| Saturday, December 29th, 2018 |
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| Placed MR Manuel Alfonso on the active roster. |
| Sunday, December 16th, 2018 |
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| Signed free agent MR Manuel Alfonso to a 1-year contract worth a total of $690,000. |
| Saturday, December 1st, 2018 |
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| Drafted SP Paul Moore in the 2018 Rule 5 Draft (Round 1, Pick 20, 20th overall Pick), from the Irvine Gang Green. | | Drafted SP Yasuyuki Ishii in the 2018 Rule 5 Draft (Round 2, Pick 20, 48th overall Pick), from the St. Louis Browns. | | Drafted MR Lorenzo Ramos in the 2018 Rule 5 Draft (Round 3, Pick 20, 76th overall Pick), from the Orlando Calrissian. | | Drafted SS Fernando De La Cruz in the 2018 Rule 5 Draft (Round 4, Pick 20, 104th overall Pick), from the Pocatello Boccabellas. | | Drafted 2B Ramón Martínez in the 2018 Rule 5 Draft (Round 5, Pick 20, 132nd overall Pick), from the Austin River Sharks. | | Drafted LF Santiago Farías in the 2018 Rule 5 Draft (Round 6, Pick 20, 160th overall Pick), from the Pocatello Boccabellas. | | Drafted SP Pepe Fernández in the 2018 Rule 5 Draft (Round 7, Pick 20, 188th overall Pick), from the Indianapolis Lions. | | Lost 3B Wilford Lush in the Rule 5 Draft to the St Charles Sheens. | | Drafted MR Ramiro Fernández in the 2018 Rule 5 Draft (Round 8, Pick 20, 216th overall Pick), from the Chicago Machine. |
| Friday, November 23rd, 2018 |
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| Traded 22-year-old reliever António Ojeda and 23-year-old minor league starting pitcher William Watson to the St. Louis Browns, getting 28-year-old minor league first baseman Jesús Ontiveros, 30-year-old third baseman Marc-André Dumont and 22-year-old minor league center fielder Yoshitoki Kouda in return. | | Traded 25-year-old shortstop Rafael González, 24-year-old center fielder Carlos García, 24-year-old reliever Edward Cadle and 23-year-old reliever Héctor Reyes to the Hendersonville Hitmen, getting 31-year-old second baseman Jeff Cole, 29-year-old reliever António López, 21-year-old minor league third baseman Wilford Lush, 25-year-old minor league starting pitcher Lyle Brown and 23-year-old minor league starting pitcher Harvey Bradridge in return. |
| Tuesday, November 20th, 2018 |
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| 2B Millard Henderson received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Dave Lewis becomes a free-agent. | | C Guillermo Ortíz received a 1-year contract through automatic renewal worth a total of $400,000. | | MR António Ojeda received a 1-year contract through automatic renewal worth a total of $400,000. | | 3B Tommy Hahn becomes a free-agent. | | LF Pablo Lucero received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Roberto Bojórquez becomes a free-agent. | | MR Juan Nieto received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Tyler Law becomes a free-agent. | | SP Eduardo Martínez received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Gordon Brown becomes a free-agent. | | SS Riley Cassidy becomes a free-agent. | | MR Fergus Wakeford received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Pancho García received a 1-year contract through automatic renewal worth a total of $400,000. |
| Saturday, November 17th, 2018 |
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| 2B Allen Dickerson was not offered arbitration, becomes a free agent. |
| Tuesday, November 13th, 2018 |
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| Signed SP Cipriano Montáñez to a 4-year contract extension worth a total of $69,600,000. |
| Saturday, October 27th, 2018 |
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| SP Cipriano Montáñez voids his last optional contract year. | | MR Raúl Camacho has executed his last optional contract year. |
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