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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ju-hyung O | 0-2020 | 0 | 2 | .000 | 6.14 | 5 | 0 | 0 | 0 | 0 | 7.1 | 11 | 5 | 0 | 4 | 9 |
| Carl O'Malloy | 0-2024 | 8 | 6 | .571 | 2.06 | 82 | 0 | 0 | 0 | 7 | 78.2 | 55 | 18 | 5 | 34 | 71 |
| Anderson O'Mara | 0-2025 | 2 | 2 | .500 | 2.22 | 10 | 10 | 0 | 0 | 0 | 44.2 | 44 | 11 | 0 | 9 | 18 |
| Aaron O'Neill | 0-2019 | 2 | 2 | .500 | 2.98 | 36 | 4 | 0 | 0 | 16 | 57.1 | 59 | 19 | 5 | 18 | 16 |
| Ed O'Quinn | 0-2026 | 13 | 3 | .812 | 2.84 | 25 | 25 | 1 | 1 | 0 | 155.1 | 140 | 49 | 12 | 53 | 121 |
| Ron O'Slattery | 0-2015 | 1 | 0 | 1.000 | 1.08 | 2 | 1 | 0 | 0 | 0 | 8.1 | 11 | 1 | 0 | 5 | 6 |
| Chris O'Toole | 0-2023 | 0 | 0 | .000 | 1.50 | 15 | 0 | 0 | 0 | 0 | 6.0 | 6 | 1 | 0 | 2 | 3 |
| Alin Oanta | 1-2018 | 11 | 9 | .550 | 5.51 | 28 | 24 | 0 | 0 | 0 | 125.2 | 153 | 77 | 8 | 62 | 87 |
| Héctor Ocampo | 2-2026 | 10 | 21 | .323 | 5.15 | 65 | 39 | 3 | 0 | 1 | 299.0 | 333 | 171 | 18 | 180 | 193 |
| Luis Ochoa | 0-3 | 2 | 0 | 1.000 | 5.28 | 15 | 0 | 0 | 0 | 2 | 15.1 | 15 | 9 | 0 | 8 | 11 |
| Jesús Olvero | 1-2020 | 11 | 6 | .647 | 4.22 | 150 | 0 | 0 | 0 | 11 | 151.1 | 137 | 71 | 18 | 84 | 186 |
| Carlos Ortega | 0-4 | 2 | 2 | .500 | 5.40 | 9 | 9 | 0 | 0 | 0 | 51.2 | 58 | 31 | 7 | 31 | 42 |
| Cisco Ortega | 0-2023 | 1 | 2 | .333 | 7.84 | 8 | 0 | 0 | 0 | 1 | 10.1 | 16 | 9 | 1 | 6 | 6 |
| José Ortíz | -1-2018 | 7 | 11 | .389 | 5.81 | 88 | 0 | 0 | 0 | 6 | 79.0 | 104 | 51 | 11 | 54 | 83 |
| Luis Ortíz | 3-2020 | 15 | 16 | .484 | 3.60 | 138 | 43 | 4 | 0 | 9 | 372.1 | 379 | 149 | 34 | 138 | 301 |
| Vincente Ortíz | 0-2022 | 5 | 6 | .455 | 4.81 | 41 | 0 | 0 | 0 | 16 | 43.0 | 46 | 23 | 1 | 27 | 17 |
| John Orton | 0-2026 | 0 | 0 | .000 | 1.93 | 11 | 0 | 0 | 0 | 0 | 9.1 | 7 | 2 | 0 | 12 | 3 |
| Jesús Otero | 0-2026 | 2 | 1 | .667 | 1.95 | 12 | 0 | 0 | 0 | 3 | 27.2 | 24 | 6 | 0 | 13 | 24 |
| Bill Oulton | 0-2020 | 5 | 6 | .455 | 2.90 | 17 | 17 | 1 | 0 | 0 | 118.0 | 98 | 38 | 4 | 45 | 115 |
| Rich Overby | 0-2026 | 0 | 0 | .000 | 11.74 | 4 | 0 | 0 | 0 | 0 | 7.2 | 14 | 10 | 2 | 5 | 7 |
| Doruk Oyan | 0-2025 | 13 | 15 | .464 | 4.40 | 60 | 39 | 1 | 0 | 0 | 278.1 | 271 | 136 | 28 | 153 | 217 |
