12 |
| Raúl Encarnación | 0-2020 | 2 | 2 | .500 | 4.95 | 16 | 2 | 0 | 0 | 0 | 40.0 | 44 | 22 | 3 | 21 | 32 |
| Anastasio Enríquez | 0-2018 | 0 | 0 | .000 | 0.00 | 1 | 0 | 0 | 0 | 0 | 1.0 | 2 | 0 | 0 | 1 | 1 |
| Lou Erwin | -1-2027 | 3 | 6 | .333 | 3.06 | 58 | 0 | 0 | 0 | 3 | 111.2 | 104 | 38 | 7 | 28 | 68 |
| Vicente Escamilla | 0-2027 | 2 | 2 | .500 | 2.66 | 25 | 0 | 0 | 0 | 3 | 44.0 | 41 | 13 | 0 | 18 | 31 |
| Gabriel Escobar | 2-2027 | 25 | 18 | .581 | 2.97 | 75 | 54 | 0 | 0 | 0 | 348.2 | 308 | 115 | 13 | 136 | 356 |
