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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Date | Player | Hits | |
|---|---|---|---|
| 05/30/2015 | Júlio Gruzmán | 6 Hits in 6 AB, 6 RBI versus Atlanta while playing for Lexington | |
| 08/11/2017 | Domingo García | 6 Hits in 7 AB, 3 RBI versus Louisville while playing for Phoenix | |
| 05/28/2018 | Bob Campbell | 6 Hits in 6 AB, 1 HR and 3 RBI versus Lexington while playing for Boston | |
| 05/09/2021 | Héctor Cortéz | 6 Hits in 6 AB, 2 RBI versus Phoenix while playing for Toledo |
